Spots Global Cancer Trial Database for anastomotic leak
Every month we try and update this database with for anastomotic leak cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Microbiota-anastomotic Leak Among Colorectal Surgery Patients : Pilot Study | NCT03496441 | Colorectal Canc... Inflammatory Bo... Microbiota Anastomotic Lea... | Fecal sample co... | 18 Years - 90 Years | Centre hospitalier de l'Université de Montréal (CHUM) | |
| The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage | NCT03325361 | Rectal Cancer Rectal Neoplasm... Anastomotic Lea... | Tube drain inse... | - | University of Rome Tor Vergata | |
| Anastomotic Leakage After Anterior Resection for Rectal Cancer - Predictive Biomarkers and Rectal Blood Flow | NCT02401100 | Anastomotic Lea... | - | Umeå University | ||
| Tisseel® as a Reinforcement of Esophagojejunal Anastomoses | NCT03733639 | Gastric Cancer Anastomotic Lea... | Tisseel No Tisseel | 18 Years - | Germans Trias i Pujol Hospital | |
| Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes | NCT04418739 | Pancreaticoduod... Pancreatic Fist... Delayed Gastric... Pancreatic Canc... Anastomotic Lea... | Human albumin | - | Universiti Kebangsaan Malaysia Medical Centre | |
| Intracorporeal Versus Extracorporeal Anastomotic After Laparoscopic Right Colectomy | NCT05493033 | Colon Cancer | Intracorporeal ... Extracorporeal ... | 18 Years - 80 Years | Beijing Friendship Hospital | |
| Quantitative ICG Fluorescence Angiography in Colorectal Surgery | NCT05153954 | Colorectal Canc... Anastomotic Lea... | Quantitative In... | 18 Years - | Zealand University Hospital | |
| CRP-guided Transanal Drainage Removal After Rectal Surgery | NCT05502354 | Rectal Cancer Anastomotic Lea... | removal of tran... | 18 Years - 75 Years | Qilu Hospital of Shandong University | |
| Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis | NCT04695964 | Ulcerative Coli... Colorectal Canc... Crohn Disease Familial Adenom... Ulcerative Coli... Ulcerative Coli... Crohn Colitis Ileal Pouch | ICG-NIRF Imagin... | 18 Years - | Charite University, Berlin, Germany | |
| Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer | NCT02770911 | Rectal Carcinom... Laparoscopy Anastomotic Lea... | without "Dog Ea... with "Dog Ear" ... | 18 Years - 80 Years | Fujian Medical University | |
| Tisseel® as a Reinforcement of Esophagojejunal Anastomoses | NCT03733639 | Gastric Cancer Anastomotic Lea... | Tisseel No Tisseel | 18 Years - | Germans Trias i Pujol Hospital | |
| Evaluation of AL Prediction for Rectal Cancer | NCT05610904 | Anastomotic Lea... | Prediction mode... | 18 Years - 75 Years | Changhai Hospital | |
| Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy | NCT01551433 | Esophageal Canc... | wireless pulse ... | 21 Years - | Memorial Sloan Kettering Cancer Center | |
| Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation | NCT06348381 | Esophageal Neop... Anastomotic Lea... Recurrent Laryn... Anastomotic Ste... Endoscopic Eval... | No intervention | 18 Years - 80 Years | Shanghai Chest Hospital | |
| THREE-row Circular STAPLER in Low Anterior Resection for Rectal Cancer | NCT03910699 | Anastomotic Lea... Anastomotic Hae... Anastomotic Com... Rectal Neoplasm... Staple Misfire Anastomosis Anastomotic Ste... | Three-row circu... Two-row circula... | 18 Years - 85 Years | Russian Society of Colorectal Surgeons | |
| Effect of Neck Flexion on Esophagogastric Anastomotic Leakage After MIE | NCT02418052 | Esophageal Neop... Esophagectomy Anastomotic Lea... | neck flexion | 18 Years - 75 Years | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | |
| Study for the Efficacy and Security Analysis in the Protection of Ileocolic Anastomosis Conducted in Laparoscopic Right Hemicolectomy Because of Colon Cancer, Using a NHS-PEG Coated Collagen Patch. | NCT04109105 | Adenocarcinoma ... | NHS-PEG coated ... | 18 Years - | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | |
| Quantification of Anastomostic Blood Flow With Fluorescence Imaging in Low Anterior Resection for Rectal Cancer | NCT05627934 | Anastomotic Lea... | qICG | 18 Years - | Odense University Hospital | |
| Endoscopic Visualisation of Anastomosis in Colorectal Cancer Surgery | NCT04738240 | Rectal Cancer Colorectal Canc... Anastomotic Lea... Intraoperative ... | Intra-operative... | 18 Years - | University of Plymouth | |
| Early Dehiscence Markers in Ovarian Cancer Surgery | NCT03131492 | Ovarian Neoplas... Anastomotic Lea... | Blood test | 18 Years - | Hospital Universitari Vall d'Hebron Research Institute | |
| Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation | NCT06348381 | Esophageal Neop... Anastomotic Lea... Recurrent Laryn... Anastomotic Ste... Endoscopic Eval... | No intervention | 18 Years - 80 Years | Shanghai Chest Hospital | |
| The Effect of Inulin Supplementation on Colorectal Surgery Outcomes | NCT05860322 | Anastomotic Com... | Inulin Placebo | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
| Transanal Inspection and Management of Low ColoRectal Anastomosis Performed With a New Technique | NCT02879370 | Anastomotic Lea... | Transanal Inspe... | 18 Years - | University of Rome Tor Vergata | |
| Non-invasive Detection of Anastomotic Leakage | NCT03203434 | Anastomotic Lea... | Urinary volatil... | 18 Years - 90 Years | Amsterdam UMC, location VUmc | |
| Microbiome Analysis in esoPhageal, PancreatIc and Colorectal CaNcer Patients Undergoing Gastrointestinal Surgery | NCT04189393 | Gastrointestina... Colorectal Canc... Pancreatic Canc... Esophageal Canc... Rectum Neoplasm Esophageal Neop... Pancreatic Duct... Colonic Neoplas... Gastrointestina... Microbiota Anastomotic Lea... | 18 Years - | Radboud University Medical Center | ||
| Evaluation of AL Prediction for Rectal Cancer | NCT05610904 | Anastomotic Lea... | Prediction mode... | 18 Years - 75 Years | Changhai Hospital | |
| Serial Endoscopic Surveillance & Direct Topical Antibiotics to Define the Role of Microbes in Anastomotic Healing | NCT02682485 | Anastomotic Lea... Rectal Cancer | Cipro, metronid... Serial Endoscop... Saline | 18 Years - | University of Chicago | |
| Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery | NCT04490668 | Gastric Cancer Anastomotic Lea... | Human albumin | 18 Years - 90 Years | Ruijin Hospital | |
| Anastomotic Leakage and Enhanced Recovery Pathways After Colorectal Surgery | NCT03771456 | Colorectal Neop... Anastomotic Lea... Surgery--Compli... | Colorectal rese... | - | Ospedale C & G Mazzoni | |
| Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma. | NCT03529266 | Esophageal Canc... Gastroesophagea... Anastomotic Lea... | Porcine Fibrin ... Surgery | 18 Years - 80 Years | Sun Yat-sen University | |
| The Impact of Transanal Decompression Tube Placement After Colorectal Anastomosis: A Randomized Trial | NCT04890015 | Colorectal Canc... Postoperative C... Anastomotic Lea... Anastomotic Com... | Intraoperative ... | 18 Years - | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | |
| Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis | NCT04695184 | Ulcerative Coli... Colorectal Canc... Crohn Disease Familial Adenom... Crohn Colitis Ileal Pouch | ICG-NIRF Imagin... | 18 Years - | Charite University, Berlin, Germany | |
| Transanal Reinforcement of Low Rectal Anastomosis in Rectal Cancer Surgery | NCT02279771 | Rectal Cancer | transanal anast... protective ileo... a circular anal... | 30 Years - 80 Years | Societa Italiana di Chirurgia ColoRettale | |
| Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses | NCT04709445 | Bowel Obstructi... Bowel Ischemia Diverticulitis Abnormality of ... Symptomatic Dis... Stoma Ileostomy Cancer of the G... Crohn Disease Ulcerative Coli... Familial Adenom... Pancreatic Neop... Hepatobiliary N... | ICG-NIRF Imagin... | 18 Years - | Charite University, Berlin, Germany | |
| The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study | NCT04985981 | Anastomotic Lea... Colorectal Canc... Diverticulosis Crohn Disease Ulcerative Coli... Mesenteric Isch... | 18 Years - | Kantonsspital Winterthur KSW | ||
| Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer | NCT05943444 | Rectal Neoplasm... Low Anterior Re... Anastomotic Lea... Quality of Life | Parks technique Bacon technique | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Anastomotic Leak Testing in Gastrectomy | NCT04292496 | Anastomotic Lea... Gastric Cancer Surgery Testing, Realit... Gastroscopy | Introperative l... | 18 Years - 85 Years | Nanchong Central Hospital | |
| Evaluation of AL Prediction for Rectal Cancer | NCT05610904 | Anastomotic Lea... | Prediction mode... | 18 Years - 75 Years | Changhai Hospital | |
| Tisseel® as a Reinforcement of Esophagojejunal Anastomoses | NCT03733639 | Gastric Cancer Anastomotic Lea... | Tisseel No Tisseel | 18 Years - | Germans Trias i Pujol Hospital | |
| Prediction of Intra-abdominal Infectious Complication by Drainage Fluid Analysis | NCT03862378 | Complication Anastomotic Lea... Intraabdominal ... Inflammatory Re... Gastrointestina... | 18 Years - | Peking University | ||
| Quantification of Anastomostic Blood Flow With Fluorescence Imaging in Low Anterior Resection for Rectal Cancer | NCT05627934 | Anastomotic Lea... | qICG | 18 Years - | Odense University Hospital | |
| Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections | NCT04550156 | Colorectal Diso... Surgery--Compli... Colorectal Canc... Anastomotic Lea... Complication of... | Colorectal Bund... | 18 Years - | University Hospital, Basel, Switzerland | |
| Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer | NCT06097078 | Esophageal Canc... Esophagus Cance... Anastomotic Lea... | Eso-SPONGE® | 18 Years - | Aesculap AG | |
| Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes | NCT04418739 | Pancreaticoduod... Pancreatic Fist... Delayed Gastric... Pancreatic Canc... Anastomotic Lea... | Human albumin | - | Universiti Kebangsaan Malaysia Medical Centre | |
| Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection | NCT04751149 | Rectal Cancer Retention, Urin... Urinary Tract I... Surgical Site I... Anastomotic Lea... | Removal of Urin... | 18 Years - 85 Years | Hospital Donostia | |
| Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | NCT02905968 | Rectal Cancer | transanual tube... | 18 Years - 75 Years | Fudan University | |
| Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy | NCT02937389 | Esophageal Neop... Constriction Anastomotic Lea... Ischemia | Patients after ... | 20 Years - 84 Years | Nagasaki University | |
| The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study | NCT04985981 | Anastomotic Lea... Colorectal Canc... Diverticulosis Crohn Disease Ulcerative Coli... Mesenteric Isch... | 18 Years - | Kantonsspital Winterthur KSW | ||
| ECO-LEAK Technique: Early Detection of Colorectal Anastomotic Leakage by Transvaginal Ultrasound | NCT05942209 | Gynecologic Can... Anastomotic Lea... Cytoreductive S... | ECO-LEAK transv... ECO-LEAK with C... CT-Scan or rect... | 21 Years - 99 Years | Instituto de Investigacion Sanitaria La Fe | |
| Predictive Factors for Anastomotic Leakage After Colorectal Surgery | NCT02347735 | Anastomotic Lea... Colorectal Canc... Anastomotic Lea... Colorectal Neop... Colorectal Carc... Colorectal Tumo... | No intervention... | 18 Years - | Maastricht University Medical Center | |
| Application of Left Colic Artery Preservation, Anastomotic Reinforcing Sutures and Transanal Tube in Robotic Low Anterior Resection | NCT03609710 | Rectal Cancer | Transanal tube ... Left colic arte... Anastomotic rei... Robotic surgery | 18 Years - 75 Years | Fudan University | |
| Endoscopic Visualisation of Anastomosis in Colorectal Cancer Surgery | NCT04738240 | Rectal Cancer Colorectal Canc... Anastomotic Lea... Intraoperative ... | Intra-operative... | 18 Years - | University of Plymouth | |
| Early Dehiscence Markers in Ovarian Cancer Surgery | NCT03131492 | Ovarian Neoplas... Anastomotic Lea... | Blood test | 18 Years - | Hospital Universitari Vall d'Hebron Research Institute | |
| Early Detection of Postoperative Anastomotic Leak by CT | NCT03632395 | Anastomotic Lea... | computed tomogr... | 18 Years - 85 Years | Ruijin Hospital | |
| Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy | NCT01551433 | Esophageal Canc... | wireless pulse ... | 21 Years - | Memorial Sloan Kettering Cancer Center | |
| Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial | NCT05411783 | Anastomotic Lea... Anastomotic Lea... Anastomotic Lea... Colon Cancer Colon Neoplasm Rectum Cancer Rectum Neoplasm Colorectal Canc... | Low tie of IMV | - | San Carlo di Nancy Hospital | |
| Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation | NCT06348381 | Esophageal Neop... Anastomotic Lea... Recurrent Laryn... Anastomotic Ste... Endoscopic Eval... | No intervention | 18 Years - 80 Years | Shanghai Chest Hospital | |
| Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing | NCT02907385 | Rectal Cancer Anastomotic Lea... | LifeSeal™ Kit | 21 Years - | LifeBond Ltd. | |
| Early Detection of Postoperative Anastomotic Leak by CT | NCT03632395 | Anastomotic Lea... | computed tomogr... | 18 Years - 85 Years | Ruijin Hospital | |
| Risk of NSAIDs on Anastomotic Leak for Rectal Surgery | NCT06155175 | Anastomotic Lea... Anti-Inflammato... | 18 Years - | Third Military Medical University | ||
| Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer | NCT05943444 | Rectal Neoplasm... Low Anterior Re... Anastomotic Lea... Quality of Life | Parks technique Bacon technique | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Predictive Factors for Anastomotic Leakage After Colorectal Surgery | NCT02347735 | Anastomotic Lea... Colorectal Canc... Anastomotic Lea... Colorectal Neop... Colorectal Carc... Colorectal Tumo... | No intervention... | 18 Years - | Maastricht University Medical Center | |
| Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection | NCT04751149 | Rectal Cancer Retention, Urin... Urinary Tract I... Surgical Site I... Anastomotic Lea... | Removal of Urin... | 18 Years - 85 Years | Hospital Donostia | |
| Intracorporeal Versus Extracorporeal Anastomotic After Laparoscopic Right Colectomy | NCT05493033 | Colon Cancer | Intracorporeal ... Extracorporeal ... | 18 Years - 80 Years | Beijing Friendship Hospital | |
| Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy | NCT02937389 | Esophageal Neop... Constriction Anastomotic Lea... Ischemia | Patients after ... | 20 Years - 84 Years | Nagasaki University | |
| Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation | NCT06348381 | Esophageal Neop... Anastomotic Lea... Recurrent Laryn... Anastomotic Ste... Endoscopic Eval... | No intervention | 18 Years - 80 Years | Shanghai Chest Hospital | |
| Evaluation of AL Prediction for Rectal Cancer | NCT05610904 | Anastomotic Lea... | Prediction mode... | 18 Years - 75 Years | Changhai Hospital | |
| Indocyanine Green Fluorescent Imaging in Robotic Assisted Rectosigmoidal Resection; a Multicenter Assessment of Interobserver Variation and Comparison With Computer-based Pixel Analysis | NCT04766060 | Colorectal Canc... Anastomotic Lea... | Fluorescent Ima... | 18 Years - | Odense University Hospital | |
| Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | NCT02905968 | Rectal Cancer | transanual tube... | 18 Years - 75 Years | Fudan University | |
| A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes | NCT06227871 | Pancreatic Trau... Pancreatic Duct... Pancreas Necros... Pancreas Cyst Pancreas; Fistu... Pancreas Absces... Intra-Abdominal... Anastomotic Lea... Pancreas Injury | Exploratory lap... | 18 Years - | Kern Medical Center | |
| The Effect of Inulin Supplementation on Colorectal Surgery Outcomes | NCT05860322 | Anastomotic Com... | Inulin Placebo | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
| Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage (PLACE030) | NCT03847857 | Esophageal Anas... | Porcine Fibrin ... McKeown esophag... | 18 Years - 75 Years | Sun Yat-sen University | |
| Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy | NCT02937389 | Esophageal Neop... Constriction Anastomotic Lea... Ischemia | Patients after ... | 20 Years - 84 Years | Nagasaki University | |
| Prediction of Abdominal Complications After GastroEnterological Surgery | NCT03828266 | Complication Anastomotic Lea... Gastrointestina... | No intervention | 18 Years - | Peking University | |
| Non-invasive Detection of Anastomotic Leakage | NCT03203434 | Anastomotic Lea... | Urinary volatil... | 18 Years - 90 Years | Amsterdam UMC, location VUmc | |
| Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)? | NCT03316677 | ColoRectal Canc... Colonic Diverti... Anastomotic Lea... Anastomotic Com... Anastomosis | Intraoperative ... Stapled colorec... | 18 Years - | Meir Medical Center | |
| Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage (PLACE030) | NCT03847857 | Esophageal Anas... | Porcine Fibrin ... McKeown esophag... | 18 Years - 75 Years | Sun Yat-sen University | |
| Microbiome Analysis in esoPhageal, PancreatIc and Colorectal CaNcer Patients Undergoing Gastrointestinal Surgery | NCT04189393 | Gastrointestina... Colorectal Canc... Pancreatic Canc... Esophageal Canc... Rectum Neoplasm Esophageal Neop... Pancreatic Duct... Colonic Neoplas... Gastrointestina... Microbiota Anastomotic Lea... | 18 Years - | Radboud University Medical Center | ||
| Microbiota-anastomotic Leak Among Colorectal Surgery Patients : Pilot Study | NCT03496441 | Colorectal Canc... Inflammatory Bo... Microbiota Anastomotic Lea... | Fecal sample co... | 18 Years - 90 Years | Centre hospitalier de l'Université de Montréal (CHUM) | |
| Serial Endoscopic Surveillance & Direct Topical Antibiotics to Define the Role of Microbes in Anastomotic Healing | NCT02682485 | Anastomotic Lea... Rectal Cancer | Cipro, metronid... Serial Endoscop... Saline | 18 Years - | University of Chicago |
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