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Spots Global Cancer Trial Database for cutaneous melanoma

Every month we try and update this database with for cutaneous melanoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
A Study of SGN-BB228 in Advanced Melanoma and Other Solid TumorsNCT05571839
Cutaneous Melan...
Non-small Cell ...
Colorectal Neop...
Pancreatic Neop...
Mesothelioma
SGN-BB228
18 Years - Seagen Inc.
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)NCT05549297
Advanced Melano...
Tebentafusp
Tebentafusp wit...
Investigators C...
18 Years - Immunocore Ltd
A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)NCT06346067
Advanced or Met...
Naporafenib
Dacarbazine
Temozolomide
Trametinib
18 Years - 99 YearsErasca, Inc.
PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous MelanomaNCT02288897
Cutaneous Melan...
PV-10 (10% rose...
Dacarbazine, te...
18 Years - Provectus Pharmaceuticals
Evaluation of Ultrasound Biomicroscopy in the Local Staging of Cutaneous MelanomaNCT04702854
Cutaneous Melan...
Ultrasound Biom...
18 Years - Centre Hospitalier Universitaire de Nice
A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive MelanomasNCT04551352
Cutaneous Melan...
Uveal Melanoma
Mucosal Melanom...
RO7293583
Tocilizumab
Obinutuzumab
Adalimumab
18 Years - Hoffmann-La Roche
Neoadjuvant Atezolizumab in Cutaneous MelanomaNCT04020809
Cutaneous Melan...
Atezolizumab
18 Years - The Methodist Hospital Research Institute
Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and BinimetinibNCT03235245
Unresectable St...
Stage IV Melano...
Nivolumab + Ipi...
Encorafenib + B...
18 Years - European Organisation for Research and Treatment of Cancer - EORTC
Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk MelanomaNCT06319196
Cutaneous Melan...
Melanoma Stage ...
Mucosal Melanom...
Opdualag
Nivolumab
18 Years - University Health Network, Toronto
A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced CancersNCT05544929
Carcinoma, Non-...
Cutaneous Melan...
Carcinoma, Rena...
Carcinoma, Ovar...
Nasopharyngeal ...
Carcinoma, Thym...
Anal Cancer
Mesothelioma
Esophagogastric...
High Microsatel...
Squamous Cell C...
Triple Negative...
KFA115
pembrolizumab
18 Years - Novartis
Evaluation of the Impact of Adjuvants Accompanying Peptide Immunization in High-Risk MelanomaNCT00273910
High-Risk Melan...
gp100:209-217 (...
Montanide ISA-5...
Imiquimod
7 Years - National Institutes of Health Clinical Center (CC)
Expanded Access Program of Lifileucel (LN-144) in Patients With Unresectable or Metastatic MelanomaNCT05398640
Unresectable Me...
Metastatic Mela...
Lifileucel
18 Years - Iovance Biotherapeutics, Inc.
miRNA Machinery in Melanoma, Melanoma Metastases and Benign Melanocytic NaeviNCT01444560
Cutaneous Melan...
Nevi
1 Year - Ruhr University of Bochum
Sonazoid-Enhanced Ultrasound in Detecting Sentinel Lymph Node in Patients With Cutaneous MelanomaNCT02968680
Cutaneous Melan...
Melanoma
Sentinel Lymph ...
Ultrasonography
Sonazoid
19 Years - University of Southern California
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing TumorsNCT05283330
Cervical Cancer
Prostate Cancer...
Breast Cancer
Colon Cancer
NSCLC
Cutaneous Melan...
²¹²Pb-DOTAM-GRP...
18 Years - Orano Med LLC
A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)NCT06346067
Advanced or Met...
Naporafenib
Dacarbazine
Temozolomide
Trametinib
18 Years - 99 YearsErasca, Inc.
Exercise to Boost Response to Checkpoint Blockade ImmunotherapyNCT05358938
Cutaneous Melan...
Cutaneous Squam...
Merkel Cell Car...
Exercise
Checkpoint Bloc...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Advanced Non-invasive Diagnostics for Early Cutaneous Tumor Diagnosis, Clinical-therapeutic and Economic ManagementNCT04789421
Cutaneous Melan...
Clinical, dermo...
Clinical, dermo...
18 Years - Azienda Ospedaliero-Universitaria di Modena
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid TumorsNCT05970497
Cancer
Melanoma Stage ...
Melanoma Stage ...
Cutaneous Melan...
Osteosarcoma
Carcinoma, Squa...
Carcinoma, Basa...
KB707
18 Years - Krystal Biotech, Inc.
A Beta-only IL-2 ImmunoTherapY StudyNCT05086692
Advanced Solid ...
Unresectable So...
Clear Cell Rena...
Triple Negative...
Non-Small Cell ...
Non-Small Cell ...
Colorectal Canc...
Gastric Cancer
Cervical Cancer
Basal Cell Carc...
Bladder Cancer
Merkel Cell Car...
Squamous Cell C...
Cutaneous Squam...
Pleural Mesothe...
Esophageal Canc...
Endometrial Car...
Solid Tumor
Solid Tumor, Ad...
MSI-H Solid Mal...
Cancer With A H...
Epithelial Ovar...
Primary Periton...
Gastroesophagea...
Acral Melanoma
Mucosal Melanom...
Cutaneous Melan...
DMMR Solid Mali...
Fallopian Tube ...
Ovarian Cancer
MSI-H Cancer
DMMR Cancer
Pancreas Adenoc...
Skin Cancer
MDNA11
Pembrolizumab
18 Years - Medicenna Therapeutics, Inc.
A Safety Study of SEA-TGT (SGN-TGT) in Advanced CancerNCT04254107
Non-small Cell ...
Gastric Carcino...
Gastroesophagea...
Classical Hodgk...
Diffuse Large B...
Peripheral T-ce...
Cutaneous Melan...
Head and Neck S...
Bladder Cancer
Ovarian Cancer
Triple Negative...
Cervical Cancer
SEA-TGT
sasanlimab
brentuximab ved...
18 Years - Seagen Inc.
Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney CancerNCT00328861
Metastatic Mela...
Metastatic Kidn...
Natural Killer ...
IL-2
Cyclophosphamid...
Fludarabine
18 Years - National Institutes of Health Clinical Center (CC)
Validation of Ferromagnetic Tracer in Melanoma Sentinel NodeNCT03449615
Melanoma Stage
Sentinel Lymph ...
18 Years - Sociedad Española de Oncología Quirúrgica
A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid TumorsNCT02988960
Advanced Solid ...
ABBV-927
ABBV-927
ABBV-181
18 Years - AbbVie
The MELAcare Study: A New Method for Surveillance of Melanoma PatientsNCT05253872
Cutaneous Melan...
The MelaCare in...
18 Years - Herlev and Gentofte Hospital
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin CancersNCT06223659
Cutaneous Melan...
Merkel Cell Car...
Skin Squamous C...
Eutectic Mixtur...
Placebo Adminis...
Questionnaire A...
18 Years - 99 YearsOhio State University Comprehensive Cancer Center
4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 TherapyNCT03278665
Malignant Melan...
4SC-202 in comb...
18 Years - 4SC AG
Phase II Study of KW2871 Combined With High Dose Interferon-α2b in Patients With Metastatic MelanomaNCT00679289
Metastatic Mela...
Cutaneous Melan...
HDI
KW2871
KW2871
KW2871
18 Years - Ludwig Institute for Cancer Research
Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With MelanomaNCT02447939
Melanoma
Dabrafenib
Trametinib
18 Years - GlaxoSmithKline
Neoadjuvant and Adjuvant Checkpoint BlockadeNCT02519322
Cutaneous Melan...
Mucosal Melanom...
Ocular Melanoma
Stage III Acral...
Stage IIIB Cuta...
Stage IIIB Uvea...
Stage IIIC Cuta...
Stage IIIC Uvea...
Stage IV Acral ...
Stage IV Cutane...
Stage IV Uveal ...
Ipilimumab
Laboratory Biom...
Nivolumab
Relatlimab
Therapeutic Con...
18 Years - M.D. Anderson Cancer Center
Evaluation of the Impact of Adjuvants Accompanying Peptide Immunization in High-Risk MelanomaNCT00273910
High-Risk Melan...
gp100:209-217 (...
Montanide ISA-5...
Imiquimod
7 Years - National Institutes of Health Clinical Center (CC)
Minimal SN Tumor BurdenNCT01942603
Cutaneous Melan...
18 Years - European Organisation for Research and Treatment of Cancer - EORTC
A Study of SGN-CD228A in Advanced Solid TumorsNCT04042480
Cutaneous Melan...
Pleural Mesothe...
HER2 Negative B...
Non-small Cell ...
Colorectal Canc...
Pancreatic Duct...
SGN-CD228A
18 Years - Seagen Inc.
The MELAcare Study: A New Method for Surveillance of Melanoma PatientsNCT05253872
Cutaneous Melan...
The MelaCare in...
18 Years - Herlev and Gentofte Hospital
Quality of Life, Lifestyle, and Psychosocial Factors in Patients With MelanomaNCT04778449
Cutaneous Melan...
Medical Chart R...
Questionnaire A...
18 Years - M.D. Anderson Cancer Center
Neoadjuvant Combination Immunotherapy for Stage III MelanomaNCT03842943
Cutaneous Melan...
Pembrolizumab
Talimogene Lahe...
18 Years - University of Louisville
Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive MelanomaNCT01763164
Metastatic or U...
MEK162
Dacarbazine
18 Years - Pfizer
Minimal SN Tumor BurdenNCT01942603
Cutaneous Melan...
18 Years - European Organisation for Research and Treatment of Cancer - EORTC
Location of Lower Limb Cutaneous Melanomas as a Prognostic Factor.NCT04625491
Cutaneous Melan...
Anatomical Path...
Observational
- Hospital Universitario Virgen de la Arrixaca
Confirmatory Trial in the Evaluation of Ca Electroporation for the Treatment of Cutaneous MetastasesNCT03628417
Cutaneous Melan...
Calcium Electro...
Bleomycin based...
18 Years - 100 YearsSzeged University
IMCgp100-401 Rollover StudyNCT02889861
Malignant Melan...
IMCgp100
18 Years - Immunocore Ltd
Neoadjuvant and Adjuvant Checkpoint BlockadeNCT02519322
Cutaneous Melan...
Mucosal Melanom...
Ocular Melanoma
Stage III Acral...
Stage IIIB Cuta...
Stage IIIB Uvea...
Stage IIIC Cuta...
Stage IIIC Uvea...
Stage IV Acral ...
Stage IV Cutane...
Stage IV Uveal ...
Ipilimumab
Laboratory Biom...
Nivolumab
Relatlimab
Therapeutic Con...
18 Years - M.D. Anderson Cancer Center
TH1902 in Patients With Advanced Solid TumorsNCT04706962
Solid Tumor
TNBC - Triple-N...
Hormone Recepto...
Epithelial Ovar...
Endometrial Can...
Cutaneous Melan...
Thyroid Cancer
Small-cell Lung...
Prostate Cancer
SORT1+ Cancers
TH1902
18 Years - Theratechnologies
Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted VaccineNCT03633110
Cutaneous Melan...
Non-small Cell ...
Squamous Cell C...
Urothelial Carc...
Renal Cell Carc...
GEN-009 Adjuvan...
Nivolumab
Pembrolizumab
18 Years - Genocea Biosciences, Inc.
Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous MelanomaNCT01693068
N-Ras Mutated L...
Pimasertib
Dacarbazine
18 Years - EMD Serono
Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2NCT05482074
Recurrent Metas...
Cutaneous Melan...
Mucosal Melanom...
Uveal Melanoma
Olaparib
18 Years - Dana-Farber Cancer Institute
Phase II Study of Abraxane Plus Ipilimumab in Patients With Metastatic MelanomaNCT01827111
Melanoma
ABI-007
Ipilimumab
Phone Call
12 Years - 70 YearsM.D. Anderson Cancer Center
Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With MelanomaNCT02447939
Melanoma
Dabrafenib
Trametinib
18 Years - GlaxoSmithKline
Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk MelanomaNCT06319196
Cutaneous Melan...
Melanoma Stage ...
Mucosal Melanom...
Opdualag
Nivolumab
18 Years - University Health Network, Toronto
Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to LiverNCT01728051
Metastatic Live...
Ocular Melanoma
Cutaneous Melan...
Melphalan
Percutaneous He...
18 Years - Delcath Systems Inc.
Exercise to Boost Response to Checkpoint Blockade ImmunotherapyNCT05358938
Cutaneous Melan...
Cutaneous Squam...
Merkel Cell Car...
Exercise
Checkpoint Bloc...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
RTX-224 Monotherapy in Patients With Solid TumorsNCT05219578
Non Small Cell ...
Cutaneous Melan...
Head and Neck S...
Urothelial Carc...
TNBC - Triple-N...
RTX-224
18 Years - Rubius Therapeutics
Enhancing Skin Cancer Early Detection and Treatment in Primary CareNCT05675709
Cutaneous Melan...
Training and Ed...
18 Years - OHSU Knight Cancer Institute
Quality of Life, Lifestyle, and Psychosocial Factors in Patients With MelanomaNCT04778449
Cutaneous Melan...
Medical Chart R...
Questionnaire A...
18 Years - M.D. Anderson Cancer Center
Neoadjuvant Combination Immunotherapy for Stage III MelanomaNCT03842943
Cutaneous Melan...
Pembrolizumab
Talimogene Lahe...
18 Years - University of Louisville
Observational Basket Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic PlatformNCT05520099
Colorectal Canc...
Head and Neck S...
Non Small Cell ...
Cutaneous Melan...
Endometrial Can...
Urothelial Carc...
Clear Cell Rena...
Core Needle or ...
18 Years - Elephas
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy EvaluationNCT05059444
Bladder Carcino...
Ureter Carcinom...
Renal Pelvis Ca...
Non-small Cell ...
Invasive Breast...
Cutaneous Melan...
Esophageal Carc...
Gastroesophagea...
Gastric Adenoca...
Pancreatic Aden...
Squamous Cell C...
Epithelial Ovar...
Fallopian Tube ...
Endometrial Car...
Renal Cell Carc...
Guardant Reveal
18 Years - Guardant Health, Inc.
A Study To See Why Patients Agree To or Decline To Have Treatment After SurgeryNCT03843593
Cutaneous Melan...
Demographics Qu...
Adjuvant Treatm...
Functional Asse...
Functional Asse...
Decisional Regr...
Clinician Prefe...
18 Years - Memorial Sloan Kettering Cancer Center
Neoadjuvant and Adjuvant Checkpoint BlockadeNCT02519322
Cutaneous Melan...
Mucosal Melanom...
Ocular Melanoma
Stage III Acral...
Stage IIIB Cuta...
Stage IIIB Uvea...
Stage IIIC Cuta...
Stage IIIC Uvea...
Stage IV Acral ...
Stage IV Cutane...
Stage IV Uveal ...
Ipilimumab
Laboratory Biom...
Nivolumab
Relatlimab
Therapeutic Con...
18 Years - M.D. Anderson Cancer Center
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC FusionsNCT03947385
Metastatic Uvea...
Cutaneous Melan...
Colorectal Canc...
Other Solid Tum...
IDE196
Binimetinib
Crizotinib
18 Years - IDEAYA Biosciences
Exercise to Boost Response to Checkpoint Blockade ImmunotherapyNCT06008977
Cutaneous Melan...
Cutaneous Squam...
Merkel Cell Car...
Exercise Test
18 Years - AdventHealth Translational Research Institute
Expanded Access Program of Lifileucel (LN-144) in Patients With Unresectable or Metastatic MelanomaNCT05398640
Unresectable Me...
Metastatic Mela...
Lifileucel
18 Years - Iovance Biotherapeutics, Inc.
A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid TumorsNCT05576077
Breast Cancer
Colorectal Canc...
Uveal Melanoma
Cutaneous Melan...
Non-Small Cell ...
Head and Neck S...
TBio-4101
Pembrolizumab
18 Years - 70 YearsTurnstone Biologics, Corp.
Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to LiverNCT01728051
Metastatic Live...
Ocular Melanoma
Cutaneous Melan...
Melphalan
Percutaneous He...
18 Years - Delcath Systems Inc.
Study of RP1 Monotherapy and RP1 in Combination With NivolumabNCT03767348
Cancer
Melanoma (Skin)
Mismatch Repair...
Microsatellite ...
Non-melanoma Sk...
Cutaneous Melan...
NSCLC
RP1
nivolumab
18 Years - Replimune Inc.
A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced CancersNCT05544929
Carcinoma, Non-...
Cutaneous Melan...
Carcinoma, Rena...
Carcinoma, Ovar...
Nasopharyngeal ...
Carcinoma, Thym...
Anal Cancer
Mesothelioma
Esophagogastric...
High Microsatel...
Squamous Cell C...
Triple Negative...
KFA115
pembrolizumab
18 Years - Novartis
Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With MelanomaNCT02447939
Melanoma
Dabrafenib
Trametinib
18 Years - GlaxoSmithKline
A Study of GV20-0251 in Patients With Solid Tumor MalignanciesNCT05669430
Solid Tumor, Ad...
Refractory Canc...
Bladder Urothel...
Cholangiocarcin...
Adenocarcinoma ...
Endometrial Car...
Head and Neck C...
Cutaneous Melan...
Non-small Cell ...
Adenocarcinoma ...
GV20-0251
GV20-0251
18 Years - GV20 Therapeutics
Phase II Study of KW2871 Combined With High Dose Interferon-α2b in Patients With Metastatic MelanomaNCT00679289
Metastatic Mela...
Cutaneous Melan...
HDI
KW2871
KW2871
KW2871
18 Years - Ludwig Institute for Cancer Research
A Study of SGN-CD228A in Advanced Solid TumorsNCT04042480
Cutaneous Melan...
Pleural Mesothe...
HER2 Negative B...
Non-small Cell ...
Colorectal Canc...
Pancreatic Duct...
SGN-CD228A
18 Years - Seagen Inc.
Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced CancerNCT04121676
Advanced Cancer
AGEN2373
Botensilimab
18 Years - Agenus Inc.
GSK3359609 Plus Tremelimumab for the Treatment of Advanced Solid TumorsNCT03693612
Neoplasms
feladilimab
Tremelimumab
Docetaxel
Paclitaxel
Cetuximab
18 Years - GlaxoSmithKline
TH1902 in Patients With Advanced Solid TumorsNCT04706962
Solid Tumor
TNBC - Triple-N...
Hormone Recepto...
Epithelial Ovar...
Endometrial Can...
Cutaneous Melan...
Thyroid Cancer
Small-cell Lung...
Prostate Cancer
SORT1+ Cancers
TH1902
18 Years - Theratechnologies
5-year Study to Track Clinical Application of DecisionDx-Melanoma Gene Expression Profile Assay ResultsNCT02355574
Cutaneous Melan...
16 Years - Castle Biosciences Incorporated
Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory MelanomaNCT05628883
Metastatic Mela...
Unresectable Me...
Acral Melanoma
Mucosal Melanom...
Cutaneous Melan...
Ocular Melanoma
Uveal Melanoma
Iris Melanoma
Conjunctival Me...
Non-Cutaneous M...
TBio-4101
Cyclophosphamid...
Fludarabine
Interleukin-2
18 Years - 75 YearsH. Lee Moffitt Cancer Center and Research Institute
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin CancersNCT06223659
Cutaneous Melan...
Merkel Cell Car...
Skin Squamous C...
Eutectic Mixtur...
Placebo Adminis...
Questionnaire A...
18 Years - 99 YearsOhio State University Comprehensive Cancer Center
Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney CancerNCT00328861
Metastatic Mela...
Metastatic Kidn...
Natural Killer ...
IL-2
Cyclophosphamid...
Fludarabine
18 Years - National Institutes of Health Clinical Center (CC)
Expanded Access Program of Lifileucel (LN-144) in Patients With Unresectable or Metastatic MelanomaNCT05398640
Unresectable Me...
Metastatic Mela...
Lifileucel
18 Years - Iovance Biotherapeutics, Inc.
Exercise to Boost Response to Checkpoint Blockade ImmunotherapyNCT05358938
Cutaneous Melan...
Cutaneous Squam...
Merkel Cell Car...
Exercise
Checkpoint Bloc...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Sonazoid-Enhanced Ultrasound in Detecting Sentinel Lymph Node in Patients With Cutaneous MelanomaNCT02968680
Cutaneous Melan...
Melanoma
Sentinel Lymph ...
Ultrasonography
Sonazoid
19 Years - University of Southern California
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