Spots Global Cancer Trial Database for locally advanced malignant neoplasm
Every month we try and update this database with for locally advanced malignant neoplasm cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Healthy Bones Study | NCT01973673 | Locally Advance... | Bone health edu... | 18 Years - | University Health Network, Toronto | |
| A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors | NCT03295942 | Locally Advance... Metastatic Canc... | OMP-336B11 | 21 Years - | Mereo BioPharma | |
| A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors | NCT03295942 | Locally Advance... Metastatic Canc... | OMP-336B11 | 21 Years - | Mereo BioPharma | |
| Financial Distress in Advanced Cancer Patients | NCT04053517 | Advanced Malign... Locally Advance... Metastatic Mali... Recurrent Malig... Refractory Mali... | Medical Chart R... Quality-of-Life... Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer | NCT04112836 | Pancreatic Canc... Exocrine Pancre... Metastatic Panc... Chemotherapy Malnutrition Locally Advance... | 18 Years - | Moscow Clinical Scientific Center | ||
| A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers | NCT04260802 | Cancer Neoplasms Metastatic Canc... Triple Negative... Gastric Cancer Cervical Cancer Ovarian Cancer Hepatocellular ... Squamous Cell C... Urothelial Carc... Urothelial Neop... Non Small Cell ... Renal Cell Carc... Locally Advance... Locally Advance... Squamous Cell C... Sarcoma Merkel Cell Car... Bladder Cancer | OC-001 OC-001 in Combi... | 18 Years - | Ocellaris Pharma, Inc. | |
| Ride to Care - Quality of Life With Transportation for RT | NCT03849742 | Locally Advance... Metastatic Mali... | Quality-of-Life... Questionnaire A... Supportive Care | 18 Years - | University of California, San Francisco | |
| Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the Head and Neck | NCT02236936 | Squamous Cell C... Squamous Cell C... Laryngeal Squam... Laryngeal Squam... Oropharyngeal S... Oropharyngeal S... Squamous Cell C... Squamous Cell C... Locally Advance... | Standard care o... Parenteral over... Cetuximab Cisplatin Radiotherapy | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Trial of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer | NCT01675999 | Colon Cancer Locally Advance... | Perioperative s... Perioperative F... Surgery followe... | 18 Years - 76 Years | Assistance Publique - Hôpitaux de Paris | |
| Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits | NCT03856060 | Advanced Malign... Locally Advance... Malignant Neopl... Metastatic Mali... Recurrent Malig... | Questionnaire A... Video | 18 Years - | M.D. Anderson Cancer Center | |
| A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors | NCT03238027 | Solid Tumor Metastatic Tumo... Locally Advance... Unresectable Ma... | Axatilimab Durvalumab | 18 Years - | Syndax Pharmaceuticals | |
| Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced Cancer | NCT02823652 | Advanced Malign... Locally Advance... | standard geneti... Genetic Counsel... Genetic Testing Internet-Based ... Survey Administ... | 18 Years - | Eastern Cooperative Oncology Group | |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy | NCT01847001 | Locally Advance... Breast Cancer | Propranolol DOT imaging Paclitaxel Nab-paclitaxel Trastuzumab Pertuzumab Doxorubicin Cyclophosphamid... Surgery Premedication Anti-nausea the... Pegfilgrastim | 18 Years - | Columbia University | |
| Trial of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer | NCT01675999 | Colon Cancer Locally Advance... | Perioperative s... Perioperative F... Surgery followe... | 18 Years - 76 Years | Assistance Publique - Hôpitaux de Paris | |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy | NCT01847001 | Locally Advance... Breast Cancer | Propranolol DOT imaging Paclitaxel Nab-paclitaxel Trastuzumab Pertuzumab Doxorubicin Cyclophosphamid... Surgery Premedication Anti-nausea the... Pegfilgrastim | 18 Years - | Columbia University | |
| A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors | NCT01325558 | Locally Advance... Malignant Solid... | ALT-836 in comb... | 18 Years - | Altor BioScience | |
| Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center | NCT03671226 | Advanced Malign... Caregiver Locally Advance... Metastatic Mali... | Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| Neo-adjuvant Erbitux-based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer | NCT01440270 | Locally Advance... Oral Cancer Oropharyngeal C... | Neo-adjuvant Er... | 18 Years - 75 Years | Shanghai Jiao Tong University School of Medicine | |
| Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care | NCT03743649 | Delirium Locally Advance... Metastatic Mali... Recurrent Malig... | Haloperidol Lorazepam Placebo Quality-of-Life... Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors | NCT03108131 | Skin Squamous C... Appendix Adenoc... Rare Lesion Locally Advance... Locally Advance... Metastatic Mali... Metastatic Skin... Metastatic Smal... Rare Neoplastic... Refractory Mali... Stage IV Small ... Unresectable Ma... | Atezolizumab Cobimetinib | 18 Years - | M.D. Anderson Cancer Center | |
| Ride to Care - Quality of Life With Transportation for RT | NCT03849742 | Locally Advance... Metastatic Mali... | Quality-of-Life... Questionnaire A... Supportive Care | 18 Years - | University of California, San Francisco | |
| Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma | NCT01333709 | Locally Advance... Rectal Carcinom... | Induction trich... Early tumor res... Radiochemothera... Radiochemothera... Radical proctec... | 18 Years - | Institut du Cancer de Montpellier - Val d'Aurelle | |
| Chemoimmunotherapy and Radiation in Pancreatic Cancer | NCT01903083 | Locally Advance... | Tadalafil Gemcitabine Radiation Pancreaticoduod... | 18 Years - | Providence Health & Services | |
| Neo-adjuvant Erbitux-based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer | NCT01440270 | Locally Advance... Oral Cancer Oropharyngeal C... | Neo-adjuvant Er... | 18 Years - 75 Years | Shanghai Jiao Tong University School of Medicine | |
| Microbiome and Rectal Cancer | NCT04223102 | Rectal Cancer Locally Advance... | Tissue collecti... | 18 Years - | University of South Florida | |
| Positron Emission Tomography (PET) During Radio-chemotherapy to Treat Otorhinolaryngological Cancer | NCT02469922 | Malignant Neopl... Locally Advance... | Positron emissi... radiochemothera... | 18 Years - 75 Years | Center Eugene Marquis | |
| Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer | NCT03170115 | Rectal Cancer, ... Locally Advance... Chemoradiation | Aspirin Placebo Oral Ta... | 18 Years - 75 Years | Instituto Nacional de Cancer, Brazil | |
| Induction Chemotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT03815903 | Locally Advance... | Induction chemo... Chemoradiothera... | 18 Years - | Barretos Cancer Hospital | |
| Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center | NCT03671226 | Advanced Malign... Caregiver Locally Advance... Metastatic Mali... | Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the Head and Neck | NCT02236936 | Squamous Cell C... Squamous Cell C... Laryngeal Squam... Laryngeal Squam... Oropharyngeal S... Oropharyngeal S... Squamous Cell C... Squamous Cell C... Locally Advance... | Standard care o... Parenteral over... Cetuximab Cisplatin Radiotherapy | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Olaparib and Radiotherapy in Inoperable Breast Cancer | NCT02227082 | Locally Advance... Inflammatory Br... Triple-Negative... | radiotherapy olaparib | 18 Years - | The Netherlands Cancer Institute | |
| Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment | NCT03619668 | Rectal Cancer Rectal Adenocar... Locally Advance... | 18 Years - | Aalborg University Hospital | ||
| Pre-Operative Or Peri-Operative Dox Regimen In Patients With Locally Advanced Resectable Gastric Cancer | NCT01876927 | Gastric Cancer Locally Advance... | DOX 4 cycles - ... DOX 2 cycles - ... | 18 Years - 75 Years | Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori | |
| Extraperitoneal Para-aortic Lymph Node Dissection (EPLND) for Cervix | NCT01365156 | Cervical Squamo... Adenosquamous C... Adenocarcinoma Locally Advance... Cervical Cancer | Extraperitoneal... Chemoradiation | 18 Years - | M.D. Anderson Cancer Center | |
| Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer | NCT01836432 | Pancreatic Canc... Pancreatic Carc... Locally Advance... | FOLFIRINOX Algenpantucel-L... 5-FU Chemoradia... Gemcitabine Capecitabine Nab-Paclitaxel | 18 Years - | Lumos Pharma | |
| Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer | NCT04112836 | Pancreatic Canc... Exocrine Pancre... Metastatic Panc... Chemotherapy Malnutrition Locally Advance... | 18 Years - | Moscow Clinical Scientific Center | ||
| Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer | NCT02404051 | Metastatic Brea... Breast Cancer Hormone Recepto... Human Epidermal... Locally Advance... | Everolimus Exemestane Fulvestrant | 18 Years - | Consorzio Oncotech | |
| Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer | NCT03240861 | HLA-A*0201 Posi... Locally Advance... NY-ESO-1 Positi... Unresectable Ma... Sarcoma | 18F-FHBG Aldesleukin Busulfan Cellular Therap... Computed Tomogr... Filgrastim Fludarabine Leukapheresis Plerixafor Positron Emissi... | 16 Years - | Jonsson Comprehensive Cancer Center | |
| Adjuvant Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Gastric Cancer | NCT02672865 | Locally Advance... Gastric Cancer | Hyperthermic In... | 18 Years - 75 Years | Loma Linda University | |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy | NCT01847001 | Locally Advance... Breast Cancer | Propranolol DOT imaging Paclitaxel Nab-paclitaxel Trastuzumab Pertuzumab Doxorubicin Cyclophosphamid... Surgery Premedication Anti-nausea the... Pegfilgrastim | 18 Years - | Columbia University | |
| Registry Trial to Evaluate the Safety and Efficacy of Hyperthermia in Locally Advanced Cancers | NCT05099809 | Locally Advance... | Hyperthermia | 18 Years - | Mahatma Gandhi Institute of Medical Sciences | |
| Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment | NCT03619668 | Rectal Cancer Rectal Adenocar... Locally Advance... | 18 Years - | Aalborg University Hospital | ||
| Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer | NCT01566799 | Locally Advance... | Metformin | 18 Years - 70 Years | Instituto Nacional de Cancerologia de Mexico | |
| Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings | NCT04186884 | Advanced Malign... Locally Advance... Metastatic Mali... Recurrent Malig... | Quality-of-Life... Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| Positron Emission Tomography (PET) During Radio-chemotherapy to Treat Otorhinolaryngological Cancer | NCT02469922 | Malignant Neopl... Locally Advance... | Positron emissi... radiochemothera... | 18 Years - 75 Years | Center Eugene Marquis | |
| Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer | NCT01434394 | Locally Advance... Oral Cancer Oropharyngeal C... Effects of Chem... | Neo-adjuvant Er... | 18 Years - 75 Years | Shanghai Jiao Tong University School of Medicine | |
| Induction Chemotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT03815903 | Locally Advance... | Induction chemo... Chemoradiothera... | 18 Years - | Barretos Cancer Hospital | |
| Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care | NCT03743649 | Delirium Locally Advance... Metastatic Mali... Recurrent Malig... | Haloperidol Lorazepam Placebo Quality-of-Life... Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center |
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