Spots Global Cancer Trial Database for A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
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Trial Identification
Brief Title: A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
Official Title: AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE 3 STUDY OF FIRST-LINE ENCORAFENIB PLUS CETUXIMAB WITH OR WITHOUT CHEMOTHERAPY VERSUS STANDARD OF CARE THERAPY WITH A SAFETY LEAD-IN OF ENCORAFENIB AND CETUXIMAB PLUS CHEMOTHERAPY IN PARTICIPANTS WITH METASTATIC BRAF V600E-MUTANT COLORECTAL CANCER
Study ID: NCT04607421
Conditions
Study Description
Brief Summary: The purpose of this study is to evaluate two study medicines (encorafenib plus cetuximab) taken alone or together with standard chemotherapy for the potential treatment of colorectal cancer that: * has spread to other parts of the body (metastatic); * has a certain type of abnormal gene called "BRAF"; and * has not received prior treatment. Participants in this study will receive one of the following study treatments: * Encorafenib plus cetuximab: These participants will receive encorafenib by mouth at home every day and cetuximab once every two weeks by intravenous (IV) infusion (an injection into the vein) at the study clinic. * Encorafenib plus cetuximab with chemotherapy: These participants will receive encorafenib and cetuximab in the way described in the bullet above. Additionally, they will receive standard chemotherapy by IV infusion and oral treatment at home. * Chemotherapy alone: These participants will receive chemotherapy, the standard treatment for this condition, by IV infusion at the study clinics and oral treatment at home. This study is currently enrolling participants who will receive either encorafenib plus cetuximab with chemotherapy or chemotherapy alone. The study team will monitor how each participant responds to the study treatment for up to about 3 years.
Detailed Description: The purpose of the study is to evaluate whether encorafenib plus cetuximab (EC), alone or in combination with chemotherapy, can improve clinical outcomes relative to current standard of-care chemotherapy in participants with previously untreated BRAF V600E-mutant mCRC. Since encorafenib has not previously been combined with chemotherapy, the tolerability and PK of EC in combination with mFOLFOX6 and in combination with FOLFIRI will be evaluated in separate cohorts in the safety lead-in portion of the trial in order to identify which chemotherapy combination is to be used in the Phase 3 portion of the study.
Keywords
Eligibility
Minimum Age: 16 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Mayo Clinic - Phoenix Oncology Pharmacy, Phoenix, Arizona, United States
Mayo Clinic Hospital, Phoenix, Arizona, United States
Mayo Clinic in Arizona - Scottsdale, Scottsdale, Arizona, United States
Tower Hematology Oncology Medical Group (THO), Beverly Hills, California, United States
Keck Hospital of USC, Los Angeles, California, United States
LAC & USC Medical Center, Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
USC/Norris Comprehensive Cancer Center / Investigational Drug Services, Los Angeles, California, United States
USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States
Cedars- Sinai Medical Center, Los Angeles, California, United States
Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, United States
Cedars-Sinai Medical Center, Los Angeles, California, United States
Keck Hospital of USC Pasadena, Pasadena, California, United States
Torrance Memorial Medical Center (TMMC), Torrance, California, United States
Georgetown University Medical Center, Washington, District of Columbia, United States
Medstar Georgetown University Hospital, Washington, District of Columbia, United States
Mount Sinai Comprehensive Cancer Center, Aventura, Aventura, Florida, United States
Sylvester Comprehensive Cancer Center- The Lennar Foundation Medical Center, Coral Gables, Florida, United States
Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center, Fort Lauderdale, Florida, United States
Mayo Clinic Florida, Jacksonville, Florida, United States
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States
Mount Sinai Medical Center, Miami Beach, Florida, United States
Sylvester Comprehensive Cancer Center, Miami, Florida, United States
Baptist Hospital of Miami, Miami, Florida, United States
Miami Cancer Institute, Miami, Florida, United States
Orlando Health Cancer Institute, Orlando, Florida, United States
Orlando Health, Inc., Orlando, Florida, United States
Orlando Health, Inc, Orlando, Florida, United States
BRCR Global, Plantation, Florida, United States
BRCR Medical Center Inc., Plantation, Florida, United States
Lewis Cancer & Research Pavilion at St Joseph's/Candler Health System, Savannah, Georgia, United States
Lewis Cancer & Research Pavilion Pharmacy, Savannah, Georgia, United States
St. Joseph's/Candler Health System, Inc., Savannah, Georgia, United States
Summit Cancer Care, P.C., Savannah, Georgia, United States
Summit Cancer Care, Savannah, Georgia, United States
St. Joseph's/Candler Health System, Inc., Savannah, Georgia, United States
UChicago Medicine - River East, Chicago, Illinois, United States
The University of Chicago Medical Center, CCD - Investigational Drug Service Pharmacy, Chicago, Illinois, United States
University of Chicago Medical Center, Chicago, Illinois, United States
UChicago Medicine at Ingalls - Flossmoor, Flossmoor, Illinois, United States
UChicago Medicine Ingalls Memorial, Harvey, Illinois, United States
University of Chicago Comprehensive Cancer Center at Silver Cross Hospital, New Lenox, Illinois, United States
The University of Chicago Medicine Center for Advanced Care Orland Park, Orland Park, Illinois, United States
UChicago Medicine at Ingalls - Tinley Park, Tinley Park, Illinois, United States
Ochsner Clinic Foundation Research Pharmacy, New Orleans, Louisiana, United States
Ochsner Clinic Foundation, New Orleans, Louisiana, United States
University of Michigan Hospitals, Ann Arbor, Michigan, United States
University of Michigan, Ann Arbor, Michigan, United States
Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota, United States
Mayo Clinic Rochester, Rochester, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
Siteman Cancer Center - West County, Creve Coeur, Missouri, United States
Siteman Cancer Center - North County, Florissant, Missouri, United States
Barnes- Jewish Hospital, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Siteman Cancer Center - South County, Saint Louis, Missouri, United States
Siteman Cancer Center - St Peters, Saint Peters, Missouri, United States
St Vincent Healthcare, Billings, Montana, United States
St. Vincent Frontier Cancer Center, Billings, Montana, United States
Oncology Hematology West PC dba Nebraska Cancer Specialists, Omaha, Nebraska, United States
Oncology Hematology West PC dba Nebraska Cancer Specialists, Omaha, Nebraska, United States
Oncology Hematology West PC dba Nebraska Cancer Specialists, Omaha, Nebraska, United States
Oncology Hematology West, PC dba Nebraska Cancer Specialists - IP Storage, Omaha, Nebraska, United States
Oncology Hematology West PC dba Nebraska Cancer Specialists, Papillion, Nebraska, United States
Memorial Sloan Kettering Cancer Center - Basking Ridge, Basking Ridge, New Jersey, United States
Summit Medical Group, Berkeley Heights, New Jersey, United States
Summit Medical Group, Florham Park, New Jersey, United States
Memorial Sloan Kettering Cancer Center- Monmouth, Middletown, New Jersey, United States
Memorial Sloan Kettering Cancer Center- Bergen, Montvale, New Jersey, United States
North Shore Hematology Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists, Babylon, New York, United States
North Shore Hematology Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists, Bronx, New York, United States
Memorial Sloan Kettering Cancer Center Commack, Commack, New York, United States
Memorial Sloan Kettering Cancer Center - Westchester, Harrison, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
North Shore Hematology Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists, New York, New York, United States
Memorial Sloan Kettering Cancer Center - Main Campus, New York, New York, United States
North Shore Hematology Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists, Patchogue, New York, United States
North Shore Hematology Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists, Port Jefferson Station, New York, United States
North Shore Hematology Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists, Riverhead, New York, United States
Memorial Sloan Kettering Cancer Center- Nassau, Uniondale, New York, United States
Carolinas Medical Center, Charlotte, North Carolina, United States
Carolinas Medical Center Investigational Drug Services, Charlotte, North Carolina, United States
Levine Cancer Institute, Charlotte, North Carolina, United States
Atrium Health Mercy, Charlotte, North Carolina, United States
Atrium Health Pineville, Charlotte, North Carolina, United States
Levine Cancer Institute - Southpark, Charlotte, North Carolina, United States
Atrium Health University City, Charlotte, North Carolina, United States
Levine Cancer Institute University City, Charlotte, North Carolina, United States
Atrium Health Cabarrus, Concord, North Carolina, United States
Levine Cancer Institute - Concord, Concord, North Carolina, United States
Atrium Health Union, Monroe, North Carolina, United States
Cleveland Clinic Taussig Cancer Center Investigational Pharmacy, Cleveland, Ohio, United States
Cleveland Clinic, Cleveland, Ohio, United States
Investigational Drug Service, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
The Ohio State University James Cancer Hospital and Solove Research Institute, Columbus, Ohio, United States
Stefanie Spielman Comprehensive Breast Cancer, Columbus, Ohio, United States
Martha Morehouse Medical Plaza, Columbus, Ohio, United States
The James Outpatient Care West Campus, Columbus, Ohio, United States
University of Oklahoma Health Sciences Center, OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Providence Cancer Institute Franz Clinic, Portland, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Providence Onc and Heme Care Clinic - Westside, Portland, Oregon, United States
Providence Oncology and Hematology Care Clinic - Westside, Portland, Oregon, United States
Providence St Vincent Medical Center, Portland, Oregon, United States
Providence St. Vincent Medical Center, Portland, Oregon, United States
AHN Cancer Institute at Jefferson Hospital, Jefferson Hills, Pennsylvania, United States
AHN Cancer Institute Forbes Hospital, Monroeville, Pennsylvania, United States
AHN Cancer Institute - Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
AHN Cancer Institute Pharmacy, Pittsburgh, Pennsylvania, United States
AHN Cancer Institute West Penn Hospital, Pittsburgh, Pennsylvania, United States
UPMC Hillman Cancer Center Investigational Drug Service, Pittsburgh, Pennsylvania, United States
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
Wexford Health and Wellness Pavilion, Wexford, Pennsylvania, United States
Vanderbilt Health Clinic at Walgreens Clarksville, Clarksville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Cool Springs, Franklin, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Gallatin, Gallatin, Tennessee, United States
The West Clinic. PLLC. dba West Cancer Center, Germantown, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Hendersonville, Hendersonville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Hermitage, Hermitage, Tennessee, United States
Vanderbilt Health Clinic at Walgreens La Vergne, La Vergne, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Lebanon, Lebanon, Tennessee, United States
The West Clinic PLLC dba West Cancer Center, Memphis, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Murfreesboro, Murfreesboro, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Belle Meade, Nashville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Nippers Corner, Nashville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Donelson, Nashville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Hart Lane, Nashville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Bellevue, Nashville, Tennessee, United States
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Henry-Joyce Cancer Center, Nashville, Tennessee, United States
Vanderbilt Oncology IDS Pharmacy, Nashville, Tennessee, United States
Vanderbilt Health Clinic at Walgreens Smyrna, Smyrna, Tennessee, United States
The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
VCU Health - Adult Outpatient Pavilion (AOP) Investigational Drug Services, Richmond, Virginia, United States
Virginia Commonwealth University, Richmond, Virginia, United States
VCU Health System, Investigational Drug Service Pharmacy, Richmond, Virginia, United States
Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, United States
Seattle Cancer Care Alliance, Seattle, Washington, United States
University of Washington Medical Center, Seattle, Washington, United States
University of Wisconsin Clinical Science Center, Madison, Wisconsin, United States
Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Centro Medico San Roque, San Miguel De Tucumán, Tucumán, Argentina
Centro Medico San Roque, Tucuman, Tucumán, Argentina
Instituto Médico Especializado Alexander Fleming, Ciudad Autónoma de Buenos Aires, , Argentina
Clinica Universitaria Reina Fabiola, Cordoba, , Argentina
Hospital Privado Centro Médico de Córdoba, Cordoba, , Argentina
Hospital Privado Centro Médico de Córdoba, Córdoba, , Argentina
Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia
Liverpool Hospital, Liverpool, New South Wales, Australia
Slade Pharmacy, Mount Kuring-Gai, New South Wales, Australia
GenesisCare - North Shore, St Leonards, New South Wales, Australia
GenesisCare North Shore, St Leonards, New South Wales, Australia
Royal Brisbane & Women's Hospital, Herston, Queensland, Australia
Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
The Queen Elizabeth Hospital, Adelaide, South Australia, Australia
Monash Health, Clayton, Victoria, Australia
Austin Health, Heidelberg, Victoria, Australia
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Alfred Health, Melbourne, Victoria, Australia
Université Libre de Bruxelles - Hôpital Erasme, Brussels, Bruxelles-capitale, Région DE, Belgium
Cliniques universitaires Saint-Luc, Brussels, Bruxelles-capitale, Région DE, Belgium
Grand Hôpital de Charleroi, Charleroi, Hainaut, Belgium
CHR Verviers East Belgium, Verviers, Liège, Belgium
AZ Groeninge Campus Kennedylaan, Kortrijk, West-vlaanderen, Belgium
ZNA Middelheim, Antwerpen, , Belgium
UZ Leuven, Leuven, , Belgium
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège, , Belgium
Hospital Bruno Born, Lajeado, RIO Grande DO SUL, Brazil
Hospital Bruno Born, Lajeado, RIO Grande DO SUL, Brazil
Hospital Bruno Born, Lajeado, RIO Grande DO SUL, Brazil
Hospital de Clinicas de Porto Alegre, Porto Alegre, RIO Grande DO SUL, Brazil
INCA, Rio de Janeiro, RJ, Brazil
Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rio de Janeiro, RJ, Brazil
Reichow - Centro de Ensino e Pesquisa, Blumenau, Santa Catarina, Brazil
Clínica de Neoplasias Litoral, Itajaí, Santa Catarina, Brazil
Hospital do Cancer de Barretos - Fundacao Pio XII, Barretos, SP, Brazil
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Faculdade de Medicina do ABC, Santo Andre, SP, Brazil
Fundacao do ABC-Faculdade de Medicina do ABC, Santo Andre, SP, Brazil
FUNDAÇÃO DO ABC - Faculdade de Medicina do ABC - Centro de Estudos e Pesquisas de Hematologia e Onc, Santo Andre, SP, Brazil
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Faculdade de Medicina do ABC, Santo André, SP, Brazil
Instituto do Cancer do Estado de Sao Paulo, ICESP, Sao Paulo, SP, Brazil
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, SÃO Paulo, Brazil
Medical School Famerp-HB-FUNFARME_Do not use - Duplicate facility, Sao jose do Rio Preto, SÃO Paulo, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, SÃO Paulo, Brazil
MHAT Uni Hospital OOD, Panagyurishte, Pazardzhik, Bulgaria
MHAT "Dr. Tota Venkova" AD, Gabrovo, , Bulgaria
Complex Oncology Center - Plovdiv EOOD, Plovdiv, , Bulgaria
MHAT Central Onco Hospital OOD, Plovdiv, , Bulgaria
Complex Oncology Center - Plovdiv EOOD, Plovdiv, , Bulgaria
Medical Center Nadezhda Clinical EOOD, Sofia, , Bulgaria
Acibadem City Clinic MHAT Tokuda, Sofia, , Bulgaria
University Multiprofile Hospital for Active Treatment Sofiamed, Sofia, , Bulgaria
Tom Baker Cancer Centre, Calgary, Alberta, Canada
Cross Cancer Institute, Edmonton, Alberta, Canada
Kingston Health Sciences Centre-Kingston General Hospital Site, Kingston, Ontario, Canada
London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Centre Intégré de Santé et de Services Sociaux (CISSS) de Laval / Hôpital de la Cité-de-la-Sant, Laval, Quebec, Canada
Jewish General Hospital, Montreal, Quebec, Canada
Anhui Provincial Cancer Hospital, Hefei, Anhui, China
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing, China
Beijing Cancer hospital, Beijing, Beijing, China
Beijing Hospital, Beijing, Beijing, China
Chongqing University Cancer Hospital, Chongqing, Chongqing, China
Fujian Medical University Union Hospital-1 Bingfanglou, Fuzhou, Fujian, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China
Henan provincial people's hospital, Zhengzhou, Henan, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China
The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China
Shengjing Hospital Of China Medical University, Shenyang, Liaoning, China
Jinan Central Hospital, Jinan, Shandong, China
Shandong province cancer hospital, Jinan, Shandong, China
The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
Shanghai Jiaotong University School of Medicine Ruijin Hospital, Shanghai, Shanghai, China
Shanghai General Hospital, Shanghai, Shanghai, China
Sichuan Province Cancer Hospital, Chengdu, Sichuan, China
Yunnan Cancer Hospital(The Third Affiliated Hospital of Kunming Medical University), Kunming, Yunnan, China
The second Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
Peking University First Hospital, Beijing, , China
Fudan University Shanghai Cancer Center, Shanghai, , China
Tianjin Union Medical Center, Tianjin, , China
Fakultní nemocnice Brno Bohunice, Brno, Brno-město, Czechia
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové, Czechia
Fakultni Thomayerova nemocnice, Prague, Praha 4, Czechia
Fakultni nemocnice Olomouc, Olomouc, , Czechia
Fakultni nemocnice v Motole, Praha 5, , Czechia
Fakultni nemocnice Bulovka, Praha 8, , Czechia
Aalborg Universitetshospital, Syd, Aalborg, Nordjylland, Denmark
Vejle Hospital-Sygehus Lillebaelt, Vejle, Syddanmark, Denmark
Vejle Sygehus, Vejle, Syddanmark, Denmark
Aalborg Universitetshospital, Aalborg, , Denmark
Rigshospitalet, Copenhagen, , Denmark
Herlev and Gentofte Hospital, Herlev, , Denmark
Odense University Hospital, Odense C, , Denmark
Docrates Syöpäsairaala, Helsinki, Nyland, Finland
Tampereen yliopistollinen sairaala, Tampere, Pirkanmaa, Finland
Helsinki University Central Hospital, Helsinki, , Finland
Oulu University Hospital, Oulu, , Finland
Satakunnan Keskussairaala, Pori, , Finland
Tampereen yliopistollinen sairaala, Tampere, , Finland
Turku University Hospital, Turku, , Finland
Muenchen Klinik Neuperlach, Klinik fuer Haematologie und Onkologie, Muenchen, Bayern, Germany
Institut für Klinisch Onkologische Forschung, Frankfurt, Hessen, Germany
Medizinische Hochschule Hannover, Hannover, Lower Saxony, Germany
Medizinische Hochschule Hannover, Hannover, Niedersachsen, Germany
Universitätsklinikum Leipzig, Leipzig, Sachsen, Germany
Radiologie Berlin, Berlin - Charlottenburg, , Germany
Onkologische Schwerpunktpraxis Kurfuerstendamm, Berlin, , Germany
Waage Apotheke, Berlin, , Germany
HELIOS Klinikum Berlin Buch GmbH, Berlin, , Germany
Helios Klinikum Berlin-Buch, Berlin, , Germany
Technische Universität Dresden, Medizinische Fakultät Carl Gustav Carus, Dresden, , Germany
Universitätsklinikum Carl Gustav Carus Dresden, Dresden, , Germany
Facharztzentrum Eppendorf, Hamburg, , Germany
ZytoService Deutschland GmbH, Standort-Hamburg-Jenfeld, Hamburg, , Germany
Radiologie im Israelitischen Krankenhaus, Hamburg, , Germany
Klinikum Oldenburg AöR, Oldenburg, , Germany
Klinikum Oldenburg AöR, Oldenburg, , Germany
Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi, India
Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi, India
Tata Memorial Hospital, Mumbai, Maharashtra, India
Deenanath Mangeshkar Hospital & Research Centre, Pune, Maharashtra, India
Sahyadri Speciality Hospital, Pune, Maharashtra, India
Bhakti Vedanta Hospital and Research Institute, Thane, Maharashtra, India
R K Birla Cancer Center, SMS Hospital, Jaipur, Rajasthan, India
Sawai Man Singh Medical College Hospital (SMS Hospital), Jaipur, Rajasthan, India
Azienda Ospedaliera Universitaria di Cagliari - Presidio Policlinico Universitario "D.Casula", Monserrato (CA), Cagliari, Italy
IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy
ASST Grande Ospedale Metropolitano Niguarda, Milan, Milano, Italy
Fondazione del Piemonte per l'Oncologia - Istituto di Candiolo IRCCS, Candiolo, Torino, Italy
Azienda Ospedaliero Universitaria San Luigi Gonzaga, Orbassano, Torino, Italy
Fondazione Poliambulanza Istituto Ospedaliero, Brescia, , Italy
Istituto Europeo di Oncologia IRCCS, Milano, , Italy
Azienda Ospedaliera Universitaria dell'Università "Luigi Vanvitelli" di Napoli, Napoli, , Italy
IRCCS Istituto Oncologico Veneto (IOV), Padova, , Italy
Azienda USL - IRCCS di Reggio Emilia - Arcispedale Santa Maria Nuova, Reggio Emilia, , Italy
Chiba cancer center, Chiba-shi, Chiba, Japan
National Cancer Center Hospital East, Kashiwa, Chiba, Japan
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime, Japan
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Kanazawa University Hospital, Kanazawa, Ishikawa, Japan
St. Marianna University Hospital, Kawasaki, Kanagawa, Japan
Kanagawa cancer center, Yokohama, Kanagawa, Japan
Aichi Cancer Center Hospital, Nagoya, Nagoya, Aichi, Japan
Osaka Prefectural Hospital Organization Osaka International Cancer Institute, Osaka-shi, Osaka, Japan
Kindai University Hospital, Osakasayama, Osaka, Japan
Osaka University Hospital, Suita, Osaka, Japan
Osaka Medical and Pharmaceutical University Hospital, Takatsuki, Osaka, Japan
Saitama Medical University International Medical Center, Hidaka-city, Saitama, Japan
Saitama Prefectural Cancer Center, Ina-machi, Saitama, Japan
Shizuoka Cancer Center, Nagaizumi, Shizuoka, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan
National Hospital Organization Kyushu Cancer Center, Fukuoka, , Japan
National Hospital Organization - Osaka National Hospital - Institute For Clinical Research, Osaka, , Japan
Keio university hospital, Tokyo, , Japan
National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of
Kyungpook National University Hospital, Daegu, Taegu-kwangyǒkshi, Korea, Republic of
Dong-A University Hospital, Busan, , Korea, Republic of
Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Chonnam National University Hwasun Hospital Pharmacy, Jeonnam, , Korea, Republic of
Chonnam National University Hwasun Hospital, Jeonnam, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Accelerium, S. de R.L. de C.V., Monterrey, Nuevo LEON, Mexico
Centro de Investigacion Clinica de Oaxaca, Oaxaca, , Mexico
Maastricht UMC+, Maastricht, Limburg, Netherlands
Catharina Ziekenhuis, Eindhoven, Noord-brabant, Netherlands
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL), Amsterdam, Noord-holland, Netherlands
Haaglanden Medisch Centrum, Leidschendam, Zuid-holland, Netherlands
Amsterdam UMC, location VUMc, Amsterdam, , Netherlands
Maastricht University Medical Center, Maastricht, , Netherlands
Universitair Medisch Centrum Utrecht, Utrecht, , Netherlands
Tauranga Hospital, Tauranga, BAY OF Plenty, New Zealand
Auckland City Hospital, Auckland, , New Zealand
Auckland District Health Board Charitable Trust, Auckland, , New Zealand
Haukeland University Hospital, Bergen, Hordaland, Norway
Stavanger Universitetssykehus, Stavanger, Rogaland, Norway
St. Olavs hospital, Trondheim, Sør-trøndelag, Norway
Sørlandet Sykehus Kristiansand, Kristiansand, Vest-agder, Norway
Oslo universitetssykehus, Radiumhospitalet, Oslo, , Norway
Oslo Universitetssykehus Ullevål, Oslo, , Norway
Przychodnia Lekarska KOMED, Konin, Wielkopolskie, Poland
Szpital Specjalistyczny W Brzozowie, Podkarpacki Osrodek Onkologiczny Im.Ks.B.Markiewicza, Brzozow, , Poland
Wojewodzki Szpital Specjalistyczny Nr 4 w Bytomiu Oddzial Onkologii, Bytom, , Poland
COPERNICUS PL sp. z. o. o. Wojewodzkie Centrum Onkologii w Gdansku Ambulatoryjna, Gdansk, , Poland
COPERNICUS Podmiot Leczniczy Sp. z o.o. Wojewodzkie Centrum Onkologii, Gdansk, , Poland
Przychodnia Lekarska KOMED, Konin, , Poland
Private Medical Institution "Euromedservice", Pushkin, Saint-petersburg, Russian Federation
Private Medical Institution "Euromedservice", Pushkin, Sankt-peterburg, Russian Federation
GBUZ, Chelyabinsk, , Russian Federation
Kaluga Regional Clinical Oncology Center, Kaluga, , Russian Federation
FSAEI HE I.M Sechenov First MSMU MoH Russia (Sechenovskiy University),, Moscow, , Russian Federation
BHI of Omsk Region "Clinical Oncology Dispensary", Omsk, , Russian Federation
BHI of Omsk Region "Clinical Oncology Dispensary", Omsk, , Russian Federation
LLC "EuroCityClinic", Saint Petersburg, , Russian Federation
LLC "Medicina Severnoy Stolitsy", Saint-Petersburg, , Russian Federation
LLC "Severo-Zapadny Medical Center", Saint-Petersburg, , Russian Federation
Private Healthcare Institution "Clinical Hospital "RZD-Medicine" of St. Petersburg, Saint-Petersburg, , Russian Federation
FSBI "Russian Scientific Center For Radiology and Surgical Technologies n.a. Academician A.M. Granov, St. Petersburg, , Russian Federation
SHI YR Regional Clinical Oncology Hospital, Yaroslavl, , Russian Federation
SHI YR Regional Clinical Oncology Hospital, Yaroslavl, , Russian Federation
SHI YR Regional Clinical Oncology Hospital, Yaroslav, , Russian Federation
Fakultna nemocnica s poliklinikou F. D. Roosevelta Banska Bystrica, Banska Bystrica, , Slovakia
Fakultna nemocnica s poliklinikou F. D. Roosevelta Banska Bystrica, Banska Bystrica, , Slovakia
Onkologicky ustav sv. Alzbety s.r.o., Bratislava, , Slovakia
Narodny Onkologicky Ustav, Bratislava, , Slovakia
Vychodoslovensky onkologicky ustav, a.s., Kosice, , Slovakia
POKO Poprad s.r.o., Poprad, , Slovakia
Cancercare Rondebosch Oncology, Rondebosch, Cape Town, South Africa
Cancercare Langenhoven Drive Oncology Centre, Port Elizabeth, Eastern CAPE, South Africa
Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng, South Africa
Wits Clinical Research, Parktown, Johannesburg, Gauteng, South Africa
Cape Town Oncology Trials, Cape Town, Western CAPE, South Africa
Wits Health Consortium (Pty) Ltd, Johannesburg, , South Africa
Mary Potter Oncology Centre, Pretoria, , South Africa
Complejo Hospitalario Universitario Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
Hospital General Universitario de Elche, Elche, Alicante, Spain
ICO L'Hospitalet (Hospital Duran i Reynals), Hospitalet de Llobregat, Barcelona, Spain
Hospital Universitario Vall d'Hebron, Barcelona, , Spain
Hospital Clinic Barcelona, Barcelona, , Spain
Hospital General Universitario Gregorio Marañon, Madrid, , Spain
Hospital Universitario Ramon Y Cajal, Madrid, , Spain
Hospital Universitario 12 de octubre, Madrid, , Spain
Hospital Universitario Virgen Del Rocio, Sevilla, , Spain
Hospital Clinico Universitario de Valencia, Valencia, , Spain
Hospital General Universitario de Valencia, Valencia, , Spain
Hospital Universitario Miguel Servet, Zaragoza, , Spain
Karolinska Universitetssjukhuset Solna, Solna, Stockholms LÄN [se-01], Sweden
Akademiska sjukhuset, Uppsala, Uppsala LÄN [se-03], Sweden
Norrlands universitetssjukhus, Umeå, Västerbottens LÄN [se-24], Sweden
Sahlgrenska Universitetssjukhuset, Göteborg, Västra Götalands LÄN [se14], Sweden
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
National Cheng-Kung University Hospital, Tainan, , Taiwan
Chi Mei Hospital, Liouying, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Medical University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Chang Gung Medical Foundation-Linkou Branch, Taoyuan, , Taiwan
Medical and diagnostic center of MediX-Ray International Group LLC Israeli Oncology Hospital "LISOD", Pliuty Village, KYIV Region, Obuhovskiy District, Ukraine
Municipal Non-profit Enterprise "City Clinical Hospital #4" of Dnipro City Council, Dnipro, , Ukraine
PRECARPATHIAN NUCLEAR MEDICINE CENTER, Limited Liability Company, Ivano-Frankivsk, , Ukraine
Ivano-Frankivsk National Medical University, Ivano-Frankivsk, , Ukraine
MNPE "Prykarpatski Clinical Oncological Center" of Ivano-Frankivsk Regional Council", Ivano-Frankivsk, , Ukraine
Municipal non-profit enterprise "City clinical hospital #2 named after O.O.Shalimov", Kharkiv, , Ukraine
Communal Non-Profit Enterprise "Regional Center of Oncology", Kharkiv, , Ukraine
Communal enterprise "Kryvyi Rih Oncology Dispensary" of Dnipropetrovsk Regional Council, Kryvyi Rih, , Ukraine
SI "Insitute of Neurosurgery n.a.acad. A.P., Kyiv, , Ukraine
SI "Insitute of Neurosurgery n.a.acad. A.P., Kyiv, , Ukraine
Municipal non-profit enterprise of Kyiv regional council "Kyiv regional clinical hospital", Kyiv, , Ukraine
Municipal non-profit enterprise "Zaporizhzhia Regional Antitumor Center" Zaporizhzhia Regional, Zaporizhzhia, , Ukraine
Freeman Hospital, Newcastle upon Tyne, HIGH Heaton, United Kingdom
Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
Heartlands Hospital, Birmingham, , United Kingdom
Royal Marsden NHS Foundation Trust, London, , United Kingdom
Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, , United Kingdom
Hammersmith Hospital, London, , United Kingdom
Churchill Hospital - Oncology, Oxford, , United Kingdom
Contact Details
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR
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