Spots Global Cancer Trial Database for stereotactic radiosurgery
Every month we try and update this database with for stereotactic radiosurgery cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
Stereotactic Radiation Therapy in Treating Patients With Prostate Cancer | NCT00619515 | Prostate Cancer | questionnaire a... implanted fiduc... stereotactic ra... | - 120 Years | Case Comprehensive Cancer Center | |
Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria) | NCT05178472 | Hematopoietic a... Malignant Solid... Metastatic Mali... | Immunotherapy Stereotactic Ra... Vertebroplasty | 18 Years - | Ohio State University Comprehensive Cancer Center | |
Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma | NCT00185861 | Brain Cancer | Arsenic Trioxid... Stereotactic ra... | 18 Years - | Stanford University | |
Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors | NCT00547131 | Brain and Centr... Metastatic Canc... | temozolomide laboratory biom... liquid chromato... mass spectromet... pharmacological... conventional su... stereotactic ra... | 18 Years - 120 Years | City of Hope Medical Center | |
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases | NCT00002708 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Radiation Therapy Oncology Group | |
Hypofractionated Image Guided Radiation Therapy in Treating Patients With Stage IV Breast Cancer | NCT01706432 | Central Nervous... Invasive Ductal... Invasive Ductal... Invasive Lobula... Invasive Lobula... Liver Metastase... Lobular Breast ... Lung Metastases Male Breast Can... Medullary Ducta... Mucinous Ductal... Papillary Ducta... Recurrent Breas... Stage IV Breast... Tubular Ductal ... Tumors Metastat... | hyperfractionat... laboratory biom... stereotactic ra... | 18 Years - | University of Chicago | |
Stereotactic Radiosurgery Prognosis Assessment for Spinal Tumors Based on Radiomics | NCT05369689 | Stereotactic Ra... Spinal Tumor Radiomics Prognosis | No intervention... | 18 Years - 80 Years | Peking University Third Hospital | |
Stereotactic Radiation in Vestibular Schwannoma | NCT01449604 | Vestibular Schw... | stereotactic ra... stereotactic ra... | 18 Years - 80 Years | Ramathibodi Hospital | |
Stereotactic Radiosurgery in Treating Patients With Brain Metastases | NCT00811655 | Metastatic Canc... Unspecified Adu... | therapeutic con... stereotactic ra... | 18 Years - | Duke University | |
A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases | NCT03497767 | Metastatic Non ... | Osimertinib Stereotactic Ra... | 18 Years - | Trans Tasman Radiation Oncology Group | |
Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-100M for the Treatment of Melanoma Brain Metastases | NCT05341349 | Clinical Stage ... Melanoma of Unk... Metastatic Mali... Metastatic Mela... Metastatic Muco... Metastatic Ocul... Pathologic Stag... | Ipilimumab Nivolumab Pembrolizumab Stereotactic Ra... Tumor Treating ... | 22 Years - | Emory University | |
Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma | NCT03604978 | Grade 2 Meningi... Grade 3 Meningi... Recurrent Menin... | Biospecimen Col... Echocardiograph... Ipilimumab Magnetic Resona... Nivolumab Stereotactic Ra... | 18 Years - | National Cancer Institute (NCI) | |
Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study | NCT04047602 | Brain Tumor Brain Metastase... Brain Cancer | Reduced Dose SR... | 18 Years - | Indiana University | |
Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme | NCT00004262 | Adult Giant Cel... Adult Glioblast... Adult Gliosarco... | conventional su... 3-dimensional c... stereotactic ra... motexafin gadol... magnetic resona... spectroscopy | 18 Years - | National Cancer Institute (NCI) | |
Pre-operative Stereotactic Radiosurgery Followed by Resection for Brain Metastases | NCT02514915 | Malignant Neopl... | Stereotactic Ra... | 18 Years - | University of Pittsburgh | |
Re-irradiation With Fractionated Stereotactic Radiosurgery Plus Cetuximab in Patients With Recurrent Squamous Cell Carcinoma of the Head and Neck | NCT01104922 | Squamous Cell C... | Cetuximab Stereotactic ra... | 18 Years - | University of Pittsburgh | |
Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases | NCT02858869 | Metastatic Mali... Metastatic Mela... Mucosal Melanom... Ocular Melanoma Stage IV Non-Sm... Stage IV Skin M... Melanoma of Unk... | Pembrolizumab Stereotactic Ra... | 18 Years - | Emory University | |
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability | NCT04804644 | Metastatic Lung... Metastatic Mali... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... | Memantine Hydro... Neurocognitive ... Stereotactic Ra... Whole-Brain Rad... | 18 Years - | NRG Oncology | |
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma | NCT05641441 | Vestibular Schw... Ototoxicity | Stereotactic ra... | 18 Years - | University Hospital, Geneva | |
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors | NCT03750227 | Malignant Solid... Metastatic Mali... | Conventional Su... Quality-of-Life... Questionnaire A... Stereotactic Ra... | 18 Years - | Mayo Clinic | |
18F ML-10 for Early Detection of Response of Brain Metastases to SRS | NCT00696943 | Metastasis to B... | ([18F]-ML-10) | 18 Years - | Aposense Ltd. | |
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery | NCT04588246 | Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ... | Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad... | 18 Years - | NRG Oncology | |
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC). | NCT02831959 | Brain Metastase... | NovoTTF-200M de... Best Standard o... | 18 Years - | NovoCure Ltd. | |
Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-100M for the Treatment of Melanoma Brain Metastases | NCT05341349 | Clinical Stage ... Melanoma of Unk... Metastatic Mali... Metastatic Mela... Metastatic Muco... Metastatic Ocul... Pathologic Stag... | Ipilimumab Nivolumab Pembrolizumab Stereotactic Ra... Tumor Treating ... | 22 Years - | Emory University | |
Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme | NCT00006386 | Brain and Centr... | carmustine radiation thera... stereotactic ra... | - | Radiation Therapy Oncology Group | |
Stereotactic Radiosurgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer | NCT00852644 | Lung Cancer | computed tomogr... fludeoxyglucose... hypofractionate... stereotactic ra... | 18 Years - | Boston Medical Center | |
Neoadjuvant Gemcitabine, Docetaxel, and Capecitabine in Combination With Stereotactic Radiosurgery | NCT00833859 | Pancreatic Neop... | GTX (gemcitabin... stereotactic bo... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG) | NCT05131711 | Recurrent Gliob... | Combined stereo... | 18 Years - 65 Years | Beijing Tiantan Hospital | |
A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases | NCT03368625 | Brain Metastase... | Stereotactic Ra... | 18 Years - | University Health Network, Toronto | |
Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases | NCT06248606 | Non Small Cell ... NSCLC KRAS G12C | Adagrasib Stereotactic Ra... | 18 Years - | Hoosier Cancer Research Network | |
SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine | NCT02716948 | Metastatic Mali... Metastatic Mali... Stage IV Skin M... | Laboratory Biom... Nivolumab Stereotactic Ra... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) | NCT03340129 | Melanoma Stage ... | Ipilimumab Nivolumab Stereotactic Ra... Salvage therapy | 18 Years - 120 Years | Melanoma Institute Australia | |
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery | NCT04588246 | Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ... | Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad... | 18 Years - | NRG Oncology | |
SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer | NCT04650490 | Brain Metastase... Non Small Cell ... | Stereotactic Ra... Immunotherapy | 18 Years - | Duke University | |
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas | NCT03956706 | Glioblastoma Astrocytoma, Gr... Astrocytoma, Gr... Malignant Gliom... | Stereotactic Ra... | 18 Years - | Northwell Health | |
Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer | NCT01622868 | HER2-Positive B... Invasive Breast... Metastatic Mali... Recurrent Breas... Stage IV Breast... | Laboratory Biom... Lapatinib Ditos... Stereotactic Ra... Whole-Brain Rad... | 18 Years - | National Cancer Institute (NCI) | |
Stereotactic Radiosurgery in Treating Patients With Brain Metastases | NCT00811655 | Metastatic Canc... Unspecified Adu... | therapeutic con... stereotactic ra... | 18 Years - | Duke University | |
Cognitive Outcome After Gamma Knife Radiosurgery in Patients With Brain Metastases (CAR-Study A) | NCT02953756 | Neoplasm Metast... | Gamma Knife rad... | 18 Years - | Elisabeth-TweeSteden Ziekenhuis | |
CyberKnife Radiosurgery for Organ-Confined Prostate Cancer: Homogenous Dose Distribution | NCT00643994 | Prostate Cancer Prostatic Cance... Prostate Neopla... Prostatic Neopl... Cancer of the P... | CyberKnife Ster... | 18 Years - | Accuray Incorporated | |
An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer | NCT06315296 | Anatomic Stage ... Metastatic Brea... Metastatic Lung... Metastatic Mali... Stage IV Lung C... | Behavioral Diet... Text Message-Ba... Internet-Based ... Dietary Counsel... Stereotactic Ra... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview Internet-Based ... Stereotactic Ra... Text Message-Ba... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview | 18 Years - | Thomas Jefferson University | |
Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma | NCT01378481 | Adult Anaplasti... Adult Anaplasti... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Adult Mixed Gli... Recurrent Adult... | Vorinostat Stereotactic Ra... Laboratory Biom... Pharmacological... Therapeutic Con... | 18 Years - | National Cancer Institute (NCI) | |
Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases | NCT05023772 | Neoplasm Metast... Spinal Cord Dis... Spinal Cord Com... Spinal Cord Tum... Spine Metastase... | Stereotactic La... Stereotactic Ra... MRI guided lase... | 18 Years - | Henry Ford Health System | |
Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases | NCT01843413 | Tumors Metastat... Unspecified Adu... | stereotactic ra... quality-of-life... cognitive asses... | 18 Years - | Case Comprehensive Cancer Center | |
Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal Metastases | NCT02387905 | Metastatic Mali... Metastatic Mali... | Management of T... Quality-of-Life... Questionnaire A... Stereotactic Ra... | 18 Years - | M.D. Anderson Cancer Center | |
Stereotactic Radiation Therapy in Treating Patients With Kidney Tumors | NCT00445757 | Kidney Cancer | conventional su... stereotactic ra... | 18 Years - | Case Comprehensive Cancer Center | |
Stereotactic Radiosurgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer | NCT00852644 | Lung Cancer | computed tomogr... fludeoxyglucose... hypofractionate... stereotactic ra... | 18 Years - | Boston Medical Center | |
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases | NCT00950001 | Metastatic Mali... | Stereotactic Ra... | 4 Years - | M.D. Anderson Cancer Center | |
Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC | NCT04147728 | Stereotactic Bo... | Anlotinib Stereotactic Ra... | 18 Years - 80 Years | Peking University Third Hospital | |
Stereotactic Radiation Therapy in Treating Patients With Brain Metastases | NCT00006259 | Metastatic Canc... | stereotactic ra... | 18 Years - 120 Years | Case Comprehensive Cancer Center | |
A Pilot Study of SBRT With Adjuvant Pazopanib for Renal Cell Cancer | NCT02307474 | Clear Cell Rena... Renal Cell Carc... | Stereotactic Ra... Pazopanib Hydro... | 18 Years - | Case Comprehensive Cancer Center | |
Radiation Therapy and Docetaxel Followed by Standard Therapy in Treating Women With Breast Cancer | NCT00872625 | Breast Cancer | cyclophosphamid... docetaxel epirubicin hydr... fluorouracil neoadjuvant the... therapeutic con... hypofractionate... image-guided ra... radiation thera... stereotactic ra... | 18 Years - | Centre Antoine Lacassagne | |
Evaluation of Stereotactic Radiosurgery For Liver Malignancies | NCT00230347 | Cholangiocarcin... Liver Cancer Adenocarcinoma | Stereotactic ra... | 18 Years - | Stanford University | |
Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by Surgery | NCT00104936 | Brain and Centr... | adjuvant therap... radiation thera... stereotactic ra... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
Neurocognitive Decline in Patients With Brain Metastases | NCT03508752 | Brain Metastase... | Stereotactic Ra... | 18 Years - | University of Texas Southwestern Medical Center | |
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery | NCT04689048 | Brain Metastase... Brain Metastase... Brain Cancer | 18F fluciclovin... | 18 Years - | Baptist Health South Florida | |
Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma | NCT00185861 | Brain Cancer | Arsenic Trioxid... Stereotactic ra... | 18 Years - | Stanford University | |
Stereotactic Radiosurgery for Patients With Hepatic Metastases. | NCT00547677 | Metastatic Canc... Unspecified Adu... | stereotactic ra... | 18 Years - 120 Years | University of Texas Southwestern Medical Center | |
An Outcome Analysis for Stereotactic Body Radiation Therapy (SBRT) Treatment of Non-Small Lung Cancer Patients Using 4D PET/CT With Real-Time Position Management (RPM™) System and a Concomitant Evaluation of the Impact and Performance Characteristics of the Immobilization System | NCT02067858 | Non Small Cell ... 4D CT | Stereotactic Ra... | 18 Years - | University of Pittsburgh | |
Dabrafenib and Trametinib With Radiosurgery in Melanoma Brain Mets | NCT01721603 | BRAFV600E Melan... | Dabrafenib Gamma Knife Rad... Trametinib | 18 Years - | University of California, San Francisco | |
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery | NCT03184038 | Metastatic Mali... Metastatic Mali... | Cognitive Asses... Stereotactic Ra... Stereotactic Bo... Quality-of-Life... | 18 Years - | Thomas Jefferson University | |
Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic Radiosurgery | NCT02097732 | Metastatic Mela... Brain Metastase... | Ipilimumab Stereotactic Ra... | 18 Years - | University of Michigan Rogel Cancer Center | |
Study of Temozolomide to Treat Newly Diagnosed Brain Metastases | NCT00717275 | Brain Metastase... | Temozolomide | 18 Years - | University of Florida | |
Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) | NCT03340129 | Melanoma Stage ... | Ipilimumab Nivolumab Stereotactic Ra... Salvage therapy | 18 Years - 120 Years | Melanoma Institute Australia | |
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC). | NCT02831959 | Brain Metastase... | NovoTTF-200M de... Best Standard o... | 18 Years - | NovoCure Ltd. | |
Evaluation of Truebeam for Low-Intermediate Risk Prostate Cancer | NCT01581749 | Prostate Neopla... | "TrueBeam" ster... | 21 Years - | Main Line Health | |
Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases | NCT03430947 | Malignant Melan... BRAF V600 Mutat... Brain Metastase... | Vemurafenib Cobimetinib | 18 Years - | Technische Universität Dresden | |
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER) | NCT04891471 | Neurocognitive ... Quality of Life Activities of D... | Stereotactic Ra... Whole Brain Irr... | 18 Years - | Mediterranean Institute of Oncology | |
A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases | NCT03497767 | Metastatic Non ... | Osimertinib Stereotactic Ra... | 18 Years - | Trans Tasman Radiation Oncology Group | |
Stereotactic Hypofractionated Radiosurgery for Early Stage Prostate Cancer | NCT00969202 | Prostate Cancer | Stereotactic Ra... | 18 Years - 99 Years | San Diego Radiosurgery | |
Stereotactic Radiosurgery With Sunitinib for Brain Metastases | NCT00981890 | Brain Metastase... | Sunitinib | 18 Years - | University Health Network, Toronto | |
Stereotactic Body Radiotherapy for Head and Neck Tumors | NCT01344356 | Squamous Cell C... Nasopharyngeal ... Salivary Gland ... Head and Neck S... Paraganglioma o... Chordoma of Hea... Chondrosarcoma ... Angiofibroma of... | stereotactic bo... Stereotactic bo... | 18 Years - | Mercy Research | |
Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases | NCT01644591 | Clinical Stage ... Metastatic Mali... Metastatic Mela... Pathologic Stag... | Quality-of-Life... Questionnaire A... Stereotactic Ra... | 18 Years - | M.D. Anderson Cancer Center | |
Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis | NCT04516070 | Metastatic Lung... Metastatic Mali... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... | Questionnaire A... Stereotactic Ra... | 18 Years - | M.D. Anderson Cancer Center | |
Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain Metastasis | NCT00484978 | Brain Neoplasms | Stereotactic Ra... | 18 Years - | Tel-Aviv Sourasky Medical Center | |
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases | NCT00950001 | Metastatic Mali... | Stereotactic Ra... | 4 Years - | M.D. Anderson Cancer Center | |
SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer | NCT04650490 | Brain Metastase... Non Small Cell ... | Stereotactic Ra... Immunotherapy | 18 Years - | Duke University | |
Evaluation of Truebeam for Low-Intermediate Risk Prostate Cancer | NCT01581749 | Prostate Neopla... | "TrueBeam" ster... | 21 Years - | Main Line Health | |
Stereotactic Radiosurgery With Sunitinib for Brain Metastases | NCT00981890 | Brain Metastase... | Sunitinib | 18 Years - | University Health Network, Toronto |