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Brief Title: Prevention of Chest Pain in Chemo-treated Cancer Patients
Official Title: Prevention of CArdioToxic-related CHest Pain in Cancer Patients Treated With 5-fluorouracil
Study ID: NCT03486340
Brief Summary: This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will reduce the number of hospitalisations and investigations for acute coronary syndrome during and after 5-FU treatment and that patients with high coronary artery calcium scores are more likely to experience chest pain during the treatment with 5-FU.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Departments of Oncology and Medicine, Vejle Hospital, Vejle, , Denmark
Name: Vibeke B Hansen, MD, PhD
Affiliation: Vejle Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Lars H Jensen, MD, PhD
Affiliation: Department of Oncology, Vejle Hospital, Denmark
Role: STUDY_CHAIR