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Brief Title: Cox-2 Inhibition in Radiation-induced Oral Mucositis
Official Title: Cyclooxygenase-2 Inhibition in Radiation-Induced Oral Mucositis
Study ID: NCT00698204
Brief Summary: Oral mucositis refers to ulcerative lesions of the oral mucosa that occur due to radiation therapy given for treatment of head and neck cancer. These lesions are painful, compromise nutrition and quality of life and may necessitate interruptions in radiation therapy, thus adversely affecting cancer therapy outcomes. This study examined the use of an anti-inflammatory medicine to reduce pain and severity of oral mucositis.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Connecticut Health Center, Farmington, Connecticut, United States
Hartford Hospital, Hartford, Connecticut, United States
Name: Rajesh V Lalla, DDS, Ph.D, CCRP
Affiliation: UConn Health
Role: PRINCIPAL_INVESTIGATOR