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Brief Title: Dragon III-Phase 3: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer
Official Title: Efficacy Study of FLOT Versus SOX Regimen as Neoadjuvant Chemotherapy for Patients With Locally Advanced Gastric Cancer: A Phase 3 Multi-center Randomized Controlled Trial
Study ID: NCT04384601
Brief Summary: DRAGON III research, Neoadjuvant Chemotherapy (FLOT versus SOX) for Gastric Cancer, is an investigator initiated; phase 3, open label, multi-center randomized controlled study.
Detailed Description: Non inferiority of SOX will be tested against FLOT. This study will be conducted at multiple center of China and will invite international centers to join it.The sponsor of this study is Ruijin Hospital and the project is supported by the Shanghai Key Laboratory of Gastric Neoplasms and Institute of Digestive Surgery, Shanghai.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, China
Name: Birendra K Sah, PH D
Affiliation: Ruijin Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Chen Li, PH D
Affiliation: Ruijin Hospital
Role: STUDY_DIRECTOR
Name: Zhenggang Zhu, PH D
Affiliation: Ruijin Hospital
Role: STUDY_CHAIR