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Spots Global Cancer Trial Database for lumbar puncture

Every month we try and update this database with for lumbar puncture cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)NCT06210750
T Acute Lymphob...
T Lymphoblastic...
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Calaspargase Pe...
Computed Tomogr...
Cyclophosphamid...
Cytarabine
Daunorubicin
Dexamethasone
Doxorubicin
Echocardiograph...
Lumbar Puncture
Mercaptopurine
Methotrexate
Multigated Acqu...
Navitoclax
Nelarabine
Pegaspargase
Positron Emissi...
Thioguanine
Venetoclax
Vincristine
X-Ray Imaging
18 Years - 60 YearsNational Cancer Institute (NCI)
Randomized Evaluation of a Positioning Pillow for Lumbar Puncture in Paediatric Hematology-OncologyNCT00775112
Spinal Puncture
pillow
2 Years - 18 YearsCentre Leon Berard
NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell LymphomaNCT05359211
Recurrent Diffu...
Recurrent Diffu...
Recurrent Grade...
Recurrent Prima...
Refractory Diff...
Refractory Diff...
Refractory Grad...
Refractory Prim...
Transformed Ind...
Cyclophosphamid...
Fludarabine
Lisocabtagene M...
Polymer-conjuga...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Bone Marrow Bio...
Bone Marrow Asp...
Lumbar Puncture
Computed Tomogr...
Positron Emissi...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic LeukemiaNCT02981628
Recurrent B Acu...
Recurrent B Lym...
Refractory B Ac...
Refractory B Ly...
Asparaginase Er...
Biospecimen Col...
Bone Marrow Asp...
Calaspargase Pe...
Cyclophosphamid...
Cytarabine
Diagnostic Imag...
Inotuzumab Ozog...
Leucovorin Calc...
Lumbar Puncture
Methotrexate
Pegaspargase
Vincristine
1 Year - 21 YearsChildren's Oncology Group
A Study of SNDX-5613 in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory LeukemiaNCT05761171
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Mixed...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Mixe...
Biospecimen Col...
Bone Marrow Asp...
Calaspargase Pe...
Cytarabine
Echocardiograph...
Fludarabine Pho...
Hydrocortisone ...
Lumbar Puncture
Methotrexate
Multigated Acqu...
Prednisolone
Prednisone
Revumenib
Vincristine Sul...
1 Month - 6 YearsChildren's Oncology Group
Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal DiseaseNCT03025256
Acral Lentigino...
Central Nervous...
Clinical Stage ...
Leptomeningeal ...
Melanocytoma
Metastatic Lung...
Metastatic Mela...
Metastatic Muco...
Metastatic Uvea...
Stage IV Lung C...
Biospecimen Col...
Computed Tomogr...
Lumbar Puncture
Magnetic Resona...
Nivolumab
Positron Emissi...
18 Years - M.D. Anderson Cancer Center
Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell TherapyNCT05936229
Recurrent B Acu...
Recurrent B-Cel...
Refractory B Ac...
Refractory B-Ce...
Recurrent Mantl...
Refractory Mant...
Interferon Beta...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Computed Tomogr...
Positron Emissi...
Lumbar Puncture
Bone Marrow Asp...
Bone Marrow Bio...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center
Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast CancerNCT05130840
Breast Cancer
MRI
Lumbar puncture
18 Years - Memorial Sloan Kettering Cancer Center
Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell LymphomaNCT05910801
Recurrent Mantl...
Refractory Mant...
Biopsy
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Computed Tomogr...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
Tafasitamab
Venetoclax
18 Years - Academic and Community Cancer Research United
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS LymphomaNCT04609046
Primary Diffuse...
Bone Marrow Asp...
Computed Tomogr...
Echocardiograph...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Methotrexate
Nivolumab
Positron Emissi...
Rituximab
Ultrasound Imag...
18 Years - National Cancer Institute (NCI)
Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous SystemNCT01596127
Leukemia
Lymphoid Malign...
Metastatic Mali...
Intrathecal Rit...
3 Years - M.D. Anderson Cancer Center
Co-administration of Propofol and Remifentanil for Lumbar Puncture in ChildrenNCT00405522
Spinal Puncture
Propofol 2.0 mg...
Propofol 4.0 mg...
3 Years - 12 YearsThe Hospital for Sick Children
Diagnosis; Objective RespOnse; THErApyNCT05036564
Primary CNS Lym...
Lumbar puncture
18 Years - IRCCS San Raffaele
Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute LeukemiaNCT04872790
B Acute Lymphob...
B Acute Lymphob...
Mixed Phenotype...
Recurrent B Acu...
Recurrent Mixed...
Dasatinib
Methotrexate
Prednisone
Rituximab
Venetoclax
Blinatumomab
Bone Marrow Asp...
Lumbar Puncture
Biospecimen Col...
18 Years - OHSU Knight Cancer Institute
Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell TherapyNCT04359784
B-Cell Non-Hodg...
Anakinra
X-Ray Imaging
Positron Emissi...
Computed Tomogr...
Bone Marrow Asp...
Bone Marrow Bio...
Lumbar Puncture
Biospecimen Col...
18 Years - Fred Hutchinson Cancer Center
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic LeukemiaNCT02003222
Acute Lymphobla...
B Acute Lymphob...
Allogeneic Hema...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Bone Marrow Bio...
Cyclophosphamid...
Cytarabine
Daunorubicin
Daunorubicin Hy...
Dexamethasone
Etoposide
Lumbar Puncture
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Rituximab
Vincristine
Vincristine Sul...
X-Ray Imaging
30 Years - 70 YearsNational Cancer Institute (NCI)
Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast CancerNCT05130840
Breast Cancer
MRI
Lumbar puncture
18 Years - Memorial Sloan Kettering Cancer Center
NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell LymphomaNCT05359211
Recurrent Diffu...
Recurrent Diffu...
Recurrent Grade...
Recurrent Prima...
Refractory Diff...
Refractory Diff...
Refractory Grad...
Refractory Prim...
Transformed Ind...
Cyclophosphamid...
Fludarabine
Lisocabtagene M...
Polymer-conjuga...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Bone Marrow Bio...
Bone Marrow Asp...
Lumbar Puncture
Computed Tomogr...
Positron Emissi...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast CancerNCT05746325
Anatomic Stage ...
Metastatic Brea...
Metastatic Mali...
Digital Photogr...
Lumbar Puncture
Magnetic Resona...
Medical Device ...
18 Years - Mayo Clinic
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs ControlNCT04796935
Central Nervous...
Pseudotumor Cer...
Neurological Di...
Cancer
Obstetric Proce...
Orthopedic Proc...
Post-Dural Punc...
Tactile Imaging...
Control (palpat...
18 Years - IntuiTap Medical, Inc
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic LeukemiaNCT02003222
Acute Lymphobla...
B Acute Lymphob...
Allogeneic Hema...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Bone Marrow Bio...
Cyclophosphamid...
Cytarabine
Daunorubicin
Daunorubicin Hy...
Dexamethasone
Etoposide
Lumbar Puncture
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Rituximab
Vincristine
Vincristine Sul...
X-Ray Imaging
30 Years - 70 YearsNational Cancer Institute (NCI)
Co-administration of Propofol and Remifentanil for Lumbar Puncture in ChildrenNCT00405522
Spinal Puncture
Propofol 2.0 mg...
Propofol 4.0 mg...
3 Years - 12 YearsThe Hospital for Sick Children
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS LymphomaNCT04609046
Primary Diffuse...
Bone Marrow Asp...
Computed Tomogr...
Echocardiograph...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Methotrexate
Nivolumab
Positron Emissi...
Rituximab
Ultrasound Imag...
18 Years - National Cancer Institute (NCI)
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeNCT05457556
Acute Lymphobla...
Acute Myeloid L...
Mixed Phenotype...
Myelodysplastic...
Biospecimen Col...
Bone Marrow Asp...
Busulfan
Cyclophosphamid...
Echocardiograph...
Fludarabine
Haploidentical ...
Lapine T-Lympho...
Lumbar Puncture
Matched Unrelat...
Melphalan
Methotrexate
Multigated Acqu...
Mycophenolate M...
Myeloablative C...
Quality-of-Life...
Questionnaire A...
Rituximab
T-Cell Depletio...
Tacrolimus
Thiotepa
Total-Body Irra...
6 Months - 21 YearsChildren's Oncology Group
Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced CancerNCT02580045
Metastatic Canc...
Advanced Cancer
Brain Metastasi...
18 Years - Duke University
Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in AdultsNCT04530565
B Acute Lymphob...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Cyclophosphamid...
Cytarabine
Dasatinib
Dexamethasone
Doxorubicin Hyd...
Echocardiograph...
Electrocardiogr...
Lumbar Puncture
Mesna
Methotrexate
Multigated Acqu...
Ponatinib Hydro...
Prednisone
Vincristine Sul...
18 Years - 75 YearsNational Cancer Institute (NCI)
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs ControlNCT04796935
Central Nervous...
Pseudotumor Cer...
Neurological Di...
Cancer
Obstetric Proce...
Orthopedic Proc...
Post-Dural Punc...
Tactile Imaging...
Control (palpat...
18 Years - IntuiTap Medical, Inc
Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal MetastasesNCT01713699
Meningeal Carci...
lumbar puncture
18 Years - The Netherlands Cancer Institute
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast CancerNCT05746325
Anatomic Stage ...
Metastatic Brea...
Metastatic Mali...
Digital Photogr...
Lumbar Puncture
Magnetic Resona...
Medical Device ...
18 Years - Mayo Clinic
A Study of Lower Radiotherapy Dose to Treat Children With CNS GerminomaNCT06368817
Central Nervous...
Diabetes Insipi...
Pineal Region G...
Suprasellar Ger...
3-Dimensional C...
Biospecimen Col...
Carboplatin
Etoposide
Intensity-Modul...
Lumbar Puncture
Magnetic Resona...
Questionnaire A...
Surgical Proced...
3 Years - 30 YearsChildren's Oncology Group
Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell TherapyNCT05936229
Recurrent B Acu...
Recurrent B-Cel...
Refractory B Ac...
Refractory B-Ce...
Recurrent Mantl...
Refractory Mant...
Interferon Beta...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Computed Tomogr...
Positron Emissi...
Lumbar Puncture
Bone Marrow Asp...
Bone Marrow Bio...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center
A Study of Lower Radiotherapy Dose to Treat Children With CNS GerminomaNCT06368817
Central Nervous...
Diabetes Insipi...
Pineal Region G...
Suprasellar Ger...
3-Dimensional C...
Biospecimen Col...
Carboplatin
Etoposide
Intensity-Modul...
Lumbar Puncture
Magnetic Resona...
Questionnaire A...
Surgical Proced...
3 Years - 30 YearsChildren's Oncology Group
A Study of SNDX-5613 in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory LeukemiaNCT05761171
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Mixed...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Mixe...
Biospecimen Col...
Bone Marrow Asp...
Calaspargase Pe...
Cytarabine
Echocardiograph...
Fludarabine Pho...
Hydrocortisone ...
Lumbar Puncture
Methotrexate
Multigated Acqu...
Prednisolone
Prednisone
Revumenib
Vincristine Sul...
1 Month - 6 YearsChildren's Oncology Group
Video/Audio Distraction Analgesia for Simulated Oncology Procedure PainNCT00701571
Pain
Virtual Reality...
18 Years - University of Washington
Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute LeukemiaNCT04872790
B Acute Lymphob...
B Acute Lymphob...
Mixed Phenotype...
Recurrent B Acu...
Recurrent Mixed...
Dasatinib
Methotrexate
Prednisone
Rituximab
Venetoclax
Blinatumomab
Bone Marrow Asp...
Lumbar Puncture
Biospecimen Col...
18 Years - OHSU Knight Cancer Institute
Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes) for the Treatment of Primary Central Nervous System LymphomaNCT05625594
Central Nervous...
Aspiration
Biospecimen Col...
Catheterization
CD19CAR-CD28-CD...
Computed Tomogr...
Cyclophosphamid...
Fludarabine
Leukapheresis
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
18 Years - City of Hope Medical Center
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs ControlNCT04796935
Central Nervous...
Pseudotumor Cer...
Neurological Di...
Cancer
Obstetric Proce...
Orthopedic Proc...
Post-Dural Punc...
Tactile Imaging...
Control (palpat...
18 Years - IntuiTap Medical, Inc
Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast CancerNCT02598427
HER2 Positive U...
Asymptomatic or...
Pertuzumab
Trastuzumab
18 Years - Duke University
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS LymphomaNCT04609046
Primary Diffuse...
Bone Marrow Asp...
Computed Tomogr...
Echocardiograph...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Methotrexate
Nivolumab
Positron Emissi...
Rituximab
Ultrasound Imag...
18 Years - National Cancer Institute (NCI)
Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast CancerNCT05130840
Breast Cancer
MRI
Lumbar puncture
18 Years - Memorial Sloan Kettering Cancer Center
Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell LymphomaNCT05910801
Recurrent Mantl...
Refractory Mant...
Biopsy
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Computed Tomogr...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
Tafasitamab
Venetoclax
18 Years - Academic and Community Cancer Research United
Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast CancerNCT02598427
HER2 Positive U...
Asymptomatic or...
Pertuzumab
Trastuzumab
18 Years - Duke University
Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal MetastasesNCT01713699
Meningeal Carci...
lumbar puncture
18 Years - The Netherlands Cancer Institute
Diagnosis; Objective RespOnse; THErApyNCT05036564
Primary CNS Lym...
Lumbar puncture
18 Years - IRCCS San Raffaele
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade GliomaNCT03919071
Anaplastic Astr...
Anaplastic Astr...
Anaplastic Gang...
Anaplastic Pleo...
Glioblastoma
Malignant Gliom...
WHO Grade 3 Gli...
Biospecimen Col...
Dabrafenib Mesy...
Lumbar Puncture
Magnetic Resona...
Radiation Thera...
Trametinib Dime...
12 Months - 21 YearsNational Cancer Institute (NCI)
Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell LymphomaNCT05910801
Recurrent Mantl...
Refractory Mant...
Biopsy
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Computed Tomogr...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
Tafasitamab
Venetoclax
18 Years - Academic and Community Cancer Research United
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic LeukemiaNCT02003222
Acute Lymphobla...
B Acute Lymphob...
Allogeneic Hema...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Bone Marrow Bio...
Cyclophosphamid...
Cytarabine
Daunorubicin
Daunorubicin Hy...
Dexamethasone
Etoposide
Lumbar Puncture
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Rituximab
Vincristine
Vincristine Sul...
X-Ray Imaging
30 Years - 70 YearsNational Cancer Institute (NCI)
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