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Spots Global Cancer Trial Database for Neo-adjuvant Peptide Receptor Mediated Radiotherapy With 177Lutetium in Front of Curative Intended Liver Transplantation in Patients With Hepatic Metastasis of Neuroendocrine Tumors (NEO-LEBE)

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Trial Identification

Brief Title: Neo-adjuvant Peptide Receptor Mediated Radiotherapy With 177Lutetium in Front of Curative Intended Liver Transplantation in Patients With Hepatic Metastasis of Neuroendocrine Tumors (NEO-LEBE)

Official Title: Neo-adjuvant Peptide Receptor Mediated Radiotherapy With 177Lutetium in Front of Curative Intended Liver Transplantation in Patients With Hepatic Metastasis of Neuroendocrine Tumors

Study ID: NCT01201096

Study Description

Brief Summary: The purpose of this study is to show the tumor free long term survival of patients with isolated non-resectable liver metastases of neuroendocrine tumors after neo-adjuvant radio receptor treatment and following liver transplantation.

Detailed Description: Matching patient will be treated neo-adjuvant at the hospital with 177 Lutetium peptide receptor radiotherapy in two following courses. After this treatment it will follow the liver transplantation within 9 month as postmortal or living donor liver transplantation. Under certain conditions concerning the evaluation examinations patients can be included in the study. Most important factors are no evidence of disease outside the liver, removed primary tumor, patients between 18 and 60 years, no curative surgical resection of the liver metastasis possible.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Center for neuroendokrine tumors, Zentralklinik Bad Berka, Bad Berka, Thüringen, Germany

Department of general-, visceral- and vascular surgery, University of Jena, Jena, Thüringen, Germany

Contact Details

Name: Christine Wurst, Dr. med.

Affiliation: Department of general-, visceral- and vascular surgery, University of Jena

Role: PRINCIPAL_INVESTIGATOR

Name: Dieter Hörsch, Prof. Dr. med

Affiliation: Zentrum für neuroendokrine Tumore, Zentralklinik Bad Berka

Role: STUDY_DIRECTOR

Name: Utz Settmacher, Prof. Dr. med.

Affiliation: Department of general-, visceral- and vascular surgery, University of Jena

Role: STUDY_CHAIR

Name: R. B. Baum, Prof.Dr.med.

Affiliation: Center of neuroendocrine tumors, Zentralklinik Bad Berka

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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