Neoplasms

All Conditions

Adenoma

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Patients with non-lifting adenomas, adnomas at difficult anaotomic locations , T1-carcinomas or submucosal colorectal tumors

Endoscopic full thickness resection (EFTR)

Arthur R Schmidt, MD

Karel Caca, MD, PhD

Arthur Schmidt, MD

Karel Caca, Prof.

Arthur R Schmidt, Dr.

Observational prospective multicenter study to investigate efficacy and safety of endoscopic full thickness resection in the lower GI tract using a novel over-the-scope full thickness resection device.

The FTRD ("Full Thickness Resection Device", Ovesco Endoscopy, Tübingen, Germany) is an over the scope device consisting of a transparent cap with a preloaded monofilament snare and and a 14 mm modified Over-the-scope Clip. The device is CE marked for full thickness resection in the lower GI tract.

The study was designed to investigate efficacy and safety of this device for full thickness resection of colorectal lesions.

Endoscopic Full Thickness Resection in the Lower GI Tract With the "Full Thickness Resection Device"

Endoscopic Full Thickness Resection in the Lower GI Tract With the "Full Thickness Resection Device"- A Prospective Multicenter Trial

Successful enbloc- and macroscopically complete resection

Histologically confirmed complete resection

Histologically confirmed full thickness resection

Procedure-associated complications such as bleeding or perforation

Ovesco Endoscopy AG

Kliniken Ludwigsburg-Bietigheim gGmbH

Digestive System Diseases

Rare Diseases

Esophageal Neoplasms

Stomach Neoplasms

Colonic Neoplasms

Gastrointestinal Neoplasms

Duodenal Neoplasms

Digestive System Neoplasms

Head and Neck Neoplasms

Gastrointestinal Diseases

Esophageal Diseases

Colorectal Neoplasms

Intestinal Neoplasms

Colonic Diseases

Intestinal Diseases

Stomach Diseases

Duodenal Diseases

Esophageal Cancer

Stomach Cancer

The endoscopic resection is the procedure that allows to remove cancerous or precancerous conditions of digestive tract. Endoscopic resection can be preformed by several techniques:

1. Endoscopic mucosal resection (EMR): it allows to remove mucosal lesions
2. Endoscopic submucosal dissection: it allows to remove mucosal lesions that involved submucosal layer and large lesions
3. Full-thickness resection: it allows to remove infiltrating lesions by the resection of a little piece of the entire gastrointestinal wall

Endoscopic resection

Paolo Cecinato, MD

Matteo Lucarini, MD

The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.

Endoscopic Resection of Gastrointestinal Neoplasms

Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract

the en bloc resection is the ability to remove the neoplasia in a single piece

the complete resection is the ability to remove the neoplasia with clear margins (R0)

recurrence is the recurrence of the neoplasm at the resection site during follow-up

complication rate, early or late, related to the procedure used for endoscopic resection

evaluation of the costs incurred to perform the endoscopic resection

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Endoscopic Full Thickness Resection in the Lower GI Tract With the "Full Thickness Resection Device"	NCT02362126	Colorectal Aden... Submucosal Tumo...	Endoscopic full...	18 Years -	Kliniken Ludwigsburg-Bietigheim gGmbH
Endoscopic Full Thickness Resection in the Lower GI Tract With the "Full Thickness Resection Device"	NCT02362126	Colorectal Aden... Submucosal Tumo...	Endoscopic full...	18 Years -	Kliniken Ludwigsburg-Bietigheim gGmbH
Endoscopic Resection of Gastrointestinal Neoplasms	NCT04780256	Endoscopic Muco... Endoscopic Subm... Gastric Neoplas... Colonic Neoplas... Esophageal Neop... Duodenal Neopla...	Endoscopic rese...	18 Years - 100 Years	Arcispedale Santa Maria Nuova-IRCCS

Spots Global Cancer Trial Database for endoscopic full thickness resection (eftr)