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Spots Global Cancer Trial Database for stereotactic radiosurgery

Every month we try and update this database with for stereotactic radiosurgery cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Stereotactic Radiation Therapy in Treating Patients With Prostate CancerNCT00619515
Prostate Cancer
questionnaire a...
implanted fiduc...
stereotactic ra...
- 120 YearsCase Comprehensive Cancer Center
Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)NCT05178472
Hematopoietic a...
Malignant Solid...
Metastatic Mali...
Immunotherapy
Stereotactic Ra...
Vertebroplasty
18 Years - Ohio State University Comprehensive Cancer Center
Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant GliomaNCT00185861
Brain Cancer
Arsenic Trioxid...
Stereotactic ra...
18 Years - Stanford University
Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain TumorsNCT00547131
Brain and Centr...
Metastatic Canc...
temozolomide
laboratory biom...
liquid chromato...
mass spectromet...
pharmacological...
conventional su...
stereotactic ra...
18 Years - 120 YearsCity of Hope Medical Center
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain MetastasesNCT00002708
Metastatic Canc...
surgical proced...
radiation thera...
stereotactic ra...
18 Years - Radiation Therapy Oncology Group
Hypofractionated Image Guided Radiation Therapy in Treating Patients With Stage IV Breast CancerNCT01706432
Central Nervous...
Invasive Ductal...
Invasive Ductal...
Invasive Lobula...
Invasive Lobula...
Liver Metastase...
Lobular Breast ...
Lung Metastases
Male Breast Can...
Medullary Ducta...
Mucinous Ductal...
Papillary Ducta...
Recurrent Breas...
Stage IV Breast...
Tubular Ductal ...
Tumors Metastat...
hyperfractionat...
laboratory biom...
stereotactic ra...
18 Years - University of Chicago
Stereotactic Radiosurgery Prognosis Assessment for Spinal Tumors Based on RadiomicsNCT05369689
Stereotactic Ra...
Spinal Tumor
Radiomics
Prognosis
No intervention...
18 Years - 80 YearsPeking University Third Hospital
Stereotactic Radiation in Vestibular SchwannomaNCT01449604
Vestibular Schw...
stereotactic ra...
stereotactic ra...
18 Years - 80 YearsRamathibodi Hospital
Stereotactic Radiosurgery in Treating Patients With Brain MetastasesNCT00811655
Metastatic Canc...
Unspecified Adu...
therapeutic con...
stereotactic ra...
18 Years - Duke University
A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain MetastasesNCT03497767
Metastatic Non ...
Osimertinib
Stereotactic Ra...
18 Years - Trans Tasman Radiation Oncology Group
Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-100M for the Treatment of Melanoma Brain MetastasesNCT05341349
Clinical Stage ...
Melanoma of Unk...
Metastatic Mali...
Metastatic Mela...
Metastatic Muco...
Metastatic Ocul...
Pathologic Stag...
Ipilimumab
Nivolumab
Pembrolizumab
Stereotactic Ra...
Tumor Treating ...
22 Years - Emory University
Stereotactic Radiosurgery (SRS) for Multiple CNS MetsNCT02567643
Metastatic Canc...
Brain Metastase...
Stereotactic Ra...
- The Cooper Health System
Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III MeningiomaNCT03604978
Grade 2 Meningi...
Grade 3 Meningi...
Recurrent Menin...
Biospecimen Col...
Echocardiograph...
Ipilimumab
Magnetic Resona...
Nivolumab
Stereotactic Ra...
18 Years - National Cancer Institute (NCI)
Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot StudyNCT04047602
Brain Tumor
Brain Metastase...
Brain Cancer
Reduced Dose SR...
18 Years - Indiana University
Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma MultiformeNCT00004262
Adult Giant Cel...
Adult Glioblast...
Adult Gliosarco...
conventional su...
3-dimensional c...
stereotactic ra...
motexafin gadol...
magnetic resona...
spectroscopy
18 Years - National Cancer Institute (NCI)
Pre-operative Stereotactic Radiosurgery Followed by Resection for Brain MetastasesNCT02514915
Malignant Neopl...
Stereotactic Ra...
18 Years - University of Pittsburgh
Re-irradiation With Fractionated Stereotactic Radiosurgery Plus Cetuximab in Patients With Recurrent Squamous Cell Carcinoma of the Head and NeckNCT01104922
Squamous Cell C...
Cetuximab
Stereotactic ra...
18 Years - University of Pittsburgh
Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain MetastasesNCT02858869
Metastatic Mali...
Metastatic Mela...
Mucosal Melanom...
Ocular Melanoma
Stage IV Non-Sm...
Stage IV Skin M...
Melanoma of Unk...
Pembrolizumab
Stereotactic Ra...
18 Years - Emory University
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking AbilityNCT04804644
Metastatic Lung...
Metastatic Mali...
Recurrent Lung ...
Stage IV Lung C...
Stage IVA Lung ...
Stage IVB Lung ...
Memantine Hydro...
Neurocognitive ...
Stereotactic Ra...
Whole-Brain Rad...
18 Years - NRG Oncology
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular SchwannomaNCT05641441
Vestibular Schw...
Ototoxicity
Stereotactic ra...
18 Years - University Hospital, Geneva
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain TumorsNCT03750227
Malignant Solid...
Metastatic Mali...
Conventional Su...
Quality-of-Life...
Questionnaire A...
Stereotactic Ra...
18 Years - Mayo Clinic
18F ML-10 for Early Detection of Response of Brain Metastases to SRSNCT00696943
Metastasis to B...
([18F]-ML-10)
18 Years - Aposense Ltd.
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic RadiosurgeryNCT04588246
Anatomic Stage ...
Metastatic Brea...
Metastatic Dige...
Metastatic Lung...
Metastatic Mali...
Metastatic Mela...
Metastatic Rena...
Prognostic Stag...
Recurrent Brain...
Stage IV Lung C...
Stage IV Renal ...
Stage IVA Lung ...
Stage IVB Lung ...
Memantine
Quality-of-Life...
Questionnaire A...
Stereotactic Ra...
Whole-Brain Rad...
18 Years - NRG Oncology
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).NCT02831959
Brain Metastase...
NovoTTF-200M de...
Best Standard o...
18 Years - NovoCure Ltd.
Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-100M for the Treatment of Melanoma Brain MetastasesNCT05341349
Clinical Stage ...
Melanoma of Unk...
Metastatic Mali...
Metastatic Mela...
Metastatic Muco...
Metastatic Ocul...
Pathologic Stag...
Ipilimumab
Nivolumab
Pembrolizumab
Stereotactic Ra...
Tumor Treating ...
22 Years - Emory University
Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma MultiformeNCT00006386
Brain and Centr...
carmustine
radiation thera...
stereotactic ra...
- Radiation Therapy Oncology Group
Stereotactic Radiosurgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung CancerNCT00852644
Lung Cancer
computed tomogr...
fludeoxyglucose...
hypofractionate...
stereotactic ra...
18 Years - Boston Medical Center
Neoadjuvant Gemcitabine, Docetaxel, and Capecitabine in Combination With Stereotactic RadiosurgeryNCT00833859
Pancreatic Neop...
GTX (gemcitabin...
stereotactic bo...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG)NCT05131711
Recurrent Gliob...
Combined stereo...
18 Years - 65 YearsBeijing Tiantan Hospital
A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain MetastasesNCT03368625
Brain Metastase...
Stereotactic Ra...
18 Years - University Health Network, Toronto
Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain MetastasesNCT06248606
Non Small Cell ...
NSCLC
KRAS G12C
Adagrasib
Stereotactic Ra...
18 Years - Hoosier Cancer Research Network
SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or SpineNCT02716948
Metastatic Mali...
Metastatic Mali...
Stage IV Skin M...
Laboratory Biom...
Nivolumab
Stereotactic Ra...
18 Years - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study)NCT03340129
Melanoma Stage ...
Ipilimumab
Nivolumab
Stereotactic Ra...
Salvage therapy
18 Years - 120 YearsMelanoma Institute Australia
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic RadiosurgeryNCT04588246
Anatomic Stage ...
Metastatic Brea...
Metastatic Dige...
Metastatic Lung...
Metastatic Mali...
Metastatic Mela...
Metastatic Rena...
Prognostic Stag...
Recurrent Brain...
Stage IV Lung C...
Stage IV Renal ...
Stage IVA Lung ...
Stage IVB Lung ...
Memantine
Quality-of-Life...
Questionnaire A...
Stereotactic Ra...
Whole-Brain Rad...
18 Years - NRG Oncology
SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung CancerNCT04650490
Brain Metastase...
Non Small Cell ...
Stereotactic Ra...
Immunotherapy
18 Years - Duke University
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant GliomasNCT03956706
Glioblastoma
Astrocytoma, Gr...
Astrocytoma, Gr...
Malignant Gliom...
Stereotactic Ra...
18 Years - Northwell Health
Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast CancerNCT01622868
HER2-Positive B...
Invasive Breast...
Metastatic Mali...
Recurrent Breas...
Stage IV Breast...
Laboratory Biom...
Lapatinib Ditos...
Stereotactic Ra...
Whole-Brain Rad...
18 Years - National Cancer Institute (NCI)
Stereotactic Radiosurgery in Treating Patients With Brain MetastasesNCT00811655
Metastatic Canc...
Unspecified Adu...
therapeutic con...
stereotactic ra...
18 Years - Duke University
Cognitive Outcome After Gamma Knife Radiosurgery in Patients With Brain Metastases (CAR-Study A)NCT02953756
Neoplasm Metast...
Gamma Knife rad...
18 Years - Elisabeth-TweeSteden Ziekenhuis
CyberKnife Radiosurgery for Organ-Confined Prostate Cancer: Homogenous Dose DistributionNCT00643994
Prostate Cancer
Prostatic Cance...
Prostate Neopla...
Prostatic Neopl...
Cancer of the P...
CyberKnife Ster...
18 Years - Accuray Incorporated
An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung CancerNCT06315296
Anatomic Stage ...
Metastatic Brea...
Metastatic Lung...
Metastatic Mali...
Stage IV Lung C...
Behavioral Diet...
Text Message-Ba...
Internet-Based ...
Dietary Counsel...
Stereotactic Ra...
Biospecimen Col...
Magnetic Resona...
Neurocognitive ...
Questionnaire A...
Interview
Internet-Based ...
Stereotactic Ra...
Text Message-Ba...
Biospecimen Col...
Magnetic Resona...
Neurocognitive ...
Questionnaire A...
Interview
18 Years - Thomas Jefferson University
Stereotactic Radiosurgery (SRS) for Multiple CNS MetsNCT02567643
Metastatic Canc...
Brain Metastase...
Stereotactic Ra...
- The Cooper Health System
High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent GliomaNCT01378481
Adult Anaplasti...
Adult Anaplasti...
Adult Giant Cel...
Adult Glioblast...
Adult Gliosarco...
Adult Mixed Gli...
Recurrent Adult...
Vorinostat
Stereotactic Ra...
Laboratory Biom...
Pharmacological...
Therapeutic Con...
18 Years - National Cancer Institute (NCI)
Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine MetastasesNCT05023772
Neoplasm Metast...
Spinal Cord Dis...
Spinal Cord Com...
Spinal Cord Tum...
Spine Metastase...
Stereotactic La...
Stereotactic Ra...
MRI guided lase...
18 Years - Henry Ford Health System
Stereotactic Radiosurgery in Treating Patients With Large Brain MetastasesNCT01843413
Tumors Metastat...
Unspecified Adu...
stereotactic ra...
quality-of-life...
cognitive asses...
18 Years - Case Comprehensive Cancer Center
Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal MetastasesNCT02387905
Metastatic Mali...
Metastatic Mali...
Management of T...
Quality-of-Life...
Questionnaire A...
Stereotactic Ra...
18 Years - M.D. Anderson Cancer Center
Stereotactic Radiation Therapy in Treating Patients With Kidney TumorsNCT00445757
Kidney Cancer
conventional su...
stereotactic ra...
18 Years - Case Comprehensive Cancer Center
Stereotactic Radiosurgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung CancerNCT00852644
Lung Cancer
computed tomogr...
fludeoxyglucose...
hypofractionate...
stereotactic ra...
18 Years - Boston Medical Center
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain MetastasesNCT00950001
Metastatic Mali...
Stereotactic Ra...
4 Years - M.D. Anderson Cancer Center
Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLCNCT04147728
Stereotactic Bo...
Anlotinib
Stereotactic Ra...
18 Years - 80 YearsPeking University Third Hospital
Stereotactic Radiation Therapy in Treating Patients With Brain MetastasesNCT00006259
Metastatic Canc...
stereotactic ra...
18 Years - 120 YearsCase Comprehensive Cancer Center
A Pilot Study of SBRT With Adjuvant Pazopanib for Renal Cell CancerNCT02307474
Clear Cell Rena...
Renal Cell Carc...
Stereotactic Ra...
Pazopanib Hydro...
18 Years - Case Comprehensive Cancer Center
Radiation Therapy and Docetaxel Followed by Standard Therapy in Treating Women With Breast CancerNCT00872625
Breast Cancer
cyclophosphamid...
docetaxel
epirubicin hydr...
fluorouracil
neoadjuvant the...
therapeutic con...
hypofractionate...
image-guided ra...
radiation thera...
stereotactic ra...
18 Years - Centre Antoine Lacassagne
Evaluation of Stereotactic Radiosurgery For Liver MalignanciesNCT00230347
Cholangiocarcin...
Liver Cancer
Adenocarcinoma
Stereotactic ra...
18 Years - Stanford University
Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by SurgeryNCT00104936
Brain and Centr...
adjuvant therap...
radiation thera...
stereotactic ra...
18 Years - European Organisation for Research and Treatment of Cancer - EORTC
Neurocognitive Decline in Patients With Brain MetastasesNCT03508752
Brain Metastase...
Stereotactic Ra...
18 Years - University of Texas Southwestern Medical Center
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic RadiosurgeryNCT04689048
Brain Metastase...
Brain Metastase...
Brain Cancer
18F fluciclovin...
18 Years - Baptist Health South Florida
Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant GliomaNCT00185861
Brain Cancer
Arsenic Trioxid...
Stereotactic ra...
18 Years - Stanford University
Stereotactic Radiosurgery for Patients With Hepatic Metastases.NCT00547677
Metastatic Canc...
Unspecified Adu...
stereotactic ra...
18 Years - 120 YearsUniversity of Texas Southwestern Medical Center
An Outcome Analysis for Stereotactic Body Radiation Therapy (SBRT) Treatment of Non-Small Lung Cancer Patients Using 4D PET/CT With Real-Time Position Management (RPM™) System and a Concomitant Evaluation of the Impact and Performance Characteristics of the Immobilization SystemNCT02067858
Non Small Cell ...
4D CT
Stereotactic Ra...
18 Years - University of Pittsburgh
Dabrafenib and Trametinib With Radiosurgery in Melanoma Brain MetsNCT01721603
BRAFV600E Melan...
Dabrafenib
Gamma Knife Rad...
Trametinib
18 Years - University of California, San Francisco
Neurocognition in Patients With Multiple Brain Metastases Treated With RadiosurgeryNCT03184038
Metastatic Mali...
Metastatic Mali...
Cognitive Asses...
Stereotactic Ra...
Stereotactic Bo...
Quality-of-Life...
18 Years - Thomas Jefferson University
Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic RadiosurgeryNCT02097732
Metastatic Mela...
Brain Metastase...
Ipilimumab
Stereotactic Ra...
18 Years - University of Michigan Rogel Cancer Center
Study of Temozolomide to Treat Newly Diagnosed Brain MetastasesNCT00717275
Brain Metastase...
Temozolomide
18 Years - University of Florida
Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study)NCT03340129
Melanoma Stage ...
Ipilimumab
Nivolumab
Stereotactic Ra...
Salvage therapy
18 Years - 120 YearsMelanoma Institute Australia
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).NCT02831959
Brain Metastase...
NovoTTF-200M de...
Best Standard o...
18 Years - NovoCure Ltd.
Evaluation of Truebeam for Low-Intermediate Risk Prostate CancerNCT01581749
Prostate Neopla...
"TrueBeam" ster...
21 Years - Main Line Health
Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain MetastasesNCT03430947
Malignant Melan...
BRAF V600 Mutat...
Brain Metastase...
Vemurafenib
Cobimetinib
18 Years - Technische Universität Dresden
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)NCT04891471
Neurocognitive ...
Quality of Life
Activities of D...
Stereotactic Ra...
Whole Brain Irr...
18 Years - Mediterranean Institute of Oncology
A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain MetastasesNCT03497767
Metastatic Non ...
Osimertinib
Stereotactic Ra...
18 Years - Trans Tasman Radiation Oncology Group
Stereotactic Hypofractionated Radiosurgery for Early Stage Prostate CancerNCT00969202
Prostate Cancer
Stereotactic Ra...
18 Years - 99 YearsSan Diego Radiosurgery
Stereotactic Radiosurgery With Sunitinib for Brain MetastasesNCT00981890
Brain Metastase...
Sunitinib
18 Years - University Health Network, Toronto
Stereotactic Body Radiotherapy for Head and Neck TumorsNCT01344356
Squamous Cell C...
Nasopharyngeal ...
Salivary Gland ...
Head and Neck S...
Paraganglioma o...
Chordoma of Hea...
Chondrosarcoma ...
Angiofibroma of...
stereotactic bo...
Stereotactic bo...
18 Years - Mercy Research
Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain MetastasesNCT01644591
Clinical Stage ...
Metastatic Mali...
Metastatic Mela...
Pathologic Stag...
Quality-of-Life...
Questionnaire A...
Stereotactic Ra...
18 Years - M.D. Anderson Cancer Center
Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain MetastasisNCT04516070
Metastatic Lung...
Metastatic Mali...
Stage IV Lung C...
Stage IVA Lung ...
Stage IVB Lung ...
Questionnaire A...
Stereotactic Ra...
18 Years - M.D. Anderson Cancer Center
Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain MetastasisNCT00484978
Brain Neoplasms
Stereotactic Ra...
18 Years - Tel-Aviv Sourasky Medical Center
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain MetastasesNCT00950001
Metastatic Mali...
Stereotactic Ra...
4 Years - M.D. Anderson Cancer Center
SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung CancerNCT04650490
Brain Metastase...
Non Small Cell ...
Stereotactic Ra...
Immunotherapy
18 Years - Duke University
Evaluation of Truebeam for Low-Intermediate Risk Prostate CancerNCT01581749
Prostate Neopla...
"TrueBeam" ster...
21 Years - Main Line Health
Stereotactic Radiosurgery With Sunitinib for Brain MetastasesNCT00981890
Brain Metastase...
Sunitinib
18 Years - University Health Network, Toronto
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