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Epstein-Barr virus associated hemophagocytic lymphohistiocytosis patients with imaging confirmed intestinal involvement

Segmental bowel resection combined with liposomal doxorubicin, etoposide, and methylprednisolone administered in 2 week cycles for 2 cycles

Segmental bowel resection combined with the DEP regimen

Zhao Wang, MD

EBV-HLH is a rare disease with high mortality, especially for those with intestinal involvement. In order to reduce disease burden and improve survival of these patients, we conduct a prospective observational study to explore the efficacy and safety of segmental resection combined with the DEP regimen.

Epstein-Barr virus associated hemophagocytic lymphohistiocytosis is a rare disease with high mortality, especially for those with intestinal involvement. Some of them still died despite early control of the disease due to severe complications, such as gastrointestinal bleeding. In order to reduce disease burden and improve survival of these patients, we conduct a prospective observational study to explore the efficacy and safety of segmental resection combined with the DEP regimen.

Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement

Efficacy and Safety of Segmental Resection Combined With the DEP Regimen for Epstein-Barr Virus Associated Hemophagocytic Lymphohistiocytosis With Intestinal Involvement

The percentage of cases that achieved complete response (CR) and partial response (PR) after treatment.

Beijing Friendship Hospital

Professor and Head of hematology

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement	NCT06131489	Hemophagocytic ... Epstein-Barr Vi... Bowel Resection	Segmental bowel...	18 Years -	Beijing Friendship Hospital
Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement	NCT06131489	Hemophagocytic ... Epstein-Barr Vi... Bowel Resection	Segmental bowel...	18 Years -	Beijing Friendship Hospital

Spots Global Cancer Trial Database for segmental bowel resection combined with the dep regimen