Neoplasms

All Conditions

Digestive System Diseases

Rare Diseases

Carcinoma

Carcinoma, Squamous Cell

Esophageal Neoplasms

Esophageal Squamous Cell Carcinoma

Gastrointestinal Neoplasms

Digestive System Neoplasms

Head and Neck Neoplasms

Gastrointestinal Diseases

Esophageal Diseases

Esophageal Cancer

Radiotherapy 54 Gy was administered in 1.8 Gy fractions 5 times weekly. S-1 70mg/m2 was administered on days 1-14 and 29-42

Radiotherapy 60 Gy was administered in 2Gy fractions 5 times weekly.

Radiotherapy was administered in 1.8 Gy fractions 5 times weekly to a total dose of 54 Gy.

Radiotherapy 54 Gy

Radiotherapy was administered in 2 Gy fractions 5 times weekly to a total dose of 60Gy.

Radiotherapy 60 Gy

S-1 70mg/m2 was administered on days 1-14 and 29-42.

MING CHEN, PHD

XIANGHUI DU, MD

youngling JI, MD

weiguo zhu, MD

This was a randomised, multicenter, phase 3 trial. Patients who were age of 70 years or older with histologically confirmed esophageal cancer were randomly assigned to S-1 concurrent with radiotherapy or radiotherapy alone.The primary endpoint was overall survival.

S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer

S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus: A Prospective, Randomized, Multi-center Phase-III Study

assessed with the European Organisation for Research and Treatment of Cancer quality-of-life core questionnaire QLQ-C30

assessed with the European Organisation for Research and Treatment of Cancer quality-of-life the oesophagus-specific questionnaire QLQ-OES18

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer	NCT02813967	Esophageal Canc... Chemoradiation	Radiotherapy 54... Radiotherapy 60... S-1	70 Years - 85 Years	Zhejiang Cancer Hospital
S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer	NCT02813967	Esophageal Canc... Chemoradiation	Radiotherapy 54... Radiotherapy 60... S-1	70 Years - 85 Years	Zhejiang Cancer Hospital

Spots Global Cancer Trial Database for radiotherapy 54 gy