Neoplasms

All Conditions

Symptoms and General Pathology

Wounds and Injuries

Rare Diseases

Carcinoma

Hyperthermia

Carcinoma, Transitional Cell

Intraoperative Complications

Fever

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Transitional Cell Carcinoma

Participants in the experimental group will be treated with hyperthermic intravesical perfusion before receiving radical cystectomy.

Participants in the control group will receive radical cystectomy alone.

Participants in the experimental group will be treated with hyperthermic intravesical perfusion before receiving radical cystectomy

hyperthermic intravesical perfusion

Huaqi Yin

Huaqi Yin, MD.

To evaluate the effect of hyperthermic intravesical perfusion on the risk of intraoperative implantation of muscle-invasive bladder urothelial carcinoma and its safety.

The participants will be divided into two groups (the experimental group and control group). Participants in the experimental group will be treated with hyperthermic intravesical perfusion before receiving radical cystectomy. Participants in the control group will receive radical cystectomy alone.

After follow-up, the effect of hyperthermic intravesical perfusion on the risk of intraoperative implantation of muscle-invasive bladder urothelial carcinoma and its safety will be evaluated.

The participants will be divided into two groups (the experimental group and control group). Participants in the experimental group will be treated with hyperthermic intravesical perfusion before receiving radical cystectomy. Participants in the control group will receive radical cystectomy alone.

The participants will be randomly (1:1) divided into the experimental and control groups.

Hyperthermic Intravesical Perfusion for Muscle-invasive Bladder Urothelial Carcinoma

The Effect of Hyperthermic Intravesical Perfusion on the Risk of Intraoperative Implantation of Muscle-invasive Bladder Urothelial Carcinoma and Its Safety Analysis

The rate of intraoperative tumor cell dissemination will be evaluated by lavage cytology of operating field

Disease progression was defined as recurrence or metastasis

Henan Cancer Hospital

Digestive System Diseases

Stomach Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Stomach Diseases

Stomach Cancer

Micronutrients

All Drugs and Chemicals

Other Dietary Supplements

Vitamins

Omega 3 Fatty Acid

The patients in this group were treated with omega-3 fish oil fat emulsion at a dose of 100ml/ per person per day for 5 days and added to a three-liter bag (containing water, glucose, amino acids, sodium chloride, vitamins, etc.) except fish oil.

Drug introduction:

Full name: omega-3 fish oil fat emulsion. Common name: Juventus. Specification: 100ml / 10g

Do not use omega-3 fish oil fat emulsion (no omega-3 fish oil fat emulsion is added to the three-liter bag, other substances are the same)

Omega-3 fish oil fat emulsion

Liu Ruiqing, Doctor

Wang Dongsheng, Doctor

The purpose of this study was to investigate the effects of omega-3 fish oil fat emulsion on peripheral blood C-reactive protein, total lymphocyte count, plasma albumin and immune function after radical surgery combined with intraperitoneal hyperthermic perfusion chemotherapy in patients with locally advanced gastric cancer. at the same time, to explore the effects of omega-3 fish oil fat emulsion on complications, length of stay and total cost of hospitalization.

The main question it aims to answer is whether the use of omega-3 fish oil fat emulsion can improve patients' immunity, speed up recovery and reduce costs.

Participants will comprehensively collect patient-related baseline data, including sex, age, BMI, ASA grade, tumor location, histological grade, pathological tumor type, pTNM stage (AJCC cancer stage 8), and perilymphatic vascular / nerve infiltration.

Immune function evaluation related index: peripheral blood lymphocyte count. Plasma albumin concentration, C-reactive protein, postoperative infectious complications, length of stay and cost of hospitalization.

Finally, statistical analysis software was used to analyze the differences between the two groups, evaluate the above indicators and draw mutual conclusions.

The research process is as follows:

1. Select patients in the group according to the inclusion and exclusion criteria.
2. The patient signed the informed consent form
3. His system was used to collect patient data, including human-related baseline data, including sex, age, BMI, ASA grade, tumor location, histological grade, pathological tumor type, pTNM stage (AJCC cancer stage 8th edition), lymphatic vascular / nerve infiltration. Immune function evaluation related index: peripheral blood lymphocyte count. Plasma albumin concentration, C-reactive protein, postoperative infectious complications, length of stay and cost of hospitalization.
4. Using statistical software (SPSS) to judge the statistical difference.
5. It is concluded that the use value of omega-3 fish oil fat emulsion (Ewing) is evaluated.

Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Hyperthermic Intravesical Perfusion for Muscle-invasive Bladder Urothelial Carcinoma	NCT05276167	High-Risk, Non-... Perfusion; Comp... Intraoperative ...	hyperthermic in...	18 Years - 75 Years	Henan Cancer Hospital
Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer	NCT06047158	Fish Oils Perfusion; Comp... Stomach Neoplas... Nutrition Aspec... Chemotherapy Ef... Immunisation Re...	Omega-3 fish oi...	18 Years - 75 Years	The Affiliated Hospital of Qingdao University
Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer	NCT06047158	Fish Oils Perfusion; Comp... Stomach Neoplas... Nutrition Aspec... Chemotherapy Ef... Immunisation Re...	Omega-3 fish oi...	18 Years - 75 Years	The Affiliated Hospital of Qingdao University

Spots Global Cancer Trial Database for perfusion; complications