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Brief Title: The p53 Colorectal Cancer Trial
Official Title: Treatment of Patients With Metastatic Colorectal Cancer Harboring TP53 Mutations With Dose-dense Cyclophosphamide - the p53 Colorectal Cancer Trial
Study ID: NCT03149679
Brief Summary: Single center, open labeled, phase 2 clinical trial, where patients with metastatic colorectal cancer are selected for treatment with dose dense Cyclophosphamide every second week based on TP53 mutation status; i.e. only patients with TP53 mutated tumors may be included in the treatment arm.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Haukeland University Hospital, Bergen, , Norway
Name: Inger Marie Løes, MD PhD
Affiliation: Haukeland University Hospital
Role: PRINCIPAL_INVESTIGATOR