Spots Global Cancer Trial Database for Polycystic Ovary Syndrome (PCOS) - Effect Of Physical Exercise And Electroacupuncture

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Trial Identification

Brief Title: Polycystic Ovary Syndrome (PCOS) - Effect Of Physical Exercise And Electroacupuncture

Official Title: Polycystic Ovary Syndrome (PCOS) - The Female Metabolic Syndrome Genes And Processes In The Aetiology And Pathogenesis Of PCOS And Identification Of New Treatment Strategies

Study ID: NCT00484705

Conditions

Polycystic Ovary Syndrome

Interventions

Electroacupuncture

Physical exercise

Untreated control

Study Description

Brief Summary: Hypothesis: The overall hypothesis is that women with PCOS, both obese and non-obese, have larger adipocytes, altered metabolism and signs of inflammation in adipose tissue and that these changes are associated with high sympathetic nerve activity, hyperandrogenism hyperinsulinaemia, insulin resistance with progression to type II diabetes and cardiovascular disease (CVD) as well as psychological distress and reduced quality of life. Physical exercise and electro-acupuncture decrease high concentrations of androgens, induce regulare menstrual pattern, inhibits high sympathetic activity and restore the PCOS induced disturbances.

Detailed Description: Primary outcome: Changes in androgen concentrations and menstrual pattern Secondary outcome: changes in sympathetic nerve activity, uterus peristalsis, ovarian morphology, adipose tissue related variables, insulin sensitivity, coagulation factors and health related quality of life and symptoms of anxiety and depression.