Spots Global Cancer Trial Database for precision medicine
Every month we try and update this database with for precision medicine cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Hyperpolarized 13C MRI for Cancer Immunotherapy | NCT05805358 | Gynecologic Can... Cervical Cancer Endometrial Can... Ovarian Cancer | Hyperpolarized ... | 20 Years - | Chang Gung Memorial Hospital | |
| SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry | NCT03452774 | Cancer, Metasta... Cancer Cancer of Pancr... Cancer of Liver Cancer of Stoma... Cancer Liver Cancer of Rectu... Cancer of Kidne... Cancer of Esoph... Cancer of Cervi... Cancer of Colon Cancer of Laryn... Cancer, Lung Cancer, Breast Cancer, Advance... Cancer Prostate Cancer of Neck Cancer of Skin Neuroendocrine ... Carcinoma Mismatch Repair... BRCA Gene Rearr... Non Hodgkin Lym... Leukemia Non Small Cell ... Cholangiocarcin... Glioblastoma Central Nervous... Melanoma Urothelial Carc... Bladder Cancer Ovarian Cancer Endometrial Can... Testicular Canc... Breast Cancer COVID Myelofibrosis Myeloproliferat... Myeloproliferat... Follicular Lymp... Mantle Cell Lym... Marginal Zone L... Myelodysplastic... | Clinical Trial ... | - | Massive Bio, Inc. | |
| Personalized Oncogenomics (POG) Program of British Columbia | NCT02155621 | Metastatic Canc... Advanced Cancer... Cancers That Ca... | Genome sequenci... | 18 Years - 85 Years | British Columbia Cancer Agency | |
| PRecISion Medicine for Children With Cancer | NCT03336931 | Childhood Cance... Childhood Solid... Childhood Brain... Childhood Leuke... Refractory Canc... Relapsed Cancer | Molecular profi... | - 21 Years | Sydney Children's Hospitals Network | |
| Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation | NCT04727827 | Hematopoietic C... Oncology | Pharmacogenomic... | 18 Years - | Wake Forest University Health Sciences | |
| Hyperpolarized 13C MRI for Cancer Immunotherapy | NCT05805358 | Gynecologic Can... Cervical Cancer Endometrial Can... Ovarian Cancer | Hyperpolarized ... | 20 Years - | Chang Gung Memorial Hospital | |
| Feasibility of Individualized Therapy for Recurrent Glioblastoma | NCT03681028 | Recurrent Gliob... | Individualized ... | 18 Years - | University of California, San Francisco | |
| BostonGene-Integrated Genomic Registry (BIGR) | NCT04991922 | Malignancy | 18 Years - | BostonGene | ||
| Precision Medicine for Every Child With Cancer | NCT05504772 | Childhood Cance... Childhood Solid... Childhood Brain... Childhood Leuke... Refractory Canc... Relapsed Cancer | Whole Genome Se... RNA seq DNA Methylation Targeted Panel ... High Throughput... Patient Derived... Liquid Biopsy | 0 Years - 25 Years | Australian & New Zealand Children's Haematology/Oncology Group | |
| Early Detection of Hepatocellular Carcinoma in a High-risk Prospective Cohort (ELEGANCE) | NCT04965259 | Liver Diseases | 40 Years - 90 Years | National Cancer Centre, Singapore | ||
| Achieving Equity in Genomic Testing for Breast Cancer Through Partner-Led Strategies and Policies | NCT05916378 | Breast Cancer | 18 Years - 99 Years | Stanford University | ||
| Personalised Disease Monitoring in Metastatic Breast Cancer | NCT04597580 | Breast Cancer M... Estrogen Recept... | 18 Years - | The Christie NHS Foundation Trust | ||
| The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan | NCT05522881 | Oropharyngeal S... | 20 Years - | National Health Research Institutes, Taiwan | ||
| Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations | NCT04906031 | Myelodysplastic... Acute Myeloid L... Myeloid Maligna... Temperature-Sen... Sodium Stiboglu... P53 Mutation | Sodium stiboglu... | 18 Years - 75 Years | First Affiliated Hospital of Jinan University | |
| PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas | NCT05473923 | Recurrent High ... | Receiving chemo... | 18 Years - 75 Years | Beijing Tiantan Hospital | |
| Breast Cancer, Omics, and Precision Medicine | NCT04996836 | Breast Cancer | Next Generation... | 18 Years - | University of Campania "Luigi Vanvitelli" | |
| Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients | NCT04340024 | Nasopharyngeal ... Prostate Cancer Other Cancer | 21 Years - 99 Years | National Cancer Centre, Singapore | ||
| Decision Support for BRCA Testing in Ethnically Diverse Women | NCT03470402 | Breast Cancer BRCA1 Mutation BRCA2 Mutation Ovarian Cancer | RealRisks BNAV iNYP Standard Educat... High-Risk Messa... | 21 Years - 75 Years | Columbia University | |
| A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy | NCT05630989 | Pancreatic Duct... | combination the... combination the... combination the... combination the... | 18 Years - | Medical College of Wisconsin | |
| A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC) | NCT06163534 | Head and Neck S... | 18 Years - | Tempus AI | ||
| Ensuring Precision-Medicine Delivery for Veterans With Lung Cancer | NCT05795959 | Lung Cancer | Receive educati... | 18 Years - | Stanford University | |
| Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy | NCT06375915 | Intrahepatic Ch... | radioembolizati... Durvalumab Cisplatin Gemcitabine | 18 Years - 80 Years | IRCCS San Raffaele | |
| A Taiwanese Oncogenetic Panel and Integrated Clinical Data Registry Study for Diffuse Glioma | NCT05622409 | Primary Maligna... | A Taiwanese Onc... | 20 Years - | National Health Research Institutes, Taiwan | |
| TCF-001 TRACK (Target Rare Cancer Knowledge) Study | NCT04504604 | Rare Cancers Cholangiocarcin... Cancer of Unkno... | FoundationOne C... | 18 Years - | TargetCancer Foundation | |
| Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors | NCT04683939 | Solid Tumor Gastric Cancer Gastroesophagea... Esophageal Aden... Pancreatic Canc... Biliary Tract C... Cholangiocarcin... Metastatic Canc... | BNT141 Nab-paclitaxel Gemcitabine | 18 Years - | BioNTech SE | |
| A Retrospective Pharmacokinetics and Pharmacogenomics Research of Imatinib in Gastrointestinal Stromal Tumor Treatment | NCT03092128 | Gastrointestina... Germline Mutati... Somatic Mutatio... Plasma Concentr... | 18 Years - 80 Years | Sun Yat-sen University | ||
| The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan | NCT05522881 | Oropharyngeal S... | 20 Years - | National Health Research Institutes, Taiwan | ||
| A Retrospective Pharmacokinetics and Pharmacogenomics Research of Imatinib in Gastrointestinal Stromal Tumor Treatment | NCT03092128 | Gastrointestina... Germline Mutati... Somatic Mutatio... Plasma Concentr... | 18 Years - 80 Years | Sun Yat-sen University | ||
| Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO) | NCT06038760 | Brain Tumor Glioma, Maligna... Ependymoma Oligodendroglio... Glioblastoma | Resection | 18 Years - | Ourotech, Inc. | |
| Community Health Workers and Precision Medicine | NCT04843332 | Cancer Tumor | Community Healt... | 18 Years - | Stanford University | |
| Cardio-Oncology Registry | NCT04407780 | Cancer Cardiac Disease Metabolic Syndr... Arrhythmia Heart Diseases | No intervention... | 18 Years - | European Georges Pompidou Hospital | |
| Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy | NCT06375915 | Intrahepatic Ch... | radioembolizati... Durvalumab Cisplatin Gemcitabine | 18 Years - 80 Years | IRCCS San Raffaele | |
| Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care | NCT04141397 | Metastatic Canc... Advanced Cancer Cancers That Ca... | Initiation of P... Usual care | 19 Years - 85 Years | British Columbia Cancer Agency | |
| Breast Cancer, Omics, and Precision Medicine | NCT04996836 | Breast Cancer | Next Generation... | 18 Years - | University of Campania "Luigi Vanvitelli" | |
| Estrogen Receptor-Positive Breast Cancer Patient-Derived Xenografts | NCT02752893 | Breast Cancer | 18 Years - | Dartmouth-Hitchcock Medical Center | ||
| Dissection of the Molecular and Immunological Interaction in Patients With HCC of Viral and Non-viral Etiologies | NCT05613621 | Hepatocellular ... | 20 Years - | National Health Research Institutes, Taiwan | ||
| TCF-001 TRACK (Target Rare Cancer Knowledge) Study | NCT04504604 | Rare Cancers Cholangiocarcin... Cancer of Unkno... | FoundationOne C... | 18 Years - | TargetCancer Foundation | |
| Personalised Disease Monitoring in Metastatic Breast Cancer | NCT04597580 | Breast Cancer M... Estrogen Recept... | 18 Years - | The Christie NHS Foundation Trust | ||
| DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. | NCT05768178 | Solid Tumor Haematological ... Melanoma Thyroid Cancer,... Ovarian Neoplas... Colorectal Neop... Laryngeal Neopl... Carcinoma, Non-... Glioma Multiple Myelom... Erdheim-Chester... Thyroid Carcino... | Vemurafenib Cobimetinib | 18 Years - | Cancer Research UK | |
| Precision Medicine for Combined Hepatocellular-Cholangiocarcinoma | NCT06146127 | Liver Cancer | phenotyping | 18 Years - | Inserm U955 | |
| Estrogen Receptor-Positive Breast Cancer Patient-Derived Xenografts | NCT02752893 | Breast Cancer | 18 Years - | Dartmouth-Hitchcock Medical Center | ||
| Liver Cancer and Immunotherapy in the Liquid Biopsy Era | NCT05810402 | Hepatocellular ... BCLC Stage B He... BCLC Stage C He... Immune Checkpoi... Liquid Biopsy | Liquid Biopsy | 18 Years - | University Hospital, Montpellier | |
| TCF-001 TRACK (Target Rare Cancer Knowledge) Study | NCT04504604 | Rare Cancers Cholangiocarcin... Cancer of Unkno... | FoundationOne C... | 18 Years - | TargetCancer Foundation | |
| RNA Precision Oncology in Advanced Pancreatic Cancer | NCT04476537 | Pancreatic Canc... | OncoTreat | 18 Years - | Columbia University | |
| A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy | NCT05630989 | Pancreatic Duct... | combination the... combination the... combination the... combination the... | 18 Years - | Medical College of Wisconsin | |
| Precision Medicine for Every Child With Cancer | NCT05504772 | Childhood Cance... Childhood Solid... Childhood Brain... Childhood Leuke... Refractory Canc... Relapsed Cancer | Whole Genome Se... RNA seq DNA Methylation Targeted Panel ... High Throughput... Patient Derived... Liquid Biopsy | 0 Years - 25 Years | Australian & New Zealand Children's Haematology/Oncology Group | |
| Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients | NCT06090513 | Advanced Cancer Solid Tumor, Ad... Myeloid Maligna... | Comprehensive G... limited genetic... | 18 Years - | Bien-Willner Physicians Group PA | |
| Organoid-based Functional Precision Therapy for Advanced Breast Cancer | NCT06102824 | HER2-negative B... Advanced Breast... | Organoid-guided... Taxane Capecitabine Gemcitabine Vinorelbine Eribulin Anthracycline Carboplatin Utidelone Trastuzumab der... Sacituzumab gov... | 18 Years - 80 Years | Guangdong Provincial People's Hospital | |
| Organoid-based Functional Precision Therapy for Advanced Breast Cancer | NCT06102824 | HER2-negative B... Advanced Breast... | Organoid-guided... Taxane Capecitabine Gemcitabine Vinorelbine Eribulin Anthracycline Carboplatin Utidelone Trastuzumab der... Sacituzumab gov... | 18 Years - 80 Years | Guangdong Provincial People's Hospital | |
| Proseq Cancer: Genomic Profiling in Patients With Incurable Cancer in Search for Targeted Treatment | NCT05695638 | Solid Tumor, Un... Haematological ... | 18 Years - | Aalborg University Hospital | ||
| A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy | NCT05630989 | Pancreatic Duct... | combination the... combination the... combination the... combination the... | 18 Years - | Medical College of Wisconsin | |
| Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care | NCT04141397 | Metastatic Canc... Advanced Cancer Cancers That Ca... | Initiation of P... Usual care | 19 Years - 85 Years | British Columbia Cancer Agency | |
| Functional Precision Oncology for Metastatic Breast Cancer | NCT04450706 | HER2-negative B... | Precision Medic... Physican Decisi... | 18 Years - | University of Utah | |
| Prospective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma | NCT03267641 | Hepatocellular ... | 21 Years - 80 Years | National Cancer Centre, Singapore | ||
| The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan | NCT05522881 | Oropharyngeal S... | 20 Years - | National Health Research Institutes, Taiwan | ||
| A MolEcularly Guided Anti-Cancer Drug Off-Label Trial | NCT04185831 | Solid Tumor | Atezolizumab Everolimus Cobimetinib | 18 Years - | Uppsala University Hospital | |
| Organoid-based Functional Precision Therapy for Advanced Breast Cancer | NCT06102824 | HER2-negative B... Advanced Breast... | Organoid-guided... Taxane Capecitabine Gemcitabine Vinorelbine Eribulin Anthracycline Carboplatin Utidelone Trastuzumab der... Sacituzumab gov... | 18 Years - 80 Years | Guangdong Provincial People's Hospital | |
| MyCustom:Prospective Master Protocol Trial on Precision Medicine Treatment for Refractory Solid Tumors | NCT06030869 | Refractory Soli... Next Generation... | 18 Years - | Tianjin Medical University Second Hospital | ||
| BostonGene-Integrated Genomic Registry (BIGR) | NCT04991922 | Malignancy | 18 Years - | BostonGene | ||
| Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays | NCT05234177 | Colorectal Canc... | Observation | 18 Years - | Tempus AI | |
| Feasibility of Individualized Therapy for Recurrent Glioblastoma | NCT03681028 | Recurrent Gliob... | Individualized ... | 18 Years - | University of California, San Francisco | |
| Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational Study | NCT05257551 | Small Cell Lung... | Observation | 18 Years - | Tempus AI | |
| TCF-001 TRACK (Target Rare Cancer Knowledge) Study | NCT04504604 | Rare Cancers Cholangiocarcin... Cancer of Unkno... | FoundationOne C... | 18 Years - | TargetCancer Foundation | |
| Proseq Cancer: Genomic Profiling in Patients With Incurable Cancer in Search for Targeted Treatment | NCT05695638 | Solid Tumor, Un... Haematological ... | 18 Years - | Aalborg University Hospital | ||
| Hyperpolarized 13C Pyruvate MRI for Early Immune Evaluation in Cervical Cancer Patients at Baseline and CCRT Therapy | NCT04951921 | Cervical Cancer | Hyperpolarized ... | 20 Years - | Chang Gung Memorial Hospital | |
| Identification of Biomarker Profiles GEP-NEN Patients | NCT02838862 | Neuroendocrine ... | 12 Years - 95 Years | University Hospital Schleswig-Holstein | ||
| Early Detection of Hepatocellular Carcinoma in a High-risk Prospective Cohort (ELEGANCE) | NCT04965259 | Liver Diseases | 40 Years - 90 Years | National Cancer Centre, Singapore | ||
| Evaluating Disparities in Precision Oncology | NCT06081517 | Metastatic Canc... Advanced Cancer | Social Determin... | 18 Years - | Indiana University | |
| Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients | NCT06090513 | Advanced Cancer Solid Tumor, Ad... Myeloid Maligna... | Comprehensive G... limited genetic... | 18 Years - | Bien-Willner Physicians Group PA | |
| Proseq Cancer: Genomic Profiling in Patients With Incurable Cancer in Search for Targeted Treatment | NCT05695638 | Solid Tumor, Un... Haematological ... | 18 Years - | Aalborg University Hospital |
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