Spots Global Cancer Trial Database for familial adenomatous polyposis
Every month we try and update this database with for familial adenomatous polyposis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy | NCT04678011 | Familial Adenom... | Personalized su... | 18 Years - | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis | NCT00808743 | Familial Adenom... Duodenal Neopla... Duodenal Polyps | Celecoxib Ursodeoxycholic... Placebo | 18 Years - 70 Years | Radboud University Medical Center | |
| Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis | NCT04695964 | Ulcerative Coli... Colorectal Canc... Crohn Disease Familial Adenom... Ulcerative Coli... Ulcerative Coli... Crohn Colitis Ileal Pouch | ICG-NIRF Imagin... | 18 Years - | Charite University, Berlin, Germany | |
| Incidental Cancer in Familial Adenomatous Polyposis | NCT05171426 | Cancer | - | Dr. Ersin Arslan Education and Training Hospital | ||
| Testing ONC201 to Prevent Colorectal Cancer | NCT05630794 | Colorectal Aden... Colorectal Carc... Familial Adenom... Multiple Adenom... | Biopsy Biospecimen Col... Colonoscopy Dordaviprone Questionnaire A... Sigmoidoscopy | 18 Years - | National Cancer Institute (NCI) | |
| Trial of eRapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance | NCT04230499 | Familial Adenom... | Encapsulated Ra... | 18 Years - | Rapamycin Holdings Inc. | |
| CryoBalloon Ablation for Treatment of Duodenal Adenomas | NCT03847636 | Duodenal Adenom... Familial Adenom... | CryoBalloon abl... | 18 Years - | Johns Hopkins University | |
| A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients | NCT01187901 | Adenomatous Pol... | Erlotinib Sulindac Placebo A Placebo B | 18 Years - 69 Years | University of Utah | |
| Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer | NCT00675636 | Colorectal Canc... Hereditary Non-... Precancerous Co... | study of socioe... evaluation of c... study of high r... | - 100 Years | Vanderbilt University Medical Center | |
| Colorectal Adenoma Canceration in FAP | NCT04531930 | Familial Adenom... | surgery enhanced colono... self choosed me... | 18 Years - 40 Years | Changhai Hospital | |
| A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis | NCT04677998 | Familial Adenom... | Personalized su... | 18 Years - | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| Incidental Cancer in Familial Adenomatous Polyposis | NCT05171426 | Cancer | - | Dr. Ersin Arslan Education and Training Hospital | ||
| Endomicrocancer: Confocal Endomicroscopy in Patients With High Risk of Colorectal Cancer | NCT01052376 | Inflammatory Bo... Familial Adenom... | Confocal endomi... | 18 Years - 75 Years | Nantes University Hospital | |
| Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis | NCT04695184 | Ulcerative Coli... Colorectal Canc... Crohn Disease Familial Adenom... Crohn Colitis Ileal Pouch | ICG-NIRF Imagin... | 18 Years - | Charite University, Berlin, Germany | |
| Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP) | NCT02656134 | Familial Adenom... | Duodenoscopy an... Molecular analy... | 15 Years - 65 Years | University of Sao Paulo | |
| Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses | NCT04709445 | Bowel Obstructi... Bowel Ischemia Diverticulitis Abnormality of ... Symptomatic Dis... Stoma Ileostomy Cancer of the G... Crohn Disease Ulcerative Coli... Familial Adenom... Pancreatic Neop... Hepatobiliary N... | ICG-NIRF Imagin... | 18 Years - | Charite University, Berlin, Germany | |
| A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients | NCT01187901 | Adenomatous Pol... | Erlotinib Sulindac Placebo A Placebo B | 18 Years - 69 Years | University of Utah | |
| Ileal Pouch-Anal Anastomosis Registry | NCT01026480 | Ileal Pouch-Ana... | - | Boston Medical Center | ||
| DNA Adductomics for Colorectal Cancer Investigation | NCT04865601 | Colorectal Canc... Familial Adenom... Hereditary Non-... Lynch Syndrome | resectomy of th... | 18 Years - | University of Copenhagen | |
| Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease | NCT01656746 | Adenomatous Pol... Crohn Disease Familial Adenom... Hereditary Inte... Recurrent Colon... Stage I Colon C... Stage IIA Colon... Stage IIB Colon... Stage IIC Colon... Stage IIIA Colo... Stage IIIB Colo... Stage IIIC Colo... | therapeutic lap... | 18 Years - 80 Years | Ohio State University Comprehensive Cancer Center | |
| Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis | NCT00033371 | Colorectal Canc... Familial Adenom... | Celecoxib Placebo eflornithine Laboratory biom... Questionnaire a... | 18 Years - 65 Years | National Cancer Institute (NCI) | |
| Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP) | NCT00927485 | Familial Adenom... | Calcumin (Curcu... Risk Factor Que... Blood samples Biopsies (Sigmo... Biopsies (Upper... | 21 Years - 85 Years | University of Puerto Rico | |
| Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis. | NCT03061591 | Familial Adenom... FAP FAP Gene Mutati... | Wholistic Turme... Placebo | 18 Years - 70 Years | Tel-Aviv Sourasky Medical Center | |
| Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients | NCT00248053 | Familial Adenom... | curcumin | 18 Years - 85 Years | Johns Hopkins University | |
| Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis | NCT00808743 | Familial Adenom... Duodenal Neopla... Duodenal Polyps | Celecoxib Ursodeoxycholic... Placebo | 18 Years - 70 Years | Radboud University Medical Center | |
| Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes | NCT02198092 | Familial Adenom... Map Syndrome Lynch Syndrome Hnpcc Colorectal Canc... | Epi proColon Te... | 18 Years - | University of Pennsylvania | |
| MUTYH-associated Polyposis | NCT03847532 | MutYH-associate... | Sanger sequenci... | 18 Years - 71 Years | State Scientific Centre of Coloproctology, Russian Federation | |
| Colorectal Adenoma Canceration in FAP | NCT04531930 | Familial Adenom... | surgery enhanced colono... self choosed me... | 18 Years - 40 Years | Changhai Hospital | |
| The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis | NCT05402891 | Familial Adenom... | Lithium Carbona... | 18 Years - 35 Years | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| Molecular Fluorescence Endoscopy in Patients With Familial Adenomatous Polyposis, Using Bevacizumab-IRDye800CW | NCT02113202 | Adenomatous Pol... | Bevacizumab-IRD... Near infrared f... | 18 Years - 70 Years | University Medical Center Groningen | |
| Endoscopic Papillectomy for Ampullary Adenomas | NCT03494543 | Ampullary Adeno... Familial Adenom... | Endoscopic Papi... | 18 Years - | Arcispedale Santa Maria Nuova-IRCCS | |
| A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients | NCT01187901 | Adenomatous Pol... | Erlotinib Sulindac Placebo A Placebo B | 18 Years - 69 Years | University of Utah | |
| Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP) | NCT00770991 | Familial Adenom... | Black raspberry... Black Raspberry... Black Raspberry... | 18 Years - | The Cleveland Clinic | |
| Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses | NCT00663819 | Rectal Cancer Ulcerative Coli... Familial Adenom... Diverticulitis | GORE SEAMGUARD®... Staple line wit... | 18 Years - | W.L.Gore & Associates | |
| Niclosamide for Familial Adenomatous Polyposis | NCT04296851 | Familial Adenom... | Niclosamide placebo | 20 Years - 65 Years | Yonsei University | |
| Preventive Anti-inflammatory Diet to Reduce Gastro-intestinal Inflammation in FAP Patients: a Prospective Pilot Study | NCT04552405 | Familial Adenom... | Anti-inflammato... | 18 Years - | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| Azithromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis | NCT04454151 | Familial Adenom... | Azithromycin Ta... | 18 Years - 120 Years | Tel-Aviv Sourasky Medical Center | |
| Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP) | NCT01483144 | Familial Adenom... | Eflornithine Eflornithine Pl... Sulindac 150 MG Sulindac placeb... | 18 Years - | Cancer Prevention Pharmaceuticals, Inc. | |
| Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis | NCT03806426 | Familial Adenom... | Eicosapentaenoi... Placebo | 18 Years - 65 Years | S.L.A. Pharma AG | |
| The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study | NCT01725490 | Familial Adenom... | Metformin Metformin Placebo | 20 Years - 65 Years | Yonsei University | |
| Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer | NCT00675636 | Colorectal Canc... Hereditary Non-... Precancerous Co... | study of socioe... evaluation of c... study of high r... | - 100 Years | Vanderbilt University Medical Center | |
| Testing Obeticholic Acid for Familial Adenomatous Polyposis | NCT05223036 | Attenuated Fami... Colorectal Carc... Duodenal Carcin... Familial Adenom... | Biopsy Biospecimen Col... Gastrointestina... Obeticholic Aci... Placebo Adminis... Questionnaire A... | 18 Years - | National Cancer Institute (NCI) | |
| CryoBalloon Ablation for Treatment of Duodenal Adenomas | NCT03847636 | Duodenal Adenom... Familial Adenom... | CryoBalloon abl... | 18 Years - | Johns Hopkins University | |
| Ileal Pouch-Anal Anastomosis Registry | NCT01026480 | Ileal Pouch-Ana... | - | Boston Medical Center | ||
| Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP) | NCT01483144 | Familial Adenom... | Eflornithine Eflornithine Pl... Sulindac 150 MG Sulindac placeb... | 18 Years - | Cancer Prevention Pharmaceuticals, Inc. | |
| Preventive Anti-inflammatory Diet to Reduce Gastro-intestinal Inflammation in FAP Patients: a Prospective Pilot Study | NCT04552405 | Familial Adenom... | Anti-inflammato... | 18 Years - | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| Inherited Cancer Early Diagnosis (ICED) Study | NCT06163365 | Li Fraumeni Syn... Lynch Syndrome Hereditary Diff... Cowden Syndrome Peutz-Jeghers S... Familial Adenom... SMAD4 Gene Muta... MutYH-associate... | 18 Years - | Royal Marsden NHS Foundation Trust | ||
| Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers | NCT00503035 | Familial Adenom... | Celecoxib Colonoscopy Bio... | 16 Years - | M.D. Anderson Cancer Center | |
| Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis | NCT06308445 | Familial Adenom... | Rapamycin | 12 Years - 17 Years | University Hospital, Toulouse | |
| DNA Adductomics for Colorectal Cancer Investigation | NCT04865601 | Colorectal Canc... Familial Adenom... Hereditary Non-... Lynch Syndrome | resectomy of th... | 18 Years - | University of Copenhagen | |
| Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis | NCT00033371 | Colorectal Canc... Familial Adenom... | Celecoxib Placebo eflornithine Laboratory biom... Questionnaire a... | 18 Years - 65 Years | National Cancer Institute (NCI) | |
| Testing Obeticholic Acid for Familial Adenomatous Polyposis | NCT05223036 | Attenuated Fami... Colorectal Carc... Duodenal Carcin... Familial Adenom... | Biopsy Biospecimen Col... Gastrointestina... Obeticholic Aci... Placebo Adminis... Questionnaire A... | 18 Years - | National Cancer Institute (NCI) | |
| Visualization of the Papilla Through Use of the NuView Device in Patients With FAP | NCT05657145 | Familial Adenom... | 18 Years - 70 Years | Vanderbilt University Medical Center | ||
| Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis | NCT00685568 | Colorectal Canc... Precancerous Co... | celecoxib placebo | 10 Years - 14 Years | M.D. Anderson Cancer Center | |
| Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01 | NCT04674228 | Familial Adenom... | Electronic Heal... | - | National Cancer Institute (NCI) | |
| Endoscopic Papillectomy for Ampullary Adenomas | NCT03494543 | Ampullary Adeno... Familial Adenom... | Endoscopic Papi... | 18 Years - | Arcispedale Santa Maria Nuova-IRCCS | |
| Integrated Cancer Repository for Cancer Research | NCT02012699 | Pancreatic Canc... Thyroid Cancer Lung Cancer Esophageal Canc... Thymus Cancer Colon Cancer Rectal Cancer Gastrointestina... Anal Cancer Bile Duct Cance... Duodenal Cancer Gallbladder Can... Gastric Cancer Liver Cancer Small Intestine... Peritoneal Surf... Familial Adenom... Lynch Syndrome Bladder Cancer Kidney Cancer Penile Cancer Prostate Cancer Testicular Canc... Ureter Cancer Urethral Cancer Hypopharyngeal ... Laryngeal Cance... Lip Cancer Oral Cavity Can... Nasopharyngeal ... Oropharyngeal C... Paranasal Sinus... Nasal Cavity Ca... Salivary Gland ... Skin Cancer Central Nervous... Central Nervous... Mesothelioma Breast Cancer Leukemia Melanoma Sarcoma Unknown Primary... Multiple Myelom... Ovarian Cancer Endometrial Can... Vaginal Cancer Neuroendocrine ... Plasma Cell Dys... Healthy Control | 19 Years - 110 Years | University of Nebraska | ||
| Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients | NCT00151476 | Familial Adenom... | Celecoxib Routine Medical... | 12 Years - | Pfizer | |
| Curcumin in Treating Patients With Familial Adenomatous Polyposis | NCT00641147 | Familial Adenom... | Curcumin Laboratory Biom... Placebo | 18 Years - 85 Years | National Cancer Institute (NCI) |
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