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Spots Global Cancer Trial Database for The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy

Official Title: Pilot Studies Testing the Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy

Study ID: NCT05688904

Interventions

Imipramine
Vehicle

Study Description

Brief Summary: The purpose of this study is testing the use of topical Imipramine in combination with topical photodynamic therapy's (PDT) effect on pain following treatment. PDT is a commonly used treatment in dermatology for patients who have many pre-cancers (actinic keratosis-AKs) on their skin. These are both FDA-approved treatments, but this study is evaluating their use in combination, which has not been evaluated in the past. The investigators have been doing studies using animals that suggest that imipramine might make the PDT less painful and might help it work better. In order to participate, the subject and their dermatologist have decided that they would benefit from PDT to treat their skin due to many AK precancerous lesions. Please note that neither PDT nor imipramine are experimental treatments, but treating their skin with imipramine before PDT is a new approach.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Wright State Physicians, Fairborn, Ohio, United States

Contact Details

Name: Craig Rohan, MD

Affiliation: Wright State University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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