Spots Global Cancer Trial Database for Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer.
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Trial Identification
Brief Title: Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer.
Official Title: A Phase III Multi-Center Randomized Clinical Trial to Evaluate the Safety and Efficacy of CoFactor and 5-Fluorouracil (5-FU) Plus Bevacizumab Versus Leucovorin and 5-FU Plus Bevacizumab as Initial Treatment for Metastatic Colorectal Carcinoma
Study ID: NCT00337389
Study Description
Brief Summary: To compare the progression-free survival time (PFS) in patients treated with 5-FU modulated with CoFactor (plus bevacizumab) to 5-FU modulated with leucovorin (plus bevacizumab) in patients with Metastatic Colorectal Cancer.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Center In, Florence, Alabama, United States
Research Center In, Anaheim, California, United States
Research Center In, Apple Valley, California, United States
Research Center In, Beverly Hills, California, United States
Research Center In, Irvine, California, United States
Research Center In, Mission Hills, California, United States
Research Center In, Poway, California, United States
Research Center In, Rancho Mirage, California, United States
Mercy General Hospital, Sacramento, California, United States
Research Center In, Sacramento, California, United States
Research Center In, San Diego, California, United States
Research Site In, San Diego, California, United States
Research Center In, Vista, California, United States
Research Center In, Boynton Beach, Florida, United States
Research Center In, Merritt Island, Florida, United States
Research Center In, Port St. Lucie, Florida, United States
Research Center In, Tarpon Springs, Florida, United States
Research Center In, Gurnee, Illinois, United States
Research Center In, Joliet, Illinois, United States
Research Center In, Skokie, Illinois, United States
Research Center In, Indianapolis, Indiana, United States
Research Center In, Wichita, Kansas, United States
Research Center In, Hazard, Kentucky, United States
Research Center In, Baltimore, Maryland, United States
Research Center In, Flint, Michigan, United States
Research Center In, Freesoil, Michigan, United States
Research Center In, Grand Rapids, Michigan, United States
Research Center In, Port Huron, Michigan, United States
Research Center In, Jackson, Mississippi, United States
Research Center In, Henderson, Nevada, United States
Research Center In, Las Vegas, Nevada, United States
Research Center In, Reno, Nevada, United States
Research Center In, Cherry Hill, New Jersey, United States
Research Center In, Farmington, New Mexico, United States
Research Center In, East Setauket, New York, United States
Research Center In, Greenville, North Carolina, United States
Research Center In, Middletown, Ohio, United States
Research Center In, Cranston, Rhode Island, United States
Research Center In, Charleston, South Carolina, United States
Research Center In, Columbia, South Carolina, United States
Research Center In, Chattanooga, Tennessee, United States
Research Center In, Collierville, Tennessee, United States
Research Center In, Fort Worth, Texas, United States
Research Center In, Ogden, Utah, United States
Research Center In, Lacey, Washington, United States
Research Center In, Walla Walla, Washington, United States
Research Center In, Zrenjanin, , Former Serbia and Montenegro
Contact Details
Name: M. Wasif Saif, MD, MBBS
Affiliation: Yale University
Role: STUDY_CHAIR
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