Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL) NCT06210750 T Acute Lymphob...
T Lymphoblastic...
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Calaspargase Pe...
Computed Tomogr...
Cyclophosphamid...
Cytarabine
Daunorubicin
Dexamethasone
Doxorubicin
Echocardiograph...
Lumbar Puncture
Mercaptopurine
Methotrexate
Multigated Acqu...
Navitoclax
Nelarabine
Pegaspargase
Positron Emissi...
Thioguanine
Venetoclax
Vincristine
X-Ray Imaging
18 Years - 60 Years National Cancer Institute (NCI) View Randomized Evaluation of a Positioning Pillow for Lumbar Puncture in Paediatric Hematology-Oncology NCT00775112 Spinal Puncture
pillow
2 Years - 18 Years Centre Leon Berard View NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma NCT05359211 Recurrent Diffu...
Recurrent Diffu...
Recurrent Grade...
Recurrent Prima...
Refractory Diff...
Refractory Diff...
Refractory Grad...
Refractory Prim...
Transformed Ind...
Cyclophosphamid...
Fludarabine
Lisocabtagene M...
Polymer-conjuga...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Bone Marrow Bio...
Bone Marrow Asp...
Lumbar Puncture
Computed Tomogr...
Positron Emissi...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center View Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia NCT02981628 Recurrent B Acu...
Recurrent B Lym...
Refractory B Ac...
Refractory B Ly...
Asparaginase Er...
Biospecimen Col...
Bone Marrow Asp...
Calaspargase Pe...
Cyclophosphamid...
Cytarabine
Diagnostic Imag...
Inotuzumab Ozog...
Leucovorin Calc...
Lumbar Puncture
Methotrexate
Pegaspargase
Vincristine
1 Year - 21 Years Children's Oncology Group View A Study of SNDX-5613 in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia NCT05761171 Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Mixed...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Mixe...
Biospecimen Col...
Bone Marrow Asp...
Calaspargase Pe...
Cytarabine
Echocardiograph...
Fludarabine Pho...
Hydrocortisone ...
Lumbar Puncture
Methotrexate
Multigated Acqu...
Prednisolone
Prednisone
Revumenib
Vincristine Sul...
1 Month - 6 Years Children's Oncology Group View Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease NCT03025256 Acral Lentigino...
Central Nervous...
Clinical Stage ...
Leptomeningeal ...
Melanocytoma
Metastatic Lung...
Metastatic Mela...
Metastatic Muco...
Metastatic Uvea...
Stage IV Lung C...
Biospecimen Col...
Computed Tomogr...
Lumbar Puncture
Magnetic Resona...
Nivolumab
Positron Emissi...
18 Years - M.D. Anderson Cancer Center View Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell Therapy NCT05936229 Recurrent B Acu...
Recurrent B-Cel...
Refractory B Ac...
Refractory B-Ce...
Recurrent Mantl...
Refractory Mant...
Interferon Beta...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Computed Tomogr...
Positron Emissi...
Lumbar Puncture
Bone Marrow Asp...
Bone Marrow Bio...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center View Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer NCT05130840 Breast Cancer
MRI
Lumbar puncture
18 Years - Memorial Sloan Kettering Cancer Center View Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma NCT05910801 Recurrent Mantl...
Refractory Mant...
Biopsy
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Computed Tomogr...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
Tafasitamab
Venetoclax
18 Years - Academic and Community Cancer Research United View Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma NCT04609046 Primary Diffuse...
Bone Marrow Asp...
Computed Tomogr...
Echocardiograph...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Methotrexate
Nivolumab
Positron Emissi...
Rituximab
Ultrasound Imag...
18 Years - National Cancer Institute (NCI) View Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System NCT01596127 Leukemia
Lymphoid Malign...
Metastatic Mali...
Intrathecal Rit...
3 Years - M.D. Anderson Cancer Center View Co-administration of Propofol and Remifentanil for Lumbar Puncture in Children NCT00405522 Spinal Puncture
Propofol 2.0 mg...
Propofol 4.0 mg...
3 Years - 12 Years The Hospital for Sick Children View Diagnosis; Objective RespOnse; THErApy NCT05036564 Primary CNS Lym...
Lumbar puncture
18 Years - IRCCS San Raffaele View Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia NCT04872790 B Acute Lymphob...
B Acute Lymphob...
Mixed Phenotype...
Recurrent B Acu...
Recurrent Mixed...
Dasatinib
Methotrexate
Prednisone
Rituximab
Venetoclax
Blinatumomab
Bone Marrow Asp...
Lumbar Puncture
Biospecimen Col...
18 Years - OHSU Knight Cancer Institute View Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy NCT04359784 B-Cell Non-Hodg...
Anakinra
X-Ray Imaging
Positron Emissi...
Computed Tomogr...
Bone Marrow Asp...
Bone Marrow Bio...
Lumbar Puncture
Biospecimen Col...
18 Years - Fred Hutchinson Cancer Center View Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia NCT02003222 Acute Lymphobla...
B Acute Lymphob...
Allogeneic Hema...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Bone Marrow Bio...
Cyclophosphamid...
Cytarabine
Daunorubicin
Daunorubicin Hy...
Dexamethasone
Etoposide
Lumbar Puncture
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Rituximab
Vincristine
Vincristine Sul...
X-Ray Imaging
30 Years - 70 Years National Cancer Institute (NCI) View Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer NCT05130840 Breast Cancer
MRI
Lumbar puncture
18 Years - Memorial Sloan Kettering Cancer Center View NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma NCT05359211 Recurrent Diffu...
Recurrent Diffu...
Recurrent Grade...
Recurrent Prima...
Refractory Diff...
Refractory Diff...
Refractory Grad...
Refractory Prim...
Transformed Ind...
Cyclophosphamid...
Fludarabine
Lisocabtagene M...
Polymer-conjuga...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Bone Marrow Bio...
Bone Marrow Asp...
Lumbar Puncture
Computed Tomogr...
Positron Emissi...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center View Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer NCT05746325 Anatomic Stage ...
Metastatic Brea...
Metastatic Mali...
Digital Photogr...
Lumbar Puncture
Magnetic Resona...
Medical Device ...
18 Years - Mayo Clinic View A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control NCT04796935 Central Nervous...
Pseudotumor Cer...
Neurological Di...
Cancer
Obstetric Proce...
Orthopedic Proc...
Post-Dural Punc...
Tactile Imaging...
Control (palpat...
18 Years - IntuiTap Medical, Inc View Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia NCT02003222 Acute Lymphobla...
B Acute Lymphob...
Allogeneic Hema...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Bone Marrow Bio...
Cyclophosphamid...
Cytarabine
Daunorubicin
Daunorubicin Hy...
Dexamethasone
Etoposide
Lumbar Puncture
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Rituximab
Vincristine
Vincristine Sul...
X-Ray Imaging
30 Years - 70 Years National Cancer Institute (NCI) View Co-administration of Propofol and Remifentanil for Lumbar Puncture in Children NCT00405522 Spinal Puncture
Propofol 2.0 mg...
Propofol 4.0 mg...
3 Years - 12 Years The Hospital for Sick Children View Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma NCT04609046 Primary Diffuse...
Bone Marrow Asp...
Computed Tomogr...
Echocardiograph...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Methotrexate
Nivolumab
Positron Emissi...
Rituximab
Ultrasound Imag...
18 Years - National Cancer Institute (NCI) View Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome NCT05457556 Acute Lymphobla...
Acute Myeloid L...
Mixed Phenotype...
Myelodysplastic...
Biospecimen Col...
Bone Marrow Asp...
Busulfan
Cyclophosphamid...
Echocardiograph...
Fludarabine
Haploidentical ...
Lapine T-Lympho...
Lumbar Puncture
Matched Unrelat...
Melphalan
Methotrexate
Multigated Acqu...
Mycophenolate M...
Myeloablative C...
Quality-of-Life...
Questionnaire A...
Rituximab
T-Cell Depletio...
Tacrolimus
Thiotepa
Total-Body Irra...
6 Months - 21 Years Children's Oncology Group View Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced Cancer NCT02580045 Metastatic Canc...
Advanced Cancer
Brain Metastasi...
18 Years - Duke University View Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults NCT04530565 B Acute Lymphob...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Cyclophosphamid...
Cytarabine
Dasatinib
Dexamethasone
Doxorubicin Hyd...
Echocardiograph...
Electrocardiogr...
Lumbar Puncture
Mesna
Methotrexate
Multigated Acqu...
Ponatinib Hydro...
Prednisone
Vincristine Sul...
18 Years - 75 Years National Cancer Institute (NCI) View A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control NCT04796935 Central Nervous...
Pseudotumor Cer...
Neurological Di...
Cancer
Obstetric Proce...
Orthopedic Proc...
Post-Dural Punc...
Tactile Imaging...
Control (palpat...
18 Years - IntuiTap Medical, Inc View Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal Metastases NCT01713699 Meningeal Carci...
lumbar puncture
18 Years - The Netherlands Cancer Institute View Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer NCT05746325 Anatomic Stage ...
Metastatic Brea...
Metastatic Mali...
Digital Photogr...
Lumbar Puncture
Magnetic Resona...
Medical Device ...
18 Years - Mayo Clinic View A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma NCT06368817 Central Nervous...
Diabetes Insipi...
Pineal Region G...
Suprasellar Ger...
3-Dimensional C...
Biospecimen Col...
Carboplatin
Etoposide
Intensity-Modul...
Lumbar Puncture
Magnetic Resona...
Questionnaire A...
Surgical Proced...
3 Years - 30 Years Children's Oncology Group View Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell Therapy NCT05936229 Recurrent B Acu...
Recurrent B-Cel...
Refractory B Ac...
Refractory B-Ce...
Recurrent Mantl...
Refractory Mant...
Interferon Beta...
X-Ray Imaging
Echocardiograph...
Multigated Acqu...
Computed Tomogr...
Positron Emissi...
Lumbar Puncture
Bone Marrow Asp...
Bone Marrow Bio...
Biospecimen Col...
Biopsy
18 Years - Fred Hutchinson Cancer Center View A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma NCT06368817 Central Nervous...
Diabetes Insipi...
Pineal Region G...
Suprasellar Ger...
3-Dimensional C...
Biospecimen Col...
Carboplatin
Etoposide
Intensity-Modul...
Lumbar Puncture
Magnetic Resona...
Questionnaire A...
Surgical Proced...
3 Years - 30 Years Children's Oncology Group View A Study of SNDX-5613 in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia NCT05761171 Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Acute...
Recurrent Mixed...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Acut...
Refractory Mixe...
Biospecimen Col...
Bone Marrow Asp...
Calaspargase Pe...
Cytarabine
Echocardiograph...
Fludarabine Pho...
Hydrocortisone ...
Lumbar Puncture
Methotrexate
Multigated Acqu...
Prednisolone
Prednisone
Revumenib
Vincristine Sul...
1 Month - 6 Years Children's Oncology Group View Video/Audio Distraction Analgesia for Simulated Oncology Procedure Pain NCT00701571 Pain
Virtual Reality...
18 Years - University of Washington View Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia NCT04872790 B Acute Lymphob...
B Acute Lymphob...
Mixed Phenotype...
Recurrent B Acu...
Recurrent Mixed...
Dasatinib
Methotrexate
Prednisone
Rituximab
Venetoclax
Blinatumomab
Bone Marrow Asp...
Lumbar Puncture
Biospecimen Col...
18 Years - OHSU Knight Cancer Institute View Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes) for the Treatment of Primary Central Nervous System Lymphoma NCT05625594 Central Nervous...
Aspiration
Biospecimen Col...
Catheterization
CD19CAR-CD28-CD...
Computed Tomogr...
Cyclophosphamid...
Fludarabine
Leukapheresis
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
18 Years - City of Hope Medical Center View A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control NCT04796935 Central Nervous...
Pseudotumor Cer...
Neurological Di...
Cancer
Obstetric Proce...
Orthopedic Proc...
Post-Dural Punc...
Tactile Imaging...
Control (palpat...
18 Years - IntuiTap Medical, Inc View Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast Cancer NCT02598427 HER2 Positive U...
Asymptomatic or...
Pertuzumab
Trastuzumab
18 Years - Duke University View Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma NCT04609046 Primary Diffuse...
Bone Marrow Asp...
Computed Tomogr...
Echocardiograph...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Methotrexate
Nivolumab
Positron Emissi...
Rituximab
Ultrasound Imag...
18 Years - National Cancer Institute (NCI) View Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer NCT05130840 Breast Cancer
MRI
Lumbar puncture
18 Years - Memorial Sloan Kettering Cancer Center View Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma NCT05910801 Recurrent Mantl...
Refractory Mant...
Biopsy
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Computed Tomogr...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
Tafasitamab
Venetoclax
18 Years - Academic and Community Cancer Research United View Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast Cancer NCT02598427 HER2 Positive U...
Asymptomatic or...
Pertuzumab
Trastuzumab
18 Years - Duke University View Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal Metastases NCT01713699 Meningeal Carci...
lumbar puncture
18 Years - The Netherlands Cancer Institute View Diagnosis; Objective RespOnse; THErApy NCT05036564 Primary CNS Lym...
Lumbar puncture
18 Years - IRCCS San Raffaele View Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma NCT03919071 Anaplastic Astr...
Anaplastic Astr...
Anaplastic Gang...
Anaplastic Pleo...
Glioblastoma
Malignant Gliom...
WHO Grade 3 Gli...
Biospecimen Col...
Dabrafenib Mesy...
Lumbar Puncture
Magnetic Resona...
Radiation Thera...
Trametinib Dime...
12 Months - 21 Years National Cancer Institute (NCI) View Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma NCT05910801 Recurrent Mantl...
Refractory Mant...
Biopsy
Biospecimen Col...
Bone Marrow Asp...
Bone Marrow Bio...
Computed Tomogr...
Lenalidomide
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
Tafasitamab
Venetoclax
18 Years - Academic and Community Cancer Research United View Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia NCT02003222 Acute Lymphobla...
B Acute Lymphob...
Allogeneic Hema...
Biospecimen Col...
Blinatumomab
Bone Marrow Asp...
Bone Marrow Bio...
Cyclophosphamid...
Cytarabine
Daunorubicin
Daunorubicin Hy...
Dexamethasone
Etoposide
Lumbar Puncture
Mercaptopurine
Methotrexate
Pegaspargase
Prednisone
Rituximab
Vincristine
Vincristine Sul...
X-Ray Imaging
30 Years - 70 Years National Cancer Institute (NCI) View