Spots Global Cancer Trial Database for Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy
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Trial Identification
Brief Title: Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy
Official Title: Effects of Gut Microflora on the Immune and Nutritional Status of CRC Patients After Chemotherapy
Study ID: NCT02169388
Study Description
Brief Summary: Probiotics modulate the gut microflora and immune status in CRC,which can reduce the side effects of chemotherapy such as diarrhea,infection,neutropenia etc.
Detailed Description: Chemotherapy destroys the intestinal mucosal barrier, affects intestinal flora, causing bacterial translocation, infection and other complications; Probiotics may restore the intestinal immunity, mucosal barrier, and nutrient absorption.The adverse effects of chemotherapy and the malnutrition status may be relieved via probiotic administration.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Gastroenterology,Qilu Hospital,Shandong University, Jinan, Shandong, China
Contact Details
Name: Yanqing Li, MD.PhD
Affiliation: Qilu Hospital, Shandong University
Role: PRINCIPAL_INVESTIGATOR
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