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Spots Global Cancer Trial Database for metronomic chemotherapy

Every month we try and update this database with for metronomic chemotherapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
A Study to Evaluate the Efficacy and Safety of Oral Navelbine in Female Patients With HER2-Negative Metastatic Breast CancerNCT03854617
Human Epidermal...
Oral NVB Metron...
Oral NVB Weekly
18 Years - 85 YearsChineseAMS
Metronomic Chemotherapy in Elderly Non-fit Patients With Aggressive B-Cell LymphomasNCT03161054
Aggressive Non-...
Prednisone
Vinorelbine
Etoposide
Cyclophosphamid...
Rituximab
65 Years - Fondazione Italiana Linfomi - ETS
A Study of the Addition of Metronomic Capecitabine to Standard Adjuvant Therapy in High Risk HER2+ BC paTientsNCT03561740
Breast Cancer
capecitabine
18 Years - 70 YearsSun Yat-sen University
Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With Metronomic VEX in Advanced Triple-negative Breast CancerNCT06229067
Breast Cancer
Triple Negative...
Adebrelimab
Vinorelbine
Cyclophosphamid...
Capecitabine
18 Years - Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDSNCT00744536
Myelodysplastic...
Leukemia, Myelo...
Angiogenesis
Lenalidomide an...
18 Years - Sunnybrook Health Sciences Centre
Maintenance Metronomic Chemotherapy for Metastatic Colorectal CarcinomaNCT01668680
Colorectal Canc...
CAPECITABINE, C...
18 Years - 80 YearsHaEmek Medical Center, Israel
Oral Navelbine and Cisplatin Followed by Metronomic Oral Navelbine in Non-Small Cell Lung CancerNCT02985203
Lung Neoplasm M...
Vinorelbine Ora...
18 Years - Guangdong Association of Clinical Trials
Metronomic Treatment With Daily Oral Vinorelbine as First-line Chemotherapy in Patients With Advanced/Metastatic Hormone Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Breast CancerNCT03007992
Metastatic Brea...
Vinorelbine
18 Years - Johannes Gutenberg University Mainz
ZD6474 (Zactima) and Metronomic Chemotherapy in Advanced Breast CancerNCT00496665
Metastatic Brea...
Vandetanib
Cyclophosphamid...
Methotrexate
18 Years - Dana-Farber Cancer Institute
BP-C1 in Metastatic Breast Cancer PatientsNCT01861509
Metastatic Brea...
Stage IV Breast...
BP-C1
18 Years - 80 YearsMeabco A/S
BP-C1 Monotherapy in Patients With Metastatic Breast Cancer Cancer: Estimation of Optimal Duration of TreatmentNCT03789019
Metastatic Brea...
Stage IV Breast...
BP-C1
18 Years - 80 YearsMeabco A/S
Maintenance Treatment Versus Observation After Induction in Advanced Colorectal CarcinomaNCT00442637
Colorectal Canc...
capecitabine + ...
observation
18 Years - Dutch Colorectal Cancer Group
Capecitabine Maintenance Therapy Following Capecitabine Combined With Docetaxel in Treatment of mBCNCT01917279
Breast Neoplasm...
Neoplasms by Si...
Neoplasm Metast...
Breast Diseases
Skin Diseases
Docetaxel plus ...
Intermittent Ca...
Metronomic Cape...
18 Years - ChineseAMS
BP-C1 in Short-term Treatment of Patients With Metastatic Breast CancerNCT02783794
Metastatic Brea...
Stage IV Breast...
BP-C1
Placebo
18 Years - 80 YearsMeabco A/S
BP-C1 in Short-term Treatment of Metastatic Pancreatic CancerNCT03627390
Metastatic Panc...
Unresectable Pa...
BP-C1
BP-C2
18 Years - 80 YearsMeabco A/S
Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With Metronomic VEX in Advanced Triple-negative Breast CancerNCT06229067
Breast Cancer
Triple Negative...
Adebrelimab
Vinorelbine
Cyclophosphamid...
Capecitabine
18 Years - Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Metronomic Chemotherapy in a Real-world Population of Advanced Breast Cancer PatientsNCT06373744
Breast Cancer
cyclophosphamid...
18 Years - Sun Yat-sen University
Metronomic Cyclophosphamide in Combination With Standard Chemotherapy for Squamous Cell Lung CarcinomaNCT01947062
Lung Cancer
Squamous Cell C...
Locally Advance...
Intravenous Cis...
Intravenous Cis...
18 Years - 75 YearsSwami Rama Cancer Hospital and Research Institute
Bevacizumab With or Without Cyclophosphamide and Methotrexate: A Pilot Study in Women With Operable Breast CancerNCT00121134
Breast Cancer
Bevacizumab
Cyclophosphamid...
Methotrexate
Capecitabine
18 Years - Dana-Farber Cancer Institute
Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906)NCT05384821
Wilms Tumor
Vincristine
Irinotecan
Temozolomide
Etoposide
Cis-Retinoic ac...
18 Months - 17 YearsCentre Oscar Lambret
A Study of the Addition of Metronomic Capecitabine to Standard Adjuvant Therapy in High Risk HER2+ BC paTientsNCT03561740
Breast Cancer
capecitabine
18 Years - 70 YearsSun Yat-sen University
Efficacy of Capecitabine Metronomic Chemotherapy to Triple-negative Breast CancerNCT01112826
Breast Cancer
Capecitabine
18 Years - 70 YearsSun Yat-sen University
Dose-finding Study of BP-C1 in Patients With Stage IV Breast CancerNCT04298333
Metastatic Brea...
Stage IV Breast...
BP-C1
18 Years - 80 YearsMeabco A/S
Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast CancerNCT01067989
Chemotherapy
Breast Cancer, ...
Cyclophosphamid...
18 Years - 80 YearsHaEmek Medical Center, Israel
Metronomic Chemotherapy in a Real-world Population of Advanced Breast Cancer PatientsNCT06373744
Breast Cancer
cyclophosphamid...
18 Years - Sun Yat-sen University
Oral Navelbine and Cisplatin Followed by Metronomic Oral Navelbine in Non-Small Cell Lung CancerNCT02985203
Lung Neoplasm M...
Vinorelbine Ora...
18 Years - Guangdong Association of Clinical Trials
Dose-finding Study of BP-C1 in Patients With Stage IV Breast CancerNCT04298333
Metastatic Brea...
Stage IV Breast...
BP-C1
18 Years - 80 YearsMeabco A/S
Regorafenib in Combination With Metronomic Chemotherapies, and Low-dose Aspirin in Metastatic Colorectal CancerNCT04534218
Colo-rectal Can...
Metastatic Canc...
Regorafenib
Cyclophosphamid...
Capecitabine
Aspirin
18 Years - Centre Hospitalier Universitaire de Besancon
BP-C1 in Short-term Treatment of Metastatic Pancreatic CancerNCT03627390
Metastatic Panc...
Unresectable Pa...
BP-C1
BP-C2
18 Years - 80 YearsMeabco A/S
the Role of Two Different Metronomic Chemotherapy Regimens in Locally Advanced or Metastatic Triple Negative Breast Cancer Patients (TNBC) as Maintenance Therapy After First Line TreatmentNCT03358004
Triple Negative...
Vinorelbine Tar...
Capecitabine 50...
18 Years - Mario Negri Institute for Pharmacological Research
Phase II Trial With Metronomic, Capecitabine Plus Oral Vinorelbine for Metastatic Breast CancerNCT01941771
Breast Cancer
Arm B Vinorelbi...
Arm A Vinorelbi...
18 Years - University of Aarhus
the Role of Two Different Metronomic Chemotherapy Regimens in Locally Advanced or Metastatic Triple Negative Breast Cancer Patients (TNBC) as Maintenance Therapy After First Line TreatmentNCT03358004
Triple Negative...
Vinorelbine Tar...
Capecitabine 50...
18 Years - Mario Negri Institute for Pharmacological Research
Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDSNCT00744536
Myelodysplastic...
Leukemia, Myelo...
Angiogenesis
Lenalidomide an...
18 Years - Sunnybrook Health Sciences Centre
Metronomic Cyclophosphamide in Combination With Standard Chemotherapy for Squamous Cell Lung CarcinomaNCT01947062
Lung Cancer
Squamous Cell C...
Locally Advance...
Intravenous Cis...
Intravenous Cis...
18 Years - 75 YearsSwami Rama Cancer Hospital and Research Institute
Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast CancerNCT01067989
Chemotherapy
Breast Cancer, ...
Cyclophosphamid...
18 Years - 80 YearsHaEmek Medical Center, Israel
Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer PatientsNCT05929885
Metastatic Panc...
Low Dose OXIRI ...
21 Years - 99 YearsNational Cancer Centre, Singapore
Capecitabine Metronomic Chemotherapy Plus Aromatase Inhibitor for Postmenopausal Hormone Receptor Positive Breast CancerNCT01924078
Breast Cancer
Capecitabine
aromatase Inhib...
18 Years - Fudan University
Phase II Trial With Metronomic, Capecitabine Plus Oral Vinorelbine for Metastatic Breast CancerNCT01941771
Breast Cancer
Arm B Vinorelbi...
Arm A Vinorelbi...
18 Years - University of Aarhus
BP-C1 in Short-term Treatment of Thai Patients With Metastatic Breast CancerNCT03603197
Metastatic Brea...
Stage IV Breast...
BP-C1
Placebo
18 Years - 80 YearsMeabco A/S
the Role of Two Different Metronomic Chemotherapy Regimens in Locally Advanced or Metastatic Triple Negative Breast Cancer Patients (TNBC) as Maintenance Therapy After First Line TreatmentNCT03358004
Triple Negative...
Vinorelbine Tar...
Capecitabine 50...
18 Years - Mario Negri Institute for Pharmacological Research
Metronomic Treatment With Daily Oral Vinorelbine as First-line Chemotherapy in Patients With Advanced/Metastatic Hormone Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Breast CancerNCT03007992
Metastatic Brea...
Vinorelbine
18 Years - Johannes Gutenberg University Mainz
Maintenance Treatment Versus Observation After Induction in Advanced Colorectal CarcinomaNCT00442637
Colorectal Canc...
capecitabine + ...
observation
18 Years - Dutch Colorectal Cancer Group
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