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Spots Global Cancer Trial Database for Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis

Official Title: Prevention of Progression of Duodenal Adenomas to Cancer in Patients With Familial Adenomatous Polyposis (FAP)

Study ID: NCT00808743

Study Description

Brief Summary: Duodenal carcinomas are the leading cause of mortality in patients with Familial Adenomatous Polyposis (FAP) who underwent prophylactic colorectal surgery. The purpose of this study is to determine wether celecoxib combined with ursodeoxycholic acid is an effective chemoprevention strategy to influence the progression of duodenal adenomas to carcinomas in patients with FAP.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Academic Medical Center, Amsterdam, , Netherlands

University Medical Center, Groningen, , Netherlands

Leiden University Medical Center, Leiden, , Netherlands

University Medical Center St. Radboud, Nijmegen, , Netherlands

Erasmus Medical Center, Rotterdam, , Netherlands

Contact Details

Name: Fokko M Nagengast, MD, Ph D

Affiliation: University Medical Center St. Radboud Nijmegen, The Netherlands

Role: PRINCIPAL_INVESTIGATOR

Name: Bjorn WH van Heumen, MD

Affiliation: University Medical Center St. Radboud Nijmegen, The Netherlands

Role: PRINCIPAL_INVESTIGATOR

Name: Wilbert HM Peters, Ph D

Affiliation: University Medical Center St Radboud Nijmegen, The Netherlands

Role: PRINCIPAL_INVESTIGATOR

Name: Ellen Kampman, Ph D

Affiliation: University Medical Center St Radboud Nijmegen, The Netherlands

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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