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Brief Title: Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer
Official Title: A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of KY1044 as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies
Study ID: NCT03829501
Brief Summary: A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their disease, or they have exhausted all such available options in each indication and therefore will be patients for whom a clinical trial is appropriate.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Kymab investigational site 1109, Duarte, California, United States
Kymab investigational site 1102, New Haven, Connecticut, United States
Kymab investigational site 1108, Orlando, Florida, United States
Kymab investigational site 1104, Sarasota, Florida, United States
Kymab investigational site 1103, Nashville, Tennessee, United States
Kymab investigator site 1101, Houston, Texas, United States
Kymab investigational site 3601, Nyíregyháza, Szabolcs-Szatmár-Bereg, Hungary
Kymab investigational site 3602, Budapest, , Hungary
Kymab investigational site 3904, Meldola, Forlì-Cesena, Italy
Kymab investigational site 3906, Candiolo, Torino, Italy
Kymab investigational site 3901, Milano, , Italy
Kymab investigational site 3903, Milano, , Italy
Kymab investigational site 3902, Napoli, , Italy
Kymab investigational site 3910, Roma, , Italy
Kymab investigational site 3908, Turin, , Italy
Kymab investigational site 4801, Siedlce, Mazowieckie, Poland
Kymab investigational site 8806, Changhua City, Changhwa, Taiwan
Kymab investigational site 8801, Taipei, , Taiwan
Kymab investigational site 4405, London, , United Kingdom
Kymab investigational site 4402, Manchester, , United Kingdom
Kymab investigational site 4404, Oxford, , United Kingdom
Kymab investigational site 4401, Sutton, , United Kingdom
Name: Clinical Sciences & Operations
Affiliation: Sanofi
Role: STUDY_DIRECTOR