Spots Global Cancer Trial Database for CRP-guided Transanal Drainage Removal After Rectal Surgery

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Trial Identification

Brief Title: CRP-guided Transanal Drainage Removal After Rectal Surgery

Official Title: A Single Arm Study to Investigate the Safety and Efficacy of C Reactive Protein (CRP) Guided Transanal Drainage Tube (TDT) Removal for Anastomotic Leak (AL) Prevention Following Laparoscopic Anterior Resection for Rectal Carcinoma

Study ID: NCT05502354

Conditions

Rectal Cancer

Anastomotic Leak

Interventions

removal of transanal drainage tube

Study Description

Brief Summary: Transanal drainage tube (TDT) has the benefit of reducing intraluminal pressure after rectal surgery and may provide ideal regional environment for anastomotic healing. Postoperative C-reactive protein (CRP) trajectory has a high negative predictive value of 0.99 for ruling out anastomotic leak (AL). Previously, TDT was removed at the surgeon's own discretion. In the present study, we design a single arm study to investigate the safety and efficacy of CRP-guided TDT removal for AL prevention following laparoscopic anterior resection for rectal carcinoma

Detailed Description: