Spots Global Cancer Trial Database for Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
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Trial Identification
Brief Title: Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
Official Title: Evaluation of the Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations of Poor Prognosis
Study ID: NCT03243019
Study Description
Brief Summary: To evaluate the efficacy of Rapamycin in extended cervicofacial lymphatic malformations in pediatric patients. Rapamycin is administered oral for a 6 month period. The success rate is determined by volume reduction superior to 1/5e of the initial volume measured by MRI, impact on QOL and reduction of bleeding in case of mucosal involvement.
Detailed Description:
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Hôpital Jeanne de Flandres, CHU, Lille, , France
Hu Robert Debre Aphp - Paris, Paris, , France
Contact Details
Name: Pierre Fayoux, MD
Affiliation: University Hospital, Lille
Role: PRINCIPAL_INVESTIGATOR
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