Spots Global Cancer Trial Database for primary cns lymphoma
Every month we try and update this database with for primary cns lymphoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma | NCT05135858 | Primary Central... | Glucarpidase Methotrexate (M... | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL | NCT03740529 | Chronic Lymphoc... Waldenstrom Mac... Mantle Cell Lym... Marginal Zone L... B-cell Lymphoma Small Lymphocyt... | Pirtobrutinib Venetoclax Rituximab | 18 Years - | Eli Lilly and Company | |
| Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma | NCT05841914 | Vitreoretinal L... | 18 Years - | University of Luebeck | ||
| Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma | NCT04443829 | Primary CNS Lym... | CD19CAR T-cells | 16 Years - | University College, London | |
| Temozolomide in Treatment of Patients With Primary Central Nervous System Lymphoma | NCT02934204 | Primary CNS Lym... | methotrexate temozolomide | 18 Years - 75 Years | Guangdong Provincial People's Hospital | |
| RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL | NCT05425654 | Primary CNS Lym... | Rituximab, Meth... | 18 Years - 70 Years | National Research Center for Hematology, Russia | |
| Study of Lenalidomide/Rituximab Maintenance for Transplantation Ineligible Patients With PCNSL. | NCT04627753 | Primary CNS Lym... | Rituximab, lena... | 19 Years - | Samsung Medical Center | |
| Diagnosis; Objective RespOnse; THErApy | NCT05036564 | Primary CNS Lym... | Lumbar puncture | 18 Years - | IRCCS San Raffaele | |
| High-Dose (HD) Methotrexate (MTX) Induction Chemotherapy Followed by Alternative HD MTX-based and HD Cytarabine-based Combination Consolidation Chemotherapy for Newly Diagnosed Primary CNS Lymphoma; CISL 10-01 Study | NCT01083342 | CNS Lymphoma | MTX, MVD, VIA | 20 Years - 70 Years | Samsung Medical Center | |
| Temozolomide in Treatment of Patients With Primary Central Nervous System Lymphoma | NCT02934204 | Primary CNS Lym... | methotrexate temozolomide | 18 Years - 75 Years | Guangdong Provincial People's Hospital | |
| Treatment of Recurrent Primary or Secondary Central Nervous System (CNS) Lymphoma With ALIMTA (Pemetrexed) | NCT00916630 | Central Nervous... | pemetrexed | 18 Years - | Massachusetts General Hospital | |
| Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma | NCT04443829 | Primary CNS Lym... | CD19CAR T-cells | 16 Years - | University College, London | |
| Treatment of Primary CNS Lymphoma ( FTD ) | NCT05274139 | Primary CNS Lym... | HD-MTX-Ara-C re... FTD regimen | 14 Years - 69 Years | Zhengzhou University | |
| RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL | NCT05425654 | Primary CNS Lym... | Rituximab, Meth... | 18 Years - 70 Years | National Research Center for Hematology, Russia | |
| Treatment of Primary CNS Lymphoma ( FTD ) | NCT05274139 | Primary CNS Lym... | HD-MTX-Ara-C re... FTD regimen | 14 Years - 69 Years | Zhengzhou University | |
| Rituximab,Zanubrutinib in Combination With Lenalidomide, Followed by Zanubrutinib or Lenalidomide Maintenance in Patients With Primary or Secondary CNS Lymphoma | NCT04938297 | Central Nervous... | Rituximab, Lena... Lenalidomide, Z... Lenalidomide | 18 Years - | Henan Cancer Hospital | |
| Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma | NCT00193973 | Primary Central... | Idarubicin, Met... Radiation Thera... | 18 Years - 70 Years | Trans Tasman Radiation Oncology Group | |
| High-Dose (HD) Methotrexate (MTX) Induction Chemotherapy Followed by Alternative HD MTX-based and HD Cytarabine-based Combination Consolidation Chemotherapy for Newly Diagnosed Primary CNS Lymphoma; CISL 10-01 Study | NCT01083342 | CNS Lymphoma | MTX, MVD, VIA | 20 Years - 70 Years | Samsung Medical Center | |
| Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma | NCT05841914 | Vitreoretinal L... | 18 Years - | University of Luebeck | ||
| 19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers | NCT04464200 | Diffuse Large B... Primary Mediast... Transformed Fol... Chronic Lymphoc... Indolent Non-Ho... Marginal Zone L... Waldenstrom Mac... Burkitt's Lymph... Primary CNS Lym... | 19(T2)28z1xx CA... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Venetoclax and Obinutuzumab for Relapsed/Refractory Primary CNS Lymphoma | NCT04073147 | Primary CNS Lym... | Venetoclax Obinutuzumab | 18 Years - 85 Years | Klinikum Stuttgart | |
| Temozolomide in Treatment of Patients With Primary Central Nervous System Lymphoma | NCT02934204 | Primary CNS Lym... | methotrexate temozolomide | 18 Years - 75 Years | Guangdong Provincial People's Hospital | |
| Study Of Durvalumab and Lenalidomide In R/R EBV Associated DLBCL Subtypes, Primary CNS And Testicular DLBCL | NCT03212807 | EBV Related Non... Primary CNS Lym... Primary Testicu... | Durvalumab Lenalidomide | 21 Years - 80 Years | Singapore General Hospital | |
| Feasibility of Acquiring Hyperpolarized Imaging in Patients With Primary CNS Lymphoma | NCT04656431 | Primary CNS Lym... | Hyperpolarized ... Magnetic resona... | 18 Years - | University of California, San Francisco | |
| A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL | NCT03740529 | Chronic Lymphoc... Waldenstrom Mac... Mantle Cell Lym... Marginal Zone L... B-cell Lymphoma Small Lymphocyt... | Pirtobrutinib Venetoclax Rituximab | 18 Years - | Eli Lilly and Company | |
| Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost | NCT04006561 | Primary CNS Lym... Brain Lymphoma | A treatment pro... | 18 Years - 80 Years | Chang Gung Memorial Hospital | |
| Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma | NCT05135858 | Primary Central... | Glucarpidase Methotrexate (M... | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Treatment of Primary CNS Lymphoma ( FTD ) | NCT05274139 | Primary CNS Lym... | HD-MTX-Ara-C re... FTD regimen | 14 Years - 69 Years | Zhengzhou University | |
| Diagnosis; Objective RespOnse; THErApy | NCT05036564 | Primary CNS Lym... | Lumbar puncture | 18 Years - | IRCCS San Raffaele |
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