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Spots Global Cancer Trial Database for Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma

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Trial Identification

Brief Title: Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma

Official Title: Preliminary Study of the Interest of Diffusion-weighted Magnetic Resonance Imaging in the Early Detection of Differentiated Thyroid Carcinoma Cervical Recurrence. Comparison with18F-FDG PET/CT

Study ID: NCT02515084

Interventions

PET
MRI imaging

Study Description

Brief Summary: The purpose of the study is to evaluate the concordance between the 18F-PET/CT under thyrotropin stimulation and the diffusion-weighted Magnetic Resonance Imaging, in the detection of residual mass in 40 patients with partial response or relapsed differentiated thyroid carcinoma.

Detailed Description: The schedule and the procedures of the study are the following ones : * Baseline evaluation : * Clinical examination with neck echography after rhTSH stimulation * Normal whole body scan * First visit (inclusion): 18F-FDG PET/CT DW-MRI of the neck if possible performed shortly after the PET CT or within following days * Following visits: at 6 months and 12 months * DW-MRI of the neck performed shortly after the PET CT or within following days. * Ultrasonography guided fine needle aspiration for cytology for detection of cervical metastases and identifying thyroglobuline in the needle washout fluid if needed and in case of positivity of either PET or DW-MRI exams. * Histological assessment of biopsies if performed

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Centre Henri Becquerel, Rouen, , France

Contact Details

Name: Pierre Vera, MD, PhD

Affiliation: Centre Henri Becquerel

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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