Spots Global Cancer Trial Database for colorectal cancer stage iv
Every month we try and update this database with for colorectal cancer stage iv cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis | NCT04157322 | Colorectal Canc... Colorectal Canc... Colorectal Canc... Appendix Cancer | prospective sin... | 18 Years - | University of Chicago | |
| Adjuvant Durvalumab Plus Regorafenib vs Untreated Control in Stage IV Colorectal Cancer Patients With no Evidence of Disease (NED): VIVA Trial | NCT05382741 | Colorectal Canc... No Evidence of ... | Durvalumab Inje... Regorafenib 30 ... | 18 Years - | Ospedale Policlinico San Martino | |
| AREG, EREG and EGFR: Response to Anti-EGFR Agents in Colorectal Cancer | NCT03986541 | Colorectal Canc... | Immunohistochem... | 18 Years - | University of Leeds | |
| Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory | NCT05576896 | Stage IV Colore... Colorectal Canc... Colorectal Canc... | Hydroxychloroqu... | 18 Years - | Northwestern University | |
| Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer | NCT05426005 | Colorectal Canc... Mismatch Repair... Microsatellite ... | Cadonilimab | 18 Years - | Sun Yat-sen University | |
| Matrilysin Expression in Different Stages of Colorectal Tumors | NCT01570452 | Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... | colonic or colo... | 40 Years - 83 Years | University of Roma La Sapienza | |
| Early Onset Colorectal Cancer Detection | NCT06342401 | Colorectal Canc... Colorectal Neop... Colorectal Aden... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Neop... | ENCODE | 18 Years - 50 Years | City of Hope Medical Center | |
| Prognostic Impact of Increased Lymph Node Yield in Colorectal Cancer Patients With Synchronous Distant Metastasis: a Population-based Study of the US Database and a Chinese Registry | NCT05550701 | Colorectal Canc... Lymph Node Yiel... | lymph node yiel... | 18 Years - 90 Years | The Second Affiliated Hospital of Harbin Medical University | |
| Prognostic Impact of Increased Lymph Node Yield in Colorectal Cancer Patients With Synchronous Distant Metastasis: a Population-based Study of the US Database and a Chinese Registry | NCT05550701 | Colorectal Canc... Lymph Node Yiel... | lymph node yiel... | 18 Years - 90 Years | The Second Affiliated Hospital of Harbin Medical University | |
| Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin | NCT05354817 | Colorectal Canc... | mFOLFIRINOX | 18 Years - 70 Years | Instituto do Cancer do Estado de São Paulo | |
| Early Onset Colorectal Cancer Detection | NCT06342401 | Colorectal Canc... Colorectal Neop... Colorectal Aden... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Neop... | ENCODE | 18 Years - 50 Years | City of Hope Medical Center | |
| Early Onset Colorectal Cancer Detection | NCT06342401 | Colorectal Canc... Colorectal Neop... Colorectal Aden... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Neop... | ENCODE | 18 Years - 50 Years | City of Hope Medical Center | |
| Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer | NCT05426005 | Colorectal Canc... Mismatch Repair... Microsatellite ... | Cadonilimab | 18 Years - | Sun Yat-sen University | |
| Phase I Study of Combined Immune Cell Therapy in Patients With Stage 4 Colorectal Cancer With Metastatic Lesion Who Failed Prior Standard of Care | NCT06296056 | Colorectal Canc... Metastatic Colo... | Combi | 19 Years - | Seoul Hospital | |
| Treatment Response Prediction System of mCRC Patients Based on CTC | NCT04917276 | Colorectal Canc... Circulating Tum... | Circulating tum... | 18 Years - 80 Years | Fudan University | |
| The p53 Colorectal Cancer Trial | NCT03149679 | Colorectal Canc... Colorectal Canc... TP53 Gene Mutat... | Cyclophosphamid... | 18 Years - | Haukeland University Hospital | |
| Parenchymal Sparing Hepatectomy in Post-chemotherapy Liver Atrophy | NCT06329700 | Colorectal Canc... | Hepatectomy | 18 Years - | Azienda Ospedaliero Universitaria Maggiore della Carita | |
| Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer | NCT04425239 | Colorectal Canc... | Panitumumab Panitumumab | 18 Years - | National Cancer Institute, Naples | |
| Impact of Aerobic Exercise on Immune Response and Side Effects of Cancer Treatments | NCT04715061 | Colorectal Canc... | Resting state (... Moderate Intens... High Intensity ... | 50 Years - 65 Years | Université de Sherbrooke | |
| Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer | NCT04425239 | Colorectal Canc... | Panitumumab Panitumumab | 18 Years - | National Cancer Institute, Naples | |
| Mechanisms of Fate Evolution of Colorectal Adenocarcinoma Metastasis | NCT04714814 | Colorectal Canc... Colorectal Canc... | 18 Years - 75 Years | Shanghai Minimally Invasive Surgery Center | ||
| Early Detection of Advanced Adenomas and Colorectal Cancer | NCT06342440 | Colorectal Canc... Colorectal Neop... Colorectal Poly... Colorectal Aden... Colorectal Diso... Colorectal Dysp... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Neop... Colorectal Serr... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... | DENEB | 18 Years - | City of Hope Medical Center | |
| Early Detection of Advanced Adenomas and Colorectal Cancer | NCT06342440 | Colorectal Canc... Colorectal Neop... Colorectal Poly... Colorectal Aden... Colorectal Diso... Colorectal Dysp... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Neop... Colorectal Serr... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... | DENEB | 18 Years - | City of Hope Medical Center | |
| Study on the Prevention of Dermal Toxicity Caused by Regorafenib by Traditional Chinese Medicine TDX105 | NCT05289726 | Hand and Foot S... Colorectal Canc... | Traditional chi... Placebo | 18 Years - | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Mechanisms of Fate Evolution of Colorectal Adenocarcinoma Metastasis | NCT04714814 | Colorectal Canc... Colorectal Canc... | 18 Years - 75 Years | Shanghai Minimally Invasive Surgery Center | ||
| Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis | NCT04157322 | Colorectal Canc... Colorectal Canc... Colorectal Canc... Appendix Cancer | prospective sin... | 18 Years - | University of Chicago | |
| Early Detection of Advanced Adenomas and Colorectal Cancer | NCT06342440 | Colorectal Canc... Colorectal Neop... Colorectal Poly... Colorectal Aden... Colorectal Diso... Colorectal Dysp... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Canc... Colorectal Neop... Colorectal Serr... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... Colorectal Aden... | DENEB | 18 Years - | City of Hope Medical Center | |
| Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory | NCT05576896 | Stage IV Colore... Colorectal Canc... Colorectal Canc... | Hydroxychloroqu... | 18 Years - | Northwestern University | |
| Predictive and Prognostic Value of Inflammatory Markers and microRNA in Stage IV Colorectal Cancer | NCT04149613 | Colorectal Canc... | 18 Years - | American University of Beirut Medical Center | ||
| Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer | NCT04425239 | Colorectal Canc... | Panitumumab Panitumumab | 18 Years - | National Cancer Institute, Naples | |
| Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin | NCT05354817 | Colorectal Canc... | mFOLFIRINOX | 18 Years - 70 Years | Instituto do Cancer do Estado de São Paulo | |
| Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis | NCT04157322 | Colorectal Canc... Colorectal Canc... Colorectal Canc... Appendix Cancer | prospective sin... | 18 Years - | University of Chicago | |
| Prognostic Impact of Increased Lymph Node Yield in Colorectal Cancer Patients With Synchronous Distant Metastasis: a Population-based Study of the US Database and a Chinese Registry | NCT05550701 | Colorectal Canc... Lymph Node Yiel... | lymph node yiel... | 18 Years - 90 Years | The Second Affiliated Hospital of Harbin Medical University | |
| Detection of MSI in Circulating Tumor DNA of Colorectal Carcinoma Patients | NCT03594448 | Microsatellite ... Colorectal Canc... | Specimen Collec... Serial Liquid B... | 18 Years - | University of Southern California | |
| Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer | NCT05171660 | Colorectal Canc... | Sintilimab Inje... Control Test | 18 Years - 75 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University |
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