Spots Global Cancer Trial Database for actinic keratosis
Every month we try and update this database with for actinic keratosis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up | NCT02547363 | Actinic Keratos... | LEO 43204 gel Vehicle gel | 18 Years - | LEO Pharma | |
| The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy | NCT05688904 | Imipramine Photodynamic Th... Actinic Keratos... | Imipramine Vehicle | 18 Years - | Wright State University | |
| Study of SOR007 Ointment for Actinic Keratosis | NCT03083470 | Actinic Keratos... | SOR007 (Uncoate... SOR007 Ointment... | 45 Years - 85 Years | DFB Soria, LLC | |
| Efficacy and Safety Phase II Study of SR-T100 to Treat Actinic Keratosis | NCT01516515 | Actinic Keratos... | Vehicle gel SR-T100 with 2.... | 18 Years - | G&E Herbal Biotechnology Co., LTD | |
| Patient Decision Aid for the Treatment of Actinic Keratosis | NCT06008171 | Actinic Keratos... Patient Decisio... | Patient Decisio... | 18 Years - | Maastricht University Medical Center | |
| Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp | NCT05662202 | Actinic Keratos... | BF-200 ALA and ... Vehicle and red... | 18 Years - | Biofrontera Bioscience GmbH | |
| Photodynamic Therapy in Treating Patients With Skin Cancer | NCT00002975 | Non-melanomatou... Precancerous Co... | aminolevulinic ... | - | Roswell Park Cancer Institute | |
| A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp) | NCT00700063 | Actinic Keratos... | PEP005 Topical ... PEP005 Topical ... PEP005 Topical ... Vehicle gel PEP005 Topical ... PEP005 Topical ... PEP005 Topical ... Vehicle gel | 18 Years - | Peplin | |
| High- and Low-risk Actinic Keratosis Referrals to Secondary Care | NCT05976061 | Actinic Keratos... | 18 Years - | Maastricht University Medical Center | ||
| Levulan PDT Versus Vehicle for Extremity Actinic Keratoses (AK) | NCT01458587 | Keratosis, Acti... | Aminolevulinic ... Vehicle PDT (VE... | 18 Years - | DUSA Pharmaceuticals, Inc. | |
| Study on the Efficacy of LAS41005 in the Treatment of Actinic Keratosis | NCT00987246 | Actinic Keratos... | Placebo Gel LAS41005 LAS106521 | 18 Years - 85 Years | Almirall, S.A. | |
| MRB 0.3% Serum Effectiveness on 2 Early Clinical Markers of Photoinduced Cutaneous Aging: Actinic Lentigo and Actinic Keratosis | NCT05152407 | Actinic Keratos... Actinic Lentigo | Topical applica... | 40 Years - | NAOS Institute of Life Science | |
| A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) | NCT00915551 | Actinic Keratos... | PEP005 (Ingenol... Vehicle Gel | 18 Years - | Peplin | |
| Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis | NCT02120456 | Actinic Keratos... | LEO 43204 Placebo | 18 Years - | LEO Pharma | |
| A Study of Equivalence of Generic Ingenol Mebutate Gel 0.05% and Picato Gel 0.05% in Subjects With Actinic Keratosis | NCT02654769 | Actinic Keratos... | Ingenol Mebutat... Generic Ingenol... Vehicle Foam | 18 Years - 95 Years | Actavis Inc. | |
| A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand | NCT00544297 | Actinic Keratos... | PEP005 gel | 18 Years - | Peplin | |
| Biomarker Database Registry for Photodynamic Therapy | NCT03319251 | Actinic Keratos... | 18 Years - | The Cleveland Clinic | ||
| To Compare Safety and Efficacy of Perrigo's Drug Product Compared to an FDA Approved Drug Product in the Treatment of Actinic Keratosis | NCT02385318 | Actinic Keratos... | Ingenol Mebutat... Ingenol Mebutat... Placebo gel | 18 Years - | Padagis LLC | |
| Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic Keratoses | NCT00107965 | Actinic Keratos... | PEP005 PEP005 PEP005 PEP005 PEP005 PEP005 PEP005 PEP005 | 18 Years - | Peplin | |
| Imiquimod and Actinic Keratoses: an Observational Study | NCT01151956 | Actinic Keratos... | - | Federal University Teaching Hospital, Feldkirch, Austria | ||
| A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies | NCT00953732 | Actinic Keratos... | Lesion count | 18 Years - | Peplin | |
| Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up | NCT02549339 | Actinic Keratos... | LEO 43204 gel Vehicle gel | 18 Years - | LEO Pharma | |
| Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the Forearm | NCT01803477 | Actinic Keratos... | once daily for ... | 18 Years - | LEO Pharma | |
| Activity & Safety Study of KX2-391 Ointment in Participants With Actinic Keratosis on the Face or Scalp | NCT02838628 | Actinic Keratos... | 50 mg of KX2-39... 50 mg of KX2-39... | 18 Years - | Almirall, S.A. | |
| Pharmacokinetic Study to Evaluate the Extent of Systemic Absorption of PEP005 | NCT00544258 | Actinic Keratos... | PEP005 | 18 Years - | Peplin | |
| Safety and Effectiveness Study of Actinic Keratosis Treatment Following Cryosurgery | NCT00894647 | Actinic Keratos... | imiquimod cream placebo cream | 18 Years - | Graceway Pharmaceuticals, LLC | |
| An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis | NCT03200912 | ACTINIC KERATOS... | Ingenol Mebutat... Generic Ingenol... Vehicle Foam | 18 Years - 95 Years | Actavis Inc. | |
| Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT) | NCT01000636 | Actinic Keratos... | Metvix PDT | 18 Years - | Galderma R&D | |
| Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK) | NCT01475955 | Actinic Keratos... | Broad Area ALA ... Broad Area ALA ... broad area ALA ... Spot ALA 2 hour... Vehicle PDT Blue Light Trea... | 18 Years - | DUSA Pharmaceuticals, Inc. | |
| A Study of Tirbanibulin on the Wellbeing of Participants With Actinic Keratoses | NCT05741294 | Actinic Keratos... | Tirbanibulin 2.... | 18 Years - | Almirall, S.A. | |
| PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy Subjects | NCT01302925 | Healthy Actinic Keratos... | PEP005 Gel PEP005 Gel | 18 Years - | Peplin | |
| T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum | NCT00002811 | Precancerous Co... | liposomal T4N5 ... | 2 Years - 60 Years | National Cancer Institute (NCI) | |
| A Multi-Center Study to Evaluate the Efficacy and Safety of KX01 Ointment 1% on Actinic Keratosis on Face or Scalp | NCT05231044 | Actinic Keratos... | KX01 ointment 1... Placebo | 20 Years - | PharmaEssentia | |
| A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) | NCT00916006 | Actinic Keratos... | PEP005 Gel Vehicle gel | 18 Years - | Peplin | |
| Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis | NCT00116649 | Keratosis | imiquimod cream | 18 Years - | Graceway Pharmaceuticals, LLC | |
| Efficacy and Safety Study of LAS41007 in the Treatment of Actinic Keratosis | NCT00991861 | Actinic Keratos... | LAS41007 o.d. LAS41007 b.i.d. LAS106521 | 18 Years - | Almirall, S.A. | |
| Menthol for PDT Pain Relief | NCT02984072 | Actinic Keratos... | Menthol Aqueous Cream | 18 Years - 100 Years | University of Dundee | |
| Double-blind, Randomized, Vehicle- and Comparator-controlled, Multi-center Trial to Evaluate the Efficacy and Safety of LAS41007 in the Treatment of Actinic Keratosis | NCT01265602 | Actinic Keratos... | LAS41007 LASW1510 vehicle of LAS4... | 18 Years - | Almirall, S.A. | |
| Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients | NCT05699603 | Actinic Keratos... | Biopsy Calcipotriene Fluorouracil | 18 Years - | National Cancer Institute (NCI) | |
| Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis | NCT03210740 | Actinic Keratos... | AM001 Cream, 7.... Vehicle Cream | 18 Years - 80 Years | AmDerma | |
| 5fluorouracil for Advanced Photoaging | NCT01405144 | Photoaging Actinic Keratos... | 5-fluoruracil 5-fluoruracil | 50 Years - 75 Years | Federal University of São Paulo | |
| Tirbanibulin 1% Ointment for the Treatment of Chronically Sun-damaged Skin on the Face | NCT05900258 | Actinic Keratos... | Tirbanibulin | - | Medical University of Graz | |
| Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses | NCT02952898 | Actinic Keratos... | GDC 695 Diclofenac Sodi... Vehicle gel | 18 Years - | Balmoral Medical company | |
| PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy | NCT01449513 | Actinic Keratos... | Ingenol mebutat... Placebo Gel | 18 Years - | LEO Pharma | |
| Nanocytology Test to Evaluate Skin Cancer in High Risk Patients | NCT01905891 | Actinic Keratos... Squamous Cell C... | Superficial sha... | 18 Years - 89 Years | Northwestern University | |
| A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers | NCT00850811 | Actinic Keratos... | PEP005 (ingenol... | 18 Years - 65 Years | Peplin | |
| Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis | NCT02242747 | Actinic Keratos... | ingenol mebutat... 5% 5-FU | 18 Years - | University of Sao Paulo | |
| Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis | NCT02100813 | Actinic Keratos... | LEO 43204 Placebo | 18 Years - | LEO Pharma | |
| PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology | NCT01387711 | Actinic Keratos... | PEP005 (Ingenol... | 18 Years - | LEO Pharma | |
| Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil | NCT02938715 | Actinic Keratos... | teledermatology... | 18 Years - | University of California, Davis | |
| Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis | NCT00116649 | Keratosis | imiquimod cream | 18 Years - | Graceway Pharmaceuticals, LLC | |
| Evaluation of Efficacy and Safety of BF-200 ALA Used With Photodynamic Therapy in Patients With Actinic Keratosis. | NCT02799082 | Actinic Keratos... | Vehicle BF-200 ALA | 18 Years - 85 Years | Biofrontera Bioscience GmbH | |
| A Study to Evaluate the Effectiveness and Safety of Multiple Applications of Imiquimod 5% Cream for the Treatment of Actinic Keratoses in Organ Transplant Recipients | NCT00189267 | Actinic Keratos... | Imiquimod 5 % C... | 18 Years - | Viatris Inc. | |
| A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers | NCT00850681 | Actinic Keratos... | PEP005 (ingenol... | 18 Years - 65 Years | Peplin | |
| A Bioequivalence Study With Clinical Endpoints Comparing Generic Imiquimod Cream, 3.75% and Zyclara™ (Imiquimod) Cream, 3.75% in Subjects With Actinic Keratoses | NCT01502020 | Actinic Keratos... | imiquimod cream... Vehicle Cream imiquimod cream... | 18 Years - | Actavis Mid-Atlantic LLC | |
| Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up | NCT02547363 | Actinic Keratos... | LEO 43204 gel Vehicle gel | 18 Years - | LEO Pharma | |
| Ingenol Mebutate (Picato®) With Methyl Aminolevulinate Photodynamic Therapy for the Treatment of Actinic Keratosis | NCT02354391 | Actinic Keratos... | Ingenol mebutat... Ingenol mebutat... MAL PDT day 5 | 40 Years - | Pacific Dermaesthetics | |
| Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis | NCT02100813 | Actinic Keratos... | LEO 43204 Placebo | 18 Years - | LEO Pharma | |
| Oral Isotretinoin Versus Topical Tretinoin for Actinic Keratosis | NCT02278861 | Actinic Keratos... | Oral isotretino... Tretinoin 0,05%... Sunscreen FPS 6... | 50 Years - 75 Years | Universidade Federal de Goias | |
| Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States | NCT02867722 | Actinic Keratos... Non-melanoma Sk... | aminolevulinic ... | 18 Years - | Brigham and Women's Hospital | |
| Study to Determine the Safety of PEP005 0.025% and 0.05% Topical Gel in Patients With Actinic Keratoses | NCT00375739 | Actinic Keratos... | PEP005 | 18 Years - | Peplin | |
| Efficacy of AFL-assisted PDT With Short Incubation Time in Actinic Keratosis | NCT02248298 | Actinic Keratos... | 2h-AFL-PDT 3h-AFL-PDT 3hr-MAL-PDT | 18 Years - 87 Years | Dong-A University | |
| Celecoxib in Preventing Skin Cancer in Patients With Actinic Keratoses | NCT00027976 | Precancerous Co... | celecoxib Placebo | 18 Years - | University of Alabama at Birmingham | |
| A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations | NCT00742391 | Actinic Keratos... | PEP005 (ingenol... Vehicle gel | 18 Years - | Peplin | |
| Ingenol Mebutate 0.015% Gel in the Treatment of Actinic Keratoses (AK) on the Face and Scalp | NCT01836367 | Actinic Keratos... | Ingenol Mebutat... | 18 Years - | Icahn School of Medicine at Mount Sinai | |
| Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses | NCT00814528 | Actinic Keratos... | 5-ALA plus Blu-... 5-FU, Imiquimod... | 18 Years - 95 Years | University of Chicago | |
| Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses | NCT00814528 | Actinic Keratos... | 5-ALA plus Blu-... 5-FU, Imiquimod... | 18 Years - 95 Years | University of Chicago | |
| Indoor Daylight Photo Dynamic Therapy for Actinic Keratosis | NCT03805737 | Actinic Keratos... | Amulez and sunl... Amulez and red ... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Safety and Effectiveness Study of Imiquimod Creams for the Treatment of Actinic Keratoses (AKs) | NCT00603798 | Actinic Keratos... | Imiquimod cream Placebo cream Imiquimod cream | 18 Years - | Graceway Pharmaceuticals, LLC | |
| Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK) | NCT01475955 | Actinic Keratos... | Broad Area ALA ... Broad Area ALA ... broad area ALA ... Spot ALA 2 hour... Vehicle PDT Blue Light Trea... | 18 Years - | DUSA Pharmaceuticals, Inc. | |
| Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo | NCT02902822 | Erysipelas Impetigo Herpes Zoster Molluscum Conta... Warts Tinea Melanoma Actinic Keratos... Basal Cell Carc... Squamous Cell C... | Screening Tele-dermatolog... | 18 Years - 99 Years | Centro Studi Gised | |
| Daylight Photodynamic Therapy for Actinic Keratosis and Skin Field Cancerization | NCT03013647 | Actinic Keratos... | Methyl Aminolev... | - | University of Sao Paulo General Hospital | |
| Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis | NCT03210740 | Actinic Keratos... | AM001 Cream, 7.... Vehicle Cream | 18 Years - 80 Years | AmDerma | |
| Measuring Adherence To Topical 5-Fluorouracil in a Clinic Population | NCT00696488 | Actinic Keratos... | Fluorouracil 0.... | 50 Years - | Wake Forest University Health Sciences | |
| Safety, Tolerability, and Efficacy Study of LFX453 in Actinic Keratosis Patients | NCT02404389 | Actinic Keratos... | Investigational... Active comparat... | 18 Years - 75 Years | Novartis | |
| Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis | NCT03210740 | Actinic Keratos... | AM001 Cream, 7.... Vehicle Cream | 18 Years - 80 Years | AmDerma | |
| A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on Actinic Keratosis on Face or Scalp (AK004) | NCT03285490 | Actinic Keratos... | KX2-391 Ointmen... Placebo | 18 Years - | Almirall, S.A. | |
| Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities | NCT02137785 | Actinic Keratos... | Aminolevulinic ... Topical Solutio... Blue Light Phot... | 18 Years - | DUSA Pharmaceuticals, Inc. | |
| Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up | NCT02549339 | Actinic Keratos... | LEO 43204 gel Vehicle gel | 18 Years - | LEO Pharma | |
| Effect of IDEA-070 on Pain and Inflammation Induced by PDT | NCT00269074 | Actinic Keratos... | IDEA-070 | 18 Years - 85 Years | IDEA AG |
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