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Brief Title: Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour
Official Title: A Phase I, Open Label, Multi-Centre Study to Assess the Safety and Tolerability of Cediranib (RECENTIN™, AZD2171) in Combination With Lomustine Chemotherapy for Patients With Primary Recurrent Malignant Brain Tumours for Whom Lomustine Would be a Standard Therapy
Study ID: NCT00503204
Brief Summary: This is a Phase I, open-label, multi-centre study designed to assess the safety and tolerability of Cediranib in combination with lomustine in patients with primary recurrent malignant brain tumour.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Boston, Massachusetts, United States
Research Site, Sutton, , United Kingdom
Name: Jane Robertson
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR
Name: Tracy Batchelor, MD
Affiliation: Massachusetts General Hospital
Role: PRINCIPAL_INVESTIGATOR