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Spots Global Cancer Trial Database for Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses

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Trial Identification

Brief Title: Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses

Official Title: Open-Label Study to Assess Safety and Efficacy of Imiquimod 5% Cream Applied 3 Days Per Week in 1 or 2 Cycles for Treatment of Actinic Keratoses on the Head

Study ID: NCT00175643

Interventions

imiquimod

Study Description

Brief Summary: It is believed that imiquimod 5% cream has the potential to be an effective treatment for actinic keratoses. The purpose of this study is to evaluate the duration of the effect of topical imiquimod 5% topical cream for the treatment of actinic keratoses.

Detailed Description: This study will assess the safety and efficacy of imiquimod 5% cream applied to actinic keratoses on the head to reduce the size of lesions. The objective is to analyze the effect of dose cycling with respect to the complete clearance rate when imiquimod 5% cream is applied 3 times per week for 4 weeks in 1 or 2 cycles. The complete clearance rate is defined as the proportion of subjects with no clinically visible AK lesions in the treatment area at the end of cycle 1 or the end of cycle 2.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Clinical Trials Unit, Skin Care Centre, UBC Dermatology, Vancouver, British Columbia, Canada

Contact Details

Name: Jason K Rivers, M.D.

Affiliation: Division of Dermatology, University of British Columbia

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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