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Fluorodeoxyglucose F18

At the inclusion, both all patients, a 18F-FDG-PET/CT and a dw-MRI will be performed

A FDG PET scan and a diffusion-weighted Magnetic Resonance Imaging will be performed to compare the efficacy to diagnose relapse in thyroid carcinoma

MRI imaging

Pierre Vera, MD, PhD

The purpose of the study is to evaluate the concordance between the 18F-PET/CT under thyrotropin stimulation and the diffusion-weighted Magnetic Resonance Imaging, in the detection of residual mass in 40 patients with partial response or relapsed differentiated thyroid carcinoma.

The schedule and the procedures of the study are the following ones :

* Baseline evaluation :

  * Clinical examination with neck echography after rhTSH stimulation
  * Normal whole body scan
* First visit (inclusion):

  18F-FDG PET/CT DW-MRI of the neck if possible performed shortly after the PET CT or within following days
* Following visits: at 6 months and 12 months

  * DW-MRI of the neck performed shortly after the PET CT or within following days.
  * Ultrasonography guided fine needle aspiration for cytology for detection of cervical metastases and identifying thyroglobuline in the needle washout fluid if needed and in case of positivity of either PET or DW-MRI exams.
  * Histological assessment of biopsies if performed

Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma

Preliminary Study of the Interest of Diffusion-weighted Magnetic Resonance Imaging in the Early Detection of Differentiated Thyroid Carcinoma Cervical Recurrence. Comparison with18F-FDG PET/CT

To assess concordance between FDG PET-CT scan and MRI in detection of cervical residual masses in 40 patients in Partial Response or in relapse cervical well-differentiated thyroid carcinoma

Centre Henri Becquerel

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma	NCT02515084	Thyroid Cancer Relapse	PET MRI imaging	18 Years -	Centre Henri Becquerel
Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma	NCT02515084	Thyroid Cancer Relapse	PET MRI imaging	18 Years -	Centre Henri Becquerel

Spots Global Cancer Trial Database for recurrence thyroid cancer