Spots Global Cancer Trial Database for lymphatic malformation
Every month we try and update this database with for lymphatic malformation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations | NCT06239480 | Microcystic Lym... | QTORIN 3.9% Rap... Placebo | 6 Years - | Palvella Therapeutics, Inc. | |
| A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations | NCT06239480 | Microcystic Lym... | QTORIN 3.9% Rap... Placebo | 6 Years - | Palvella Therapeutics, Inc. | |
| Weekly Sirolimus Therapy | NCT04861064 | Venous Malforma... Lymphatic Malfo... | Sirolimus | 2 Years - | Medical University of South Carolina | |
| Registry for Vascular Anomalies Associated With Coagulopathy | NCT00576888 | Multifocal Lymp... Cutaneovisceral... Vascular Anomal... Hemangiomas | no intervention | - | Medical College of Wisconsin | |
| Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age | NCT05871970 | Lymphatic Malfo... | TARA-002 | 6 Months - 18 Years | Protara Therapeutics | |
| A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations | NCT05983159 | Slow-Flow Vascu... Fast-Flow Vascu... Vascular Malfor... Venous Malforma... Lymphatic Malfo... Lymphatic Malfo... Lymphangioma Arteriovenous M... Venous Malforma... Cystic Hygroma Vascular Anomal... Vascular Anomal... PI3K Gene Mutat... MAP2K1 Gene Mut... PIK3CA-related ... Arteriovenous M... KRAS G12C KRAS G12D | Alpelisib Mirdametinib | 2 Years - | Murdoch Childrens Research Institute | |
| Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations | NCT03243019 | Lymphatic Malfo... Pediatric | rapamycin MRI Rapamycin dosag... | - 18 Years | University Hospital, Lille | |
| First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene Mutations | NCT04409145 | Venous Malforma... Lymphatic Malfo... Venolymphatic M... | VT30 | 18 Years - 60 Years | Venthera, Inc., a BridgeBio company | |
| A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations | NCT06239480 | Microcystic Lym... | QTORIN 3.9% Rap... Placebo | 6 Years - | Palvella Therapeutics, Inc. | |
| A Prospective Study on the Treatment of cLM Based on ICG Imaging | NCT06275022 | Lymphatic Malfo... | Inflow occlusio... Perforation of ... Indocyanine gre... Partial resecti... | 30 Days - 16 Years | Nanjing Children's Hospital | |
| Topical Sirolimus in Cutaneous Lymphatic Malformations | NCT03972592 | Vascular Malfor... Lymphatic Malfo... | Topical 0.1% Si... Topical Vehicle | 6 Years - | University Hospital, Tours | |
| Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients | NCT06437158 | Lymphatic Malfo... | Bleomycin | - 14 Years | West China Hospital | |
| A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations | NCT05983159 | Slow-Flow Vascu... Fast-Flow Vascu... Vascular Malfor... Venous Malforma... Lymphatic Malfo... Lymphatic Malfo... Lymphangioma Arteriovenous M... Venous Malforma... Cystic Hygroma Vascular Anomal... Vascular Anomal... PI3K Gene Mutat... MAP2K1 Gene Mut... PIK3CA-related ... Arteriovenous M... KRAS G12C KRAS G12D | Alpelisib Mirdametinib | 2 Years - | Murdoch Childrens Research Institute | |
| A Prospective Study on the Treatment of cLM Based on ICG Imaging | NCT06275022 | Lymphatic Malfo... | Inflow occlusio... Perforation of ... Indocyanine gre... Partial resecti... | 30 Days - 16 Years | Nanjing Children's Hospital | |
| National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS) | NCT05563831 | PIK3CA-related ... CLOVES Syndrome Klippel Trenaun... Megalencephaly MCAP Macrodactyly Vascular Malfor... Lymphatic Malfo... Venous Malforma... | national regist... | - | Institut National de la Santé Et de la Recherche Médicale, France | |
| Topical Sirolimus in Cutaneous Lymphatic Malformations | NCT03972592 | Vascular Malfor... Lymphatic Malfo... | Topical 0.1% Si... Topical Vehicle | 6 Years - | University Hospital, Tours | |
| A Pharmacokinetic, Pharmacodynamic, Safety and Tolerability Study of CERC-006 in Adults With Complex Lymphatic Malformations | NCT04994002 | Lymphatic Malfo... | CERC-006 | 18 Years - 31 Years | Avalo Therapeutics, Inc. |
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