Neoplasms

Digestive System Diseases

All Conditions

Nutritional and Metabolic Diseases

Symptoms and General Pathology

Rare Diseases

Stomach Neoplasms

Obesity

Hypoxia

Colonic Polyps

Polyps

Esophageal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Signs and Symptoms, Respiratory

Head and Neck Neoplasms

Esophageal Diseases

Intestinal Polyps

Pathological Conditions, Anatomical

Stomach Cancer

Esophageal Cancer

Oxygen(up to 6L/min) supplied with a regular nasal catheter

Oxygen(up to 60L/min) supplied with high-flow nasal cannula

Oxygen is supplied with a high-flow nasal cannula oxygenation device#the flow is up to 60L/min

High-flow nasal cannula oxygenation

Oxygen is supplied with a regular nasal cannula #the flow is up to 6L/min

Regular nasal cannula

Diansan Su, Dr.

Xiaoqing Zhang, M.S.

Xiangrui Wang, Dr.

Zhang Yuanyuan, B.S.

Hypoxia is the most common adverse event during gastrointestinal endoscopes sedated with propofol and sufentanil, especially in obese people. In the present study, high-flow nasal cannula oxygenation will be utilized in order to reduce the incidence of hypoxia among obesity.

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity: a Randomized Multicenter Clinical Trial

(SpO2 \< 75% for any duration or 75% \< SpO2 \< 90% for \>/=60 s)

Shanghai Tongji Hospital, Tongji University School of Medicine

Shanghai Oriental Hospital, Tongji University School of Medicine

RenJi Hospital

Vice Chair of the Department of Anesthesiology

Central Nervous System Depressants

All Drugs and Chemicals

Propofol

In this group, patients use the nasal mask oxygen kit for oxygenation.

In this group, patients use the regular nasal cannula for oxygenation.

Using the nasal mask oxygen kit for oxygenation.

nasal mask oxygen kit

regular nasal cannula

Xiangyang Cheng, B.S.

Jiaqiang zhang, Dr

xiangyang cheng, B.S

jianlin shao, Dr

Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol. The nasal mask oxygen kit has good sealing to ensure an adequate oxygen supply and is convenient and economical.The aim of this randomized study was to determine whether the nasal mask oxygen kit reduces the incidence of hypoxia in gastrointestinal endoscopes procedures.

Nasal Mask Kit in Gastrointestinal Endoscopy

Nasal Mask Oxygen Reduces the Incidence of Hypoxia Undergoing Gastrointestinal Endoscopy Under Propofol Sedation: a Multicenter Randomized Controlled Trial

(SpO2 \< 75% or 75% ≤ SpO2 \< 90% for \>/=60 s)

Other adverse events recorded by tools proposed by the World Society of Intravenous Anesthesia International Sedation Task Force

Henan Provincial People's Hospital

First Affiliated Hospital of Kunming Medical University

In this group, patients use the COMBO Endoscopy Oropharyngeal Airway for oxygenation.

Using the COMBO Endoscopy Oropharyngeal Airway for oxygenation.

the COMBO Endoscopy Oropharyngeal Airway

Using regular nasal cannula for oxygenation.

Regular Nasal Cannula

Yuhan Zhang, B.S

Cunming Liu, Dr.

Jun Zhang, Dr.

Yonghao Yu, Dr.

Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing gastrointestinal endoscopy with propofol. A recent innovation in this domain is the COMBO Endoscopy Oropharyngeal Airway-a multifaceted device that encompasses capnography monitoring, bite block , oxygenation support, and oropharyngeal airway management. This device has been purposefully designed to cater to the unique requirements of endoscopic procedures. The principal objective of our randomized study is to assess the efficacy and safety of the COMBO Endoscopy Oropharyngeal Airway reduce the incidence of hypoxia on patients undergoing gastrointestinal endoscopy under propofol sedation.

The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure

The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway Reduce the Incidence of Hypoxia in Patients Undergoing Gastrointestinal Endoscopy Sedated With Propofol.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity	NCT04500392	Hypoxia Gastric Cancer Esophagus Cance... Polyp of Colon Colon Cancer	High-flow nasal... Regular nasal c...	18 Years - 70 Years	RenJi Hospital
Nasal Mask Kit in Gastrointestinal Endoscopy	NCT05405530	Hypoxia Gastric Cancer Gastric Polyp Colon Polyp Colon Cancer Esophageal Canc...	nasal mask oxyg... regular nasal c...	18 Years - 60 Years	RenJi Hospital
High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity	NCT04500392	Hypoxia Gastric Cancer Esophagus Cance... Polyp of Colon Colon Cancer	High-flow nasal... Regular nasal c...	18 Years - 70 Years	RenJi Hospital
The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure	NCT06081647	Hypoxia Gastric Polyp Colon Cancer Esophageal Canc...	the COMBO Endos... Regular Nasal C...	18 Years - 60 Years	RenJi Hospital

Spots Global Cancer Trial Database for regular nasal cannula