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Brief Title: Valproic Acid (Depakote ER) in Patients With Advanced Thyroid Cancer
Official Title: A Phase II Trial of Valproic Acid (Depakote ER ®) in Patients With Advanced Thyroid Cancers of Follicular Origin, Who Are Thyroglobulin Positive/RAI Unresponsive
Study ID: NCT00525135
Brief Summary: RATIONALE: Drugs such as valproic acid may make thyroid cancers more radioiodine sensitive, which will allow for detection of tumor and make further ablation treatment effective.
Detailed Description: PURPOSE: This phase II trial is studying how well valproic acid works in treating patients with thyroid cancers that do not respond well to other treatments.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UCSF Comprehensive Cancer Center, San Francisco, California, United States
Name: Electron Kebebew, MD
Affiliation: University of California, San Francisco
Role: PRINCIPAL_INVESTIGATOR