Spots Global Cancer Trial Database for A Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors
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Trial Identification
Brief Title: A Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors
Official Title: A Phase 1 Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors
Study ID: NCT05571839
Interventions
Study Description
Brief Summary: This study will test the safety of a drug called SGN-BB228 in participants with melanoma and other solid tumors that are hard to treat or have spread through the body. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. This study will have 3 parts. Parts A and B of the study will find out how much SGN-BB228 should be given to participants. Part C will use the information from Parts A and B to see if SGN-BB228 is safe and if it works to treat solid tumor cancers.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of California Los Angeles Medical Center, Los Angeles, California, United States
University of California, San Francisco | HDFCCC - Hematopoietic Malignancies, San Francisco, California, United States
Sarah Cannon Research Institute at HealthONE - Denver, Denver, Colorado, United States
Northwestern University, Chicago, Illinois, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
NYU Langone Hospital, New York, New York, United States
Duke University Medical Center, Durham, North Carolina, United States
Texas Oncology - Baylor Sammons Cancer Center, Dallas, Texas, United States
Fred Hutchinson Cancer Center / Seattle Cancer Care Alliance / University of Washington, Seattle, Washington, United States
Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada
University Health Network, Princess Margaret Hospital, Toronto, Other, Canada
Jewish General Hospital, Montreal, Quebec, Canada
Institut Gustave Roussy, Villejuif Cedex, Other, France
Charite Universitatsmedizin Berlin, Berlin, Other, Germany
Universitatsspital Zurich, Zurich, Other, Switzerland
NHS Greater Glasgow and Clyde (NHSGGC) - The Beatson West of Scotland Cancer Centre, Glasgow, Other, United Kingdom
Contact Details
Name: Medical Monitor
Affiliation: Seagen Inc.
Role: STUDY_DIRECTOR
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