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Brief Title: A Study of BIND-014 Given to Patients With Advanced or Metastatic Cancer
Official Title: A Phase 1 Open Label, Safety, Pharmacokinetic and Pharmacodynamic Dose Escalation Study of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension), Given by Intravenous Infusion to Patients With Advanced or Metastatic Cancer
Study ID: NCT01300533
Brief Summary: The goal of this Phase 1 clinical research study is to find the highest safe dose of BIND-014 that can be given in the treatment of patients with advanced or metastatic cancer.
Detailed Description: The study is designed to explore the safety, tolerability, pharmacokinetics and pharmacodynamics of BIND-014 and define a recommended Phase 2 dose of BIND-014. All cycles of therapy will consist of the patient taking BIND-014 intravenously once every three weeks or weekly for three out of four weeks.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Investigational Site #01, Scottsdale, Arizona, United States
Investigational Site #02, Greenbrae, California, United States
Investigational Site #04, Los Angeles, California, United States
Investigational Site #06, Fort Meyers, Florida, United States
Investigational Site #03, Detriot, Michigan, United States
Investigational Site #05, Nashville, Tennessee, United States