Neoplasms

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Carcinoma

Carcinoma, Squamous Cell

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Neoplasms, Squamous Cell

IMRT on the primitive site and the lymph nodes. +/- Concomitant chemotherapy at the discretion of the meeting multidisciplinary

transoral resection of the primary tumor, with cervical lymph node dissection. Radiotherapy complementary according to the histological criteria of severity

The technique of transoral surgery will be left to the choice of the surgeon according to the equipment and the experience of the team and will be gathered. The options are: transoral surgery robot-assisted, endoscopic laser transoral surgery, transoral laser surgery classical instruments. The exact description of the resected area will be collected. of the cross-sections will be made for extemporaneous analysis if necessary in lateral margins and deep until complete excision.

transoral resection

Intensity modulation radiotherapy (RCMI or IMRT) will be performed using techniques static or rotational (arctherapy, tomotherapy). Restraint is recommended with thermoformed mask

IMRT

Philippe Gorphe, MD

Thibaud Motreff

Compare patients' feelings in terms of swallowing ability assessed by the overall score of MD Anderson Dysphagia Inventory (MDADI) 2 years after starting treatment between patients who have been treated with IMRT and those who were treated by transoral surgery for a squamous cell carcinoma of the early stage oropharynx.

IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas

Prospective Non-randomized Comparative Study Between IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas of Early Local Stage of Oropharynx

Score goes from 20 to 100. A higher score means a better ability to swallow

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas	NCT04224389	Squamous Cell C...	transoral resec... IMRT	18 Years -	Gustave Roussy, Cancer Campus, Grand Paris
IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas	NCT04224389	Squamous Cell C...	transoral resec... IMRT	18 Years -	Gustave Roussy, Cancer Campus, Grand Paris
IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas	NCT04224389	Squamous Cell C...	transoral resec... IMRT	18 Years -	Gustave Roussy, Cancer Campus, Grand Paris

Spots Global Cancer Trial Database for transoral resection