Spots Global Cancer Trial Database for liver metastasis
Every month we try and update this database with for liver metastasis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer | NCT01762813 | Colorectal Canc... | open and laparo... | 18 Years - | Helse Stavanger HF | |
| Postoperative Folfox4 Only Versus Folfox4 Plus Transhepatic Arterial Chemotherapy (TAC) in the Treatment Unresectable Liver Metastasis of Colorectal Cancer | NCT00869271 | Unresectable Li... | tac + folfox4 Folfox4 | 18 Years - 75 Years | Fudan University | |
| Dynamic Contrast-enhanced MRI Combined With IVIM-DWI for Early Prediction of Chemosensitivity in Liver MBC | NCT05550090 | Metastatic Brea... | Chemotherapy | 18 Years - | Zhejiang Cancer Hospital | |
| Treatment Outcomes of Hepatic Metastasis After FOLFOX-4 Therapy | NCT00610636 | Colorectal Canc... | Hepatic resecti... | 18 Years - 80 Years | National Taiwan University Hospital | |
| Feasibility Study of Neoadjuvant Chemotherapy Modified FOLFOX6 for Resectable Liver Metastases of Colorectal Cancers | NCT00594529 | Colorectal Canc... Liver Metastasi... | Surgery | 20 Years - 80 Years | Kyoto University Hospital | |
| Transhepatic Arterial Chemotherapy (TAC) Versus Transcatheter Arterial Chemoembolization (TACE) Plus Folfox4 as the Treatment of Unresectable Liver Metastasis of Colorectal Cancer | NCT00868569 | Liver Metastasi... Colorectal Canc... | TACE + folfox 4 TAC + folfox4 | 18 Years - 75 Years | Fudan University | |
| TACE With Irinotecan Drug-eluting Beads and Intravenous (IV) Cetuximab in Refractory Colorectal Cancer | NCT01060423 | Colorectal Canc... | Cetuximab Irinotecan Irinotecan elut... | 18 Years - | Martin-Luther-Universität Halle-Wittenberg | |
| Avastin in Combination With Chemotherapy for RAS Mutant Unresectable Colorectal Liver-limited Metastases | NCT01972490 | Colorectal Neop... | avastin mFOLFOX6 | 18 Years - 75 Years | Fudan University | |
| LT for Unresectable Colorectal Liver Metastasis | NCT04874259 | Liver Metastasi... | Living donor li... | 19 Years - | Seoul National University Hospital | |
| Safety and Efficacy of Polyvinyl Alcohol Sodium Acrylate Embolization Microspheres for CRLM | NCT06021015 | Colorectal Canc... | Irinotecan and ... Irinotecan and ... | 18 Years - 80 Years | Zhongda Hospital | |
| Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM | NCT03127072 | Colorectal Canc... | Radiofrequency ... chemotherapy ± ... | 18 Years - 75 Years | Fudan University | |
| Study of NS-9 in Patients With Liver Metastases | NCT00094003 | Liver Neoplasms Neoplasm Metast... Local Neoplasm ... | NS-9 [Poly I: P... | 18 Years - | NS Pharma, Inc. | |
| Total Preoperative MR Diagnostic Evaluation Versus Standard Diagnostic Evaluation in Patients With Rectal Cancer | NCT01544452 | Rectal Cancer Liver Metastasi... | MR colonography... Standard diagno... | 18 Years - | Herlev Hospital | |
| Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM | NCT03127072 | Colorectal Canc... | Radiofrequency ... chemotherapy ± ... | 18 Years - 75 Years | Fudan University | |
| HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma | NCT06184841 | Hepatic Arteria... Liver Metastase... Esophageal Squa... | HAIC combined w... | 18 Years - 75 Years | Peking University Cancer Hospital & Institute | |
| Neoadjuvant Study of Recombinant Vaccinia Virus to Treat Metastatic Colorectal Carcinoma in Patients Undergoing Complete Resection of Liver Tumors | NCT01329809 | Colorectal Carc... | Recombinant Vac... | 18 Years - | Jennerex Biotherapeutics | |
| Phase 2 Study of Thermodox as Adjuvant Therapy With Thermal Ablation (RFA) in Treatment of Metastatic Colorectal Cancer(mCRC) | NCT01464593 | Colon Cancer Li... | Lyso-Thermosens... 5% Dextrose Sol... ThermoDox | 18 Years - | Imunon | |
| Intrahepatic Chemotherapy to Patients With Non-resectable Liver Metastases From Solid Tumor | NCT01511146 | Liver Metastasi... | Oxaliplatin Mitomycin + Gem... | 18 Years - | Copenhagen University Hospital at Herlev | |
| Efficacy of HIFU-AR on Blood Loss Reduction in Patients With Liver Metastases Requiring Hepatectomy | NCT02728167 | Liver Metastasi... | Pre-coagulation... | 18 Years - | Centre Leon Berard | |
| Treatment Outcomes of Hepatic Metastasis After FOLFOX-4 Therapy | NCT00610636 | Colorectal Canc... | Hepatic resecti... | 18 Years - 80 Years | National Taiwan University Hospital | |
| EPA for Metastasis Trial 2 | NCT03428477 | Liver Metastasi... Colon Cancer | Icosapent Ethyl Placebo | 18 Years - | University of Leeds | |
| Feasibility Study of Neoadjuvant Chemotherapy Modified FOLFOX6 for Resectable Liver Metastases of Colorectal Cancers | NCT00594529 | Colorectal Canc... Liver Metastasi... | Surgery | 20 Years - 80 Years | Kyoto University Hospital | |
| Hepatic Artery Infusion With Oxaliplatin | NCT00244348 | Colorectal Canc... Metastasis Liver Cancer | Oxaliplatin (vi... 5 Fluorouracil ... | 18 Years - | Medical College of Wisconsin | |
| Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI | NCT00820456 | Colorectal Neop... Hepatic Neoplas... | DCE-MRI | 18 Years - | American College of Radiology | |
| The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver | NCT01785212 | Liver Neoplasms Liver Metastasi... Liver Hemangiom... Echinococcosis,... | Stapler CUSA (Cavitron ... | 18 Years - 70 Years | Medical University of Vienna | |
| Effects of Acupoint Electro-stimulation on Preventing Nausea and Vomiting Induced by Cisplatin or Oxaliplatin | NCT00430313 | Liver Cancer Liver Metastasi... | Electro-Stimula... Electro-Stimula... | 18 Years - 75 Years | M.D. Anderson Cancer Center | |
| Paclitaxel Administered by HAI to Patients With Advanced Cancer and Dominant Liver Involvement | NCT00508326 | Advanced Cancer | Paclitaxel | 13 Years - | M.D. Anderson Cancer Center | |
| Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers | NCT03801915 | Colon Cancer Pancreatic Canc... Cholangiocarcin... Metastatic Colo... Liver Metastasi... | MVT-5873 pancreatectomy ... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| A Phase II Study of Cabozantinib (XL184) Therapy in Castrate Resistant Prostate Cancer (CRPC) With Visceral Metastases | NCT01834651 | Prostate Cancer | Cabozantinib | 18 Years - | Cedars-Sinai Medical Center | |
| Liver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer | NCT03494946 | Liver Metastase... Colorectal Canc... | Liver transplan... Chemotherapy | 18 Years - | Oslo University Hospital | |
| Study Comparing HAI Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM | NCT03125161 | Colorectal Aden... | HAI chemotherapy ± ... | 18 Years - 75 Years | Fudan University | |
| Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors | NCT00028405 | Liver Metastasi... Pelvic Cancer Head and Neck C... Sarcoma Rectal Cancer Breast Cancer Colorectal Canc... Mouth Cancer | LS 11(Taporfin ... Lumaflex Light ... | 18 Years - | Light Sciences LLC | |
| Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients | NCT05068531 | Colorectal Canc... | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | ||
| Optimization of Health Expenditure in Liver Surgery | NCT01715402 | Hepatocellular ... Hilar Cholangio... Intra Hepatic C... Liver Metastasi... | liver surgery | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
| Preoperative Transhepatic Arterial Chemotherapy (TAC) in the Treatment of Liver Metastasis of Resectable Colorectal Cancer | NCT00874406 | Colorectal Canc... | tac + folfox4 folfox4 | 18 Years - 75 Years | Fudan University | |
| Compare FOFLOX4 in Preoperative and Postoperative and Postoperative in Resectable Liver Metastasis Colorectal Cancer (MCC) | NCT01035385 | Colorectal Canc... Liver Metastasi... | FOFLOX4 | 18 Years - 80 Years | Guangdong Provincial People's Hospital | |
| Study Comparing HAI Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM | NCT03125161 | Colorectal Aden... | HAI chemotherapy ± ... | 18 Years - 75 Years | Fudan University | |
| Transarterial Radioembolisation in Comparison to Transarterial Chemoembolisation in Uveal Melanoma Liver Metastasis | NCT02936388 | Uveal Melanoma | SIRT DSM-TACE | 18 Years - 99 Years | Charite University, Berlin, Germany | |
| Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases | NCT00083785 | Liver Metastasi... Colorectal Neop... Liver Neoplasms Neoplasm Metast... | Talaporfin sodi... LED-based light... Light emitting ... Photodynamic th... Phototherapy Chemotherapy | 18 Years - | Light Sciences LLC | |
| Radiomics Assess of Bevacizumab Plus Chemo in Colorectal Cancer Liver Metastases | NCT04213222 | Colon Cancer Rectal Cancer Liver Metastase... | Bevacizumab | 18 Years - 80 Years | Peking University People's Hospital | |
| Influence of Neoadjuvant Therapy on the Resectability of Hepatic Metastases From Colorectal Cancers | NCT00172159 | Colorectal Canc... | Hepatic resecti... | 18 Years - 75 Years | National Taiwan University Hospital | |
| Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancer | NCT01856322 | Colorectal Canc... Liver Metastasi... Colorectal Aden... | Sulindac Placebo Validate assays... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Neo-adjuvant Peptide Receptor Mediated Radiotherapy With 177Lutetium in Front of Curative Intended Liver Transplantation in Patients With Hepatic Metastasis of Neuroendocrine Tumors (NEO-LEBE) | NCT01201096 | Liver Metastasis Neuroendocrine ... | 177Lutetium Liver transplan... | 18 Years - 60 Years | University of Jena | |
| Gastric Cancer Liver Metastasis Cohort of China | NCT04574245 | Stomach Neoplas... Neoplasm Metast... | Gastrectomy; He... | 18 Years - | Chinese PLA General Hospital | |
| To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation | NCT04417010 | KRAS Gene Colorectal Canc... Liver Metastasi... Safe Margin Radiofrequency ... | Radiofrequency ... | 18 Years - | Peking University Cancer Hospital & Institute | |
| Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases Treated by Chemotherapy | NCT02597348 | Liver Metastasi... Colorectal Canc... Metastasis | Liver Transplan... | 18 Years - 65 Years | Assistance Publique - Hôpitaux de Paris | |
| TATE and Pembrolizumab (MK3475) in mCRC and NSCLC | NCT04701476 | Colorectal Canc... | TATE and pembro... TAS-102 pill Regorafenib Pil... | 18 Years - | Teclison Ltd. | |
| Neo-adjuvant Peptide Receptor Mediated Radiotherapy With 177Lutetium in Front of Curative Intended Liver Transplantation in Patients With Hepatic Metastasis of Neuroendocrine Tumors (NEO-LEBE) | NCT01201096 | Liver Metastasis Neuroendocrine ... | 177Lutetium Liver transplan... | 18 Years - 60 Years | University of Jena | |
| NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy | NCT03589339 | Radiotherapy Immunotherapy Microsatellite ... Metastasis From... Squamous Cell C... Metastasis From... Metastatic Rena... Metastasis From... Metastatic Trip... Metastatic NSCL... Metastasis From... | NBTXR3 SABR Nivolumab Pembrolizumab | 18 Years - | Nanobiotix | |
| ALPPS (Liver Partition and Portal Vein Ligation) for Two-stage Hepatectomy for Colorectal Liver Metastasis | NCT01842971 | Colorectal Canc... | two stage hepat... | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
| Hepatic Arterial Infusion Oxaliplatin, Capecitabine With or Without Bevacizumab | NCT01213238 | Advanced Cancer... | Oxaliplatin Capecitabine Bevacizumab | 18 Years - | M.D. Anderson Cancer Center | |
| Perioperative Chemotherapy With Herceptin For Potentially Resectable HER-2 Positive Gastric Cancer With Liver Metastasis | NCT02380131 | HER-2 Positive ... Liver Metastasi... | Oxaliplatin plu... Herceptin | 18 Years - 75 Years | Hebei Medical University | |
| A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis | NCT05359393 | Advanced Rectal... Liver Metastasi... Pulmonary Metas... Microsatellite ... | a combination t... | 18 Years - 75 Years | Fudan University | |
| Hepatic Arterial Infusion Oxaliplatin, Capecitabine With or Without Bevacizumab | NCT01213238 | Advanced Cancer... | Oxaliplatin Capecitabine Bevacizumab | 18 Years - | M.D. Anderson Cancer Center | |
| Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases | NCT01836653 | Liver Only Meta... | Bevacizumab Cetuximab L-OHP l-LV 5-FU 5-FU | 20 Years - 80 Years | EPS Corporation | |
| Cryoablation Combined With Sintilimab Plus Lenvatinib In Previously Treated Unresectable Liver Metastasis From Solid Tumors | NCT05098847 | Liver Metastasi... | Sintilimab Lenvatinib Cryoablation | 18 Years - | Fudan University | |
| Dynamic Contrast-enhanced MRI Combined With IVIM-DWI for Early Prediction of Chemosensitivity in Liver MBC | NCT05550090 | Metastatic Brea... | Chemotherapy | 18 Years - | Zhejiang Cancer Hospital | |
| Immunotherapy Using Pluripotent Killer-Human Epidermal Growth Factor Receptor-2 (PIK-HER2) Cells for the Treatment of Advanced Gastric Cancer With Liver Metastasis | NCT02632201 | Liver Metastasi... Gastric Cancer | PIK-HER2 DC-PMAT | 18 Years - 65 Years | Second Military Medical University | |
| Hepatic Arterial Infusion of Nab-Paclitaxel in Patients With Metastatic Melanoma in the Liver | NCT00833807 | Melanoma Liver Metastasi... | Nab-Paclitaxel ... | 18 Years - | M.D. Anderson Cancer Center | |
| A Clinical Study of T3011 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer | NCT06283303 | Colorectal Canc... | T3011 hepatic a... toripalimab regorafenib | 18 Years - | China Medical University, China | |
| Pringle Manoeuvre Versus Portal Vein Clamping for Liver Resection | NCT02042794 | Liver Metastasi... | 18 Years - | The Leeds Teaching Hospitals NHS Trust | ||
| Surgical or Medical Treatment of Breast Cancer Metastasis: A Multicentre Observational Study | NCT06093022 | Breast Cancer Liver Metastase... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | ||
| Efficacy of HIFU-AR on Blood Loss Reduction in Patients With Liver Metastases Requiring Hepatectomy | NCT02728167 | Liver Metastasi... | Pre-coagulation... | 18 Years - | Centre Leon Berard | |
| Liver Transplantation and Colorectal Cancer | NCT01479608 | Colorectal Canc... Liver Metastasi... | Liver transplan... | 18 Years - | Oslo University Hospital | |
| Effects of Acupoint Electro-stimulation on Preventing Nausea and Vomiting Induced by Cisplatin or Oxaliplatin | NCT00430313 | Liver Cancer Liver Metastasi... | Electro-Stimula... Electro-Stimula... | 18 Years - 75 Years | M.D. Anderson Cancer Center | |
| Evaluation of Suspected Liver Pathology in Patients With Contraindications for Contrast Enhanced CT and/or MRI | NCT02651090 | Liver Metastasi... Liver Mass | Sonazoid | 18 Years - 100 Years | Northeastern Ohio Radiology Research and Education Fund | |
| Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer | NCT01762813 | Colorectal Canc... | open and laparo... | 18 Years - | Helse Stavanger HF | |
| Clinical Outcome and Future Liver Remnant Regenerative Response in Laparoscopic Versus Open ALPPS | NCT04868149 | Liver Cancer | Associating Liv... | 18 Years - | The University of Hong Kong | |
| Phase I:Decitabine by Hepatic Arterial Infusion(HAI) in Unresectable Liver Metastases Colorectal Cancer (CRC) | NCT02316028 | Liver Metastasi... Colorectal Canc... | Decitabine | 18 Years - | Universitair Ziekenhuis Brussel | |
| Preoperative Chemotherapy With Bevacizumab For Potentially Resectable Gastric Cancer With Liver Metastasis | NCT01962376 | Gastric Cancer Liver Metastasi... | Oxaliplatin;Cap... Oxaliplatin;Cap... | 18 Years - 75 Years | Hebei Medical University | |
| Clinical Outcome and Future Liver Remnant Regenerative Response in Laparoscopic Versus Open ALPPS | NCT04868149 | Liver Cancer | Associating Liv... | 18 Years - | The University of Hong Kong | |
| Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease | NCT04595266 | Colorectal Canc... Liver Metastasi... | FOLFOX regimen Anti-EGFR or Be... LIVERPEARLS-Iri... | 18 Years - | Grupo Espanol Multidisciplinario del Cancer Digestivo | |
| A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Advanced Solid Tumors With Liver Metastases | NCT01120288 | Neoplasms Liver Metastase... | EZN-2968 | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer | NCT02380443 | Colorectal Canc... | AlloStim Cryoablation | 18 Years - 80 Years | Immunovative Therapies, Ltd. | |
| Paclitaxel Administered by HAI to Patients With Advanced Cancer and Dominant Liver Involvement | NCT00508326 | Advanced Cancer | Paclitaxel | 13 Years - | M.D. Anderson Cancer Center | |
| A Clinical Study of T3011 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer | NCT06283303 | Colorectal Canc... | T3011 hepatic a... toripalimab regorafenib | 18 Years - | China Medical University, China | |
| Study of NS-9 in Patients With Liver Metastases | NCT00094003 | Liver Neoplasms Neoplasm Metast... Local Neoplasm ... | NS-9 [Poly I: P... | 18 Years - | NS Pharma, Inc. | |
| Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancer | NCT01856322 | Colorectal Canc... Liver Metastasi... Colorectal Aden... | Sulindac Placebo Validate assays... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Adjuvant Xeloda Plus Eloxatin +/- Avastin After Radical Resection of Liver Metastasis of Colorectal Cancer | NCT00394992 | Colorectal Canc... Liver Metastase... | oxaliplatin+cap... Oxaliplatin+cap... | 18 Years - | Dutch Colorectal Cancer Group | |
| AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer | NCT02380443 | Colorectal Canc... | AlloStim Cryoablation | 18 Years - 80 Years | Immunovative Therapies, Ltd. |
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