Spots Global Cancer Trial Database for Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab
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Trial Identification
Brief Title: Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab
Official Title: Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab
Study ID: NCT04961307
Interventions
Study Description
Brief Summary: By dynamically observing the changes of echocardiogram and biomarkers in breast cancer patients using trastuzumab, evaluate the effect of trastuzumab on cardiac function; determine the sensitivity of echocardiography and biomarker indicators And specificity, explore effective and specific early warning indicators, and provide technical support for the evaluation of the cardiac safety of anti-tumor drugs.
Detailed Description: Thirty female breast cancer patients using trastuzumab, collected demographic and clinical information of all patients before chemotherapy, performed echocardiography (conventional echocardiography, three-dimensional spot tracking technology), and collected blood samples to detect plasma biology Markers (TnT, BNP, GDF-15, topoisomerase), follow-up echocardiography and biomarkers at 1 month, 3 months and 6 months after chemotherapy.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Peking University Third Hospital, Peking, Beijing, China
Contact Details
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