Spots Global Cancer Trial Database for Microbiome and Rectal Cancer
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Trial Identification
Brief Title: Microbiome and Rectal Cancer
Official Title: Rectal Microbiome Variability Among Rectal Cancer Cohorts Including Complete Clinical Responders, Pathologic Responders, and Early Recurrence
Study ID: NCT04223102
Interventions
Study Description
Brief Summary: The purpose of our study is to determine if an association exists between the microbiome of those with rectal adenocarcinoma who are complete pathologic responders and those who have a partial or no response to neoadjuvant therapy.
Detailed Description: This study will help to further elucidate the association of bacteria with rectal cancer, while also characterizing the genes associated with that risk. Furthermore it will attempt to better understand which patients may have an optimal response to neoadjuvant chemoradiation allowing for possible predictive metagenomics evaluation, investigators may be able to augment treatments as well as provide recommendations for the success and cost effectiveness of cancer care.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Tampa General Hospital, Tampa, Florida, United States
University of South Florida - South Tampa Campus, Tampa, Florida, United States
University of South Florida, Tampa, Florida, United States
Contact Details
Name: James R Williams, MD
Affiliation: University of South Florida
Role: PRINCIPAL_INVESTIGATOR
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