Neoplasms

Digestive System Diseases

All Conditions

Symptoms and General Pathology

Rare Diseases

Stomach Neoplasms

Esophageal Neoplasms

Hypoxia

Colonic Polyps

Polyps

Pathological Conditions, Anatomical

Signs and Symptoms, Respiratory

Stomach Cancer

Esophageal Cancer

Central Nervous System Depressants

All Drugs and Chemicals

Propofol

In this group, in addition to the standard monitoring including observation, pulse oxygen saturation, non-invasive blood pressure, electrocardiogram in selected patients, the capnographic is also monitored. The capnographic data of the patients are available for additional noninvasive assessment of ventilation.

In this group, standard monitoring including observation, pulse oxygen saturation, non-invasive blood pressure, electrocardiogram in selected patients. Capnographic data are not visible by closing the CO2 sampling line till the endoscopy end.

Standard monitoring and capnographic monitoring.

Capnography monitoring

Standard monitoring but no capnographic monitoring

Standard monitoring

Diansan Su, Dr.

Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol and sufentanil, especially in elderly people. The aim of this randomized study was to determine whether intervention based on additional capnographic monitoring reduces the incidence of hypoxia in gastrointestinal endoscopes procedures for elderly patients.

Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients

Capnographic Monitoring Decrease the Incidence of Hypoxia of the Elderly Patients Undergoing Gastrointestinal Endoscopy Procedure: a Randomized Multicenter Clinical Trial

(SpO2 \< 75% or 75% ≤ SpO2 \< 90% for \>/=60 s)

capnography curve decreased by half or more than the baseline and even disappeared, SpO2 \>90%

Other adverse events recorded by tools proposed by the World Society of Intravenous Anesthesia International Sedation Task Force

Henan Provincial People's Hospital

Qilu Hospital of Shandong University

RenJi Hospital

Vice Chair of the Department of Anesthesiology

In this group, patients use the nasal mask oxygen kit for oxygenation.

In this group, patients use the regular nasal cannula for oxygenation.

Using the nasal mask oxygen kit for oxygenation.

nasal mask oxygen kit

regular nasal cannula

Xiangyang Cheng, B.S.

Jiaqiang zhang, Dr

xiangyang cheng, B.S

jianlin shao, Dr

Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol. The nasal mask oxygen kit has good sealing to ensure an adequate oxygen supply and is convenient and economical.The aim of this randomized study was to determine whether the nasal mask oxygen kit reduces the incidence of hypoxia in gastrointestinal endoscopes procedures.

Nasal Mask Kit in Gastrointestinal Endoscopy

Nasal Mask Oxygen Reduces the Incidence of Hypoxia Undergoing Gastrointestinal Endoscopy Under Propofol Sedation: a Multicenter Randomized Controlled Trial

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients	NCT05030870	Hypoxia Gastric Cancer Gastric Polyp Colon Polyp Colon Cancer Esophageal Canc...	Capnography mon... Standard monito...	65 Years - 79 Years	RenJi Hospital
Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients	NCT05030870	Hypoxia Gastric Cancer Gastric Polyp Colon Polyp Colon Cancer Esophageal Canc...	Capnography mon... Standard monito...	65 Years - 79 Years	RenJi Hospital
Nasal Mask Kit in Gastrointestinal Endoscopy	NCT05405530	Hypoxia Gastric Cancer Gastric Polyp Colon Polyp Colon Cancer Esophageal Canc...	nasal mask oxyg... regular nasal c...	18 Years - 60 Years	RenJi Hospital

Spots Global Cancer Trial Database for capnographic monitoring