Spots Global Cancer Trial Database for Study of Temozolomide to Treat Newly Diagnosed Brain Metastases
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Trial Identification
Brief Title: Study of Temozolomide to Treat Newly Diagnosed Brain Metastases
Official Title: A Phase II Study of Temozolomide (TMZ) Following Stereotactic Radiosurgery (SRS) for Patients With Newly Diagnosed Brain Metastases
Study ID: NCT00717275
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to determine if administering temozolomide after completion of stereotactic radiosurgery helps control existing brain metastases and prevents the developement of new brain metastases.
Detailed Description: Brain metastases represent a heterogenous group of system tumors whose presence in the central nervous system result in profound neurological devastation. Existing therapies for brain metastases are focused on improving both neurologic function and survival. Therapies aimed at controlling the tumor both at the site of the brain metastases and the rest of the brain have the potential to improve outcomes and quality of life. The combined use of stereotactic radiosurgery followed by temozolomide may represent such a strategy.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Florida, Gainesville, Florida, United States
Contact Details
Name: Erin M Dunbar, MD
Affiliation: University of Florida
Role: PRINCIPAL_INVESTIGATOR
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