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Spots Global Cancer Trial Database for Diagnosis; Objective RespOnse; THErApy

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Diagnosis; Objective RespOnse; THErApy

Official Title: Mutational Analysis in the Cerebrospinal Fluid to Improve Diagnostic Sensitivity, Response Definition and Precision Treatment in Primary Central Nervous System Lymphoma

Study ID: NCT05036564

Interventions

Lumbar puncture

Study Description

Brief Summary: Thi is a prospective and low-intervention clinical trial. We propose to design a panel of "core" genetic alterations by sequencing Cerebral Spinal Fluid (CSF) DNA in patients with confirmed or suspicious Primary Central Neurvous System Lymphoma (PCNSL) with the aim to improve diagnostic sensitivity, response assessment and monitoring early CNS relapse in routine practice. Enrolled patients will receive conventional treatments according to well-established international guidelines, DNA assessments will not influence the treatment choices.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

IRCCS Ospedale San Raffaele, Milan, Italy/Lombardy, Italy

Contact Details

Name: Andrés J.M. Ferreri, MD

Affiliation: IRCCS Ospedale San Raffaele

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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