Spots Global Cancer Trial Database for The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan

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Trial Identification

Brief Title: The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan

Official Title: The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan

Study ID: NCT05522881

Conditions

Oropharyngeal Squamous Cell Carcinoma

Interventions

Study Description

Brief Summary: We will use the next-generation sequencing (NGS) technology to identify genomic alterations of Taiwanese HPV positive and negative oropharyngeal squamous cell carcinoma (OPSCC) for novel biomarker development and the study design of potential clinical trials or translational research.

Detailed Description: In the past decade, next-generation sequencing (NGS) technology has enabled cancer genome sequencing in screening and searching for new cancer genes in an efficient manner. This massive sequencing technique not only help to identify new altered genes for novel biomarker development, but also reveal gene alterations sensitive or resistant to specific therapies. Because the difference of genomic profiling between Taiwanese HPV positive and negative OPSCC is not clear yet, we propose this multi-center research project to address this issue. In this study, we will collect tumor tissues and clinical information from patients with OPSCC and create a platform for data storage and sharing.