* Participants assigned to usual care will receive a packet of instructions with information about how to complete weekly surveys via a link that will be emailed to them
* Participants in both arms will be asked to complete a total of five surveys: baseline, at the end of each of three weeks, and a final survey one month later

* Participants will listen to mindfulness meditations daily over the course of three weeks.
* Participants in both arms will be asked to complete a total of five surveys: baseline, at the end of each of three weeks, and a final survey one month later

Participants assigned to either condition who do not have a personal electronic device for listening to meditations or completing survey will receive a loaned device from the study team.

Mindfulness meditation

Usual care packet

Brian Carpenter, Ph.D.

The current study examines the effects of a 3-week, at-home mindfulness mediation intervention (MMI) to address psychological and physical distress in patients with gynecologic cancer.

A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients

-On the 14-item Hospital Anxiety and Depression Scale (HADS) symptoms of anxiety (7) and depression (7) are rated on a scale from 0 (less severe) to 3 (more severe).

-Patients rate distress on a scale from 0 (no distress) to 10 (extreme distress).

-includes 9 items to measure the severity of fatigue-related symptoms on a scale from 0 (no fatigue) to 10 (fatigue as bad as you can imagine). Items include ratings of fatigue at three time points: fatigue when it is at its "worst," fatigue when it is at its "usual" level, and fatigue as it is experienced "now," in the moment.

-The Edmonton Symptoms Assessment Scale Revised is a 10-item scale that measures severity of 10 physical and psychological symptoms (e.g., nausea, drowsiness, tiredness, anxiety) on a scale from 0 (e.g., no nausea) to 10 (e.g., worst possible nausea).

-measures two emotion regulation strategies, cognitive reappraisal and expressive suppression. Respondents rate 10 items about these strategies on a scale from 1 (strongly disagree) to 7 (strongly agree).

-Will assess 20 items from four subscales (acceptance, rumination, positive reappraisal, putting into perspective, and self-blame)

-Assesses observing, describing, acting with awareness, non-judging, and non-reactivity. Participants rate 15 items on a scale from 1 (never or very rarely true) to 5 (very often or always true).

-20-item scale that measures overall compassion for the self. The items are divided into five subscales that correspond to the five components of self-compassion. Items are rated from 1 (not at all true) to 5 (always true).

-10-item measure of globally perceived stress. The measure invites participants to retrospectively report their feelings and thoughts about various topics during the last month, including "how often \[you\] have felt upset because of something that happened unexpectedly," "how often \[you\] have felt that things were going your way," and "how often \[you\] could not cope with all the things that you had to do." Participants rate each item on a scale of 0 (Never) to 5 (Very Often), and a higher score indicates greater stress.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients	NCT04072406	Stage III Gynec... Stage IV Gyneco...	Mindfulness med... Usual care pack...	18 Years -	Washington University School of Medicine
A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients	NCT04072406	Stage III Gynec... Stage IV Gyneco...	Mindfulness med... Usual care pack...	18 Years -	Washington University School of Medicine

Spots Global Cancer Trial Database for stage iv gynecologic cancer