Spots Global Cancer Trial Database for microsatellite instability high

Every month we try and update this database with for microsatellite instability high cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Anti-PD-1 +/- RT for MSI-H Solid Tumors	NCT04001101	Microsatellite ... Mismatch Repair... Colorectal Canc...	RT and Anti-PD-... Anti-PD-1	18 Years - 100 Years	University of Colorado, Denver
Microsatellite Instability in Colorectal Cancers	NCT05162248	Colorectal Canc... Colorectal Carc... Microsatellite ... Microsatellite ... Microsatellite ...	Microsatellite ...	18 Years - 100 Years	Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival	NCT04482608	Colorectal Canc... Mismatch Repair... Microsatellite ...		18 Years - 80 Years	Sun Yat-sen University
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors	NCT04234113	Thyroid Renal Cell Carc... Non Small Cell ... Small-cell Lung... Bladder Cancer Melanoma Merkel Cell Car... Skin Squamous C... Microsatellite ... Triple Negative... Mesothelioma Thymic Cancer Cervical Cancer Biliary Tract C... Hepatocellular ... Ovarian Cancer Gastric Cancer Head and Neck S... Anal Cancer	SO-C101 pembrolizumab	18 Years -	Sotio Biotech Inc.
Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types	NCT06034860	Non Small Cell ... Hepatocellular ... Melanoma Renal Cell Carc... Microsatellite ... Mismatch Repair... Mesothelioma Esophageal Squa... Squamous Cell C... Urothelial Carc... Cervical Cancer	MT-8421 Nivolumab	18 Years -	Molecular Templates, Inc.
A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors	NCT05572684	Advanced or Met... Microsatellite ... Microsatellite ... Microsatellite ... Ovarian Cancer Gastric Cancer Colo-rectal Can... Esophageal Canc... Endometrial Can... Head Neck Cance... Cervical Cancer Lung Cancer	NC410 pembrolizumab	18 Years -	NextCure, Inc.
Phase 1a/1b Study of STK-012 Monotherapy and in Combination With Pembrolizumab in Patients With Solid Tumors	NCT05098132	Advanced Solid ... Non Small Cell ... Head and Neck S... Malignant Melan... Renal Cell Carc... Cervical Cancer Microsatellite ... Gastric Cancer GastroEsophagea... Urothelial Carc... Mismatch Repair...	STK-012 Pembrolizumab	18 Years -	Synthekine
PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer	NCT04715633	Colorectal Canc... Microsatellite ...	PD-1 inhibitor ...	18 Years - 75 Years	Sun Yat-sen University
Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors	NCT04116320	Melanoma Breast Cancer Merkel Cell Car... Squamous Cell C... Non Small Cell ... Cervical Cancer Urothelial Carc... Ovarian Cancer Hepatocellular ... Small-cell Lung... Microsatellite ... Gastric Cancer Esophageal Canc...	Echopulse Poly ICLC Standard of Car...	18 Years -	University of Virginia
PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer	NCT04715633	Colorectal Canc... Microsatellite ...	PD-1 inhibitor ...	18 Years - 75 Years	Sun Yat-sen University

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