Spots Global Cancer Trial Database for rectal diseases
Every month we try and update this database with for rectal diseases cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Drainage After Rectal Excision for Rectal Cancer | NCT01269567 | Rectal Cancer S... Randomized Clin... Multicenter Stu... Pelvic Drainage | Laying and mana... No pelvic drain... | 18 Years - | University Hospital, Bordeaux | |
| Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases | NCT05322486 | Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Neoplasms Neoplasms, Seco... Neoplasm Metast... Digestive Syste... Gastrointestina... Colonic Disease Intestinal Dise... Rectal Diseases | surgery of the ... chemotherapy | 18 Years - | State Scientific Centre of Coloproctology, Russian Federation | |
| Multi-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development Studies | NCT01260168 | Colorectal Neop... Digestive Syste... Colonic Disease... Colorectal Canc... | 40 Years - 90 Years | Exact Sciences Corporation | ||
| Prevention of Colorectal Cancer Through Multiomics Blood Testing | NCT04369053 | Colon Cancer Rectal Cancer Colon Neoplasm Colon Diseases Colon Lesion Colon Polyp Colorectal Canc... Polyp Adenoma Rectal Diseases Gastrointestina... | Freenome test | 45 Years - 85 Years | Freenome Holdings Inc. | |
| Multi-Target Colorectal Cancer Screening Test for the Detection of Colorectal Advanced Adenomatous Polyps and Cancer | NCT01397747 | Colorectal Neop... Digestive Syste... Colonic Disease... Colorectal Canc... | 50 Years - 84 Years | Exact Sciences Corporation | ||
| Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial | NCT01995942 | Adenocarcinoma Rectal Diseases Colorectal Neop... Adenocarcinoma,... Carcinoma Neoplasms, Glan... Neoplasms by Hi... Neoplasms Neoplasms, Cyst... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Digestive Syste... Gastrointestina... Intestinal Dise... | 18 Years - | Royal Marsden NHS Foundation Trust | ||
| An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer | NCT01397305 | Rectal Cancer | [6R] 5,10-methy... Pemetrexed | 18 Years - | Isofol Medical AB | |
| SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC) | NCT01966289 | Metastatic Colo... | CY GVAX SGI-110 | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC) | NCT01966289 | Metastatic Colo... | CY GVAX SGI-110 | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Microbiome Test for the Detection of Colorectal Polyps and Cancer | NCT02141945 | Colorectal Neop... Colorectal Canc... | 45 Years - 80 Years | Metabiomics Corp | ||
| Low Rectal Cancer Study (MERCURY II) | NCT02005965 | Adenocarcinoma Adenocarcinoma,... Carcinoma Neoplasms, Glan... Neoplasms by Hi... Neoplasms Neoplasms, Cyst... Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Digestive Syste... Gastrointestina... Intestinal Dise... Rectal Diseases | 18 Years - | Royal Marsden NHS Foundation Trust | ||
| BowelScope: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities | NCT03072472 | Colorectal Neop... Colonic Polyp Adenoma Neoplasia GI Digestive Syste... Intestinal Neop... Neoplasms, Glan... Digestive Disea... Intestinal Dise... Colonic Disease... Rectal Diseases Intestinal Poly... Polyps Pathological Co... | Endocuff Vision | 55 Years - 61 Years | South Tyneside and Sunderland NHS Foundation Trust | |
| Stool Sample Collection Protocol for Development of Screening Test for Colorectal Cancer and Other Digestive Tract Cancers | NCT02503631 | Colorectal Neop... Digestive Syste... Colonic Disease... Colorectal Canc... | Stool Sample Co... | 40 Years - 90 Years | Exact Sciences Corporation | |
| Drainage After Rectal Excision for Rectal Cancer | NCT01269567 | Rectal Cancer S... Randomized Clin... Multicenter Stu... Pelvic Drainage | Laying and mana... No pelvic drain... | 18 Years - | University Hospital, Bordeaux | |
| Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases | NCT05322486 | Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Neoplasms Neoplasms, Seco... Neoplasm Metast... Digestive Syste... Gastrointestina... Colonic Disease Intestinal Dise... Rectal Diseases | surgery of the ... chemotherapy | 18 Years - | State Scientific Centre of Coloproctology, Russian Federation | |
| Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type mCRC Patients | NCT04080843 | Colorectal Canc... RAS and BRAF Wi... Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Neoplasms Digestive Syste... Gastrointestina... Colonic Disease... Intestinal Dise... Rectal Diseases | Anlotinib Hydro... Capecitabine Oxaliplatin | 18 Years - 75 Years | Zhejiang University | |
| Drainage After Rectal Excision for Rectal Cancer | NCT01269567 | Rectal Cancer S... Randomized Clin... Multicenter Stu... Pelvic Drainage | Laying and mana... No pelvic drain... | 18 Years - | University Hospital, Bordeaux | |
| Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer | NCT01294826 | Recurrent Colon... Recurrent Recta... Stage IV Colon ... Stage IV Rectal... Adenocarcinoma ... Adenocarcinoma ... | AUY922 Cetuximab | 18 Years - | Swedish Medical Center | |
| A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node Metastasis | NCT06048146 | Lymph Node Meta... Cancer of Rectu... Oxaliplatin Intestinal Neop... Gastrointestina... Rectal Diseases Rectal Neoplasm... | Experimental: F... Preoperative lo... | 18 Years - 70 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Intra-arterial Y-90 TheraSpheres for Hepatic Metastases From Solid Tumors | NCT01177007 | Liver Neoplasms | TheraSphere, Yt... | 18 Years - | Yale University | |
| Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer | NCT00838578 | Colorectal Canc... | KRN330 Irinotecan | 18 Years - | Kyowa Kirin Co., Ltd. | |
| Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer | NCT03633539 | Colorectal Canc... Colonic Neoplas... Rectal Neoplasm... Colon Disease Colon Cancer Rectal Cancer Rectal Diseases | Single-incision... Conventional La... | 18 Years - 85 Years | Ruijin Hospital | |
| ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial | NCT04084249 | Colorectal Canc... Colo-rectal Can... ctDNA Gastro-Intestin... Colorectal Neop... Gastrointestina... Gastrointestina... Digestive Syste... Digestive Syste... Colonic Disease... Colonic Neoplas... Colonic Cancer Rectal Diseases Rectal Neoplasm... Rectal Cancer | ctDNA-analysis Intensified Fol... | 18 Years - | University of Aarhus | |
| Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal Adenocarcinoma | NCT03559543 | Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Rectal Diseases Colonic Disease... Intestinal Dise... Gastrointestina... Digestive Syste... | Ocoxin-Viusid | 18 Years - | Catalysis SL | |
| Study of PRoliferation and Apoptosis in Rectal Cancer, Predictive & Prognostic biOmarkers: Histopathology and Imaging | NCT02486094 | Neoplasms Colorectal Neop... Rectal Diseases Gastrointestina... | 18 Years - | Royal Marsden NHS Foundation Trust | ||
| Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | NCT01550510 | Stage IV Colore... | Ascorbic Acid Irinotecan | 18 Years - | Thomas Jefferson University | |
| Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer | NCT03633539 | Colorectal Canc... Colonic Neoplas... Rectal Neoplasm... Colon Disease Colon Cancer Rectal Cancer Rectal Diseases | Single-incision... Conventional La... | 18 Years - 85 Years | Ruijin Hospital | |
| CRC Detection Reliable Assessment With Blood | NCT05551052 | Colorectal Canc... Adenomas Colon Colon Cancer Rectal Cancer Colon Neoplasm Colon Lesion Colon Disease Colon Polyp Polyps Adenoma Rectal Diseases Rectal Polyp Gastrointestina... Intestinal Neop... Colonic Disease... Intestinal Dise... | Next-Gen CRC Sc... | 45 Years - | Epigenomics, Inc | |
| A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer | NCT04607421 | Neoplasms | Encorafenib Cetuximab Oxaliplatin Irinotecan Leucovorin 5-FU Capecitabine Bevacizumab | 16 Years - | Pfizer | |
| The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin | NCT01549418 | Gastrointestina... | Aspirin (ASA) Placebo | 40 Years - | Maria Sklodowska-Curie National Research Institute of Oncology | |
| A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node Metastasis | NCT06048146 | Lymph Node Meta... Cancer of Rectu... Oxaliplatin Intestinal Neop... Gastrointestina... Rectal Diseases Rectal Neoplasm... | Experimental: F... Preoperative lo... | 18 Years - 70 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery | NCT00487409 | Colonic Disease... Rectal Diseases | Bipolar electro... Disposable stap... | 18 Years - 80 Years | University Hospitals Cleveland Medical Center | |
| Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal Adenocarcinoma | NCT03559543 | Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Rectal Diseases Colonic Disease... Intestinal Dise... Gastrointestina... Digestive Syste... | Ocoxin-Viusid | 18 Years - | Catalysis SL | |
| Low Rectal Cancer Study (MERCURY II) | NCT02005965 | Adenocarcinoma Adenocarcinoma,... Carcinoma Neoplasms, Glan... Neoplasms by Hi... Neoplasms Neoplasms, Cyst... Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Digestive Syste... Gastrointestina... Intestinal Dise... Rectal Diseases | 18 Years - | Royal Marsden NHS Foundation Trust | ||
| Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer | NCT01294826 | Recurrent Colon... Recurrent Recta... Stage IV Colon ... Stage IV Rectal... Adenocarcinoma ... Adenocarcinoma ... | AUY922 Cetuximab | 18 Years - | Swedish Medical Center | |
| Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing | NCT01600209 | Colorectal Neop... Digestive Syste... Colonic Disease... Colorectal Canc... | 50 Years - 84 Years | Exact Sciences Corporation | ||
| Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness | NCT01816607 | Rectal Diseases Rectal Neoplasm... Gastrointestina... Gastrointestina... | new functional ... | 18 Years - | University Hospital, Akershus | |
| Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type mCRC Patients | NCT04080843 | Colorectal Canc... RAS and BRAF Wi... Colorectal Neop... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Neoplasms Digestive Syste... Gastrointestina... Colonic Disease... Intestinal Dise... Rectal Diseases | Anlotinib Hydro... Capecitabine Oxaliplatin | 18 Years - 75 Years | Zhejiang University | |
| Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer | NCT01294826 | Recurrent Colon... Recurrent Recta... Stage IV Colon ... Stage IV Rectal... Adenocarcinoma ... Adenocarcinoma ... | AUY922 Cetuximab | 18 Years - | Swedish Medical Center | |
| ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial | NCT04084249 | Colorectal Canc... Colo-rectal Can... ctDNA Gastro-Intestin... Colorectal Neop... Gastrointestina... Gastrointestina... Digestive Syste... Digestive Syste... Colonic Disease... Colonic Neoplas... Colonic Cancer Rectal Diseases Rectal Neoplasm... Rectal Cancer | ctDNA-analysis Intensified Fol... | 18 Years - | University of Aarhus | |
| A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer | NCT02753127 | Colorectal Canc... | Napabucasin Fluorouracil Leucovorin Irinotecan Bevacizumab | 18 Years - | Sumitomo Pharma America, Inc. | |
| Sample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD) | NCT02503696 | Inflammatory Bo... Colorectal Neop... Digestive Syste... Colonic Disease... Colorectal Canc... | Stool Collectio... | 18 Years - 84 Years | Exact Sciences Corporation | |
| Sample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD) | NCT02503696 | Inflammatory Bo... Colorectal Neop... Digestive Syste... Colonic Disease... Colorectal Canc... | Stool Collectio... | 18 Years - 84 Years | Exact Sciences Corporation | |
| Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | NCT01550510 | Stage IV Colore... | Ascorbic Acid Irinotecan | 18 Years - | Thomas Jefferson University | |
| A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node Metastasis | NCT06048146 | Lymph Node Meta... Cancer of Rectu... Oxaliplatin Intestinal Neop... Gastrointestina... Rectal Diseases Rectal Neoplasm... | Experimental: F... Preoperative lo... | 18 Years - 70 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
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