Spots Global Cancer Trial Database for pharmacokinetic
Every month we try and update this database with for pharmacokinetic cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer Patients | NCT01523431 | Metastatic Colo... | Irinotecan Inje... 5-fluorouracil Leucovorin | 18 Years - | The Affiliated Hospital of the Chinese Academy of Military Medical Sciences | |
| Pharmacokinetic Profile of T-ChOS™ in Subjects With Advanced Solid Tumors (CHITIN) | NCT03320525 | Advanced Solid ... | T-ChOS | 18 Years - 75 Years | Herlev Hospital | |
| CDDO to Treat Solid Tumors and Lymphomas | NCT00322140 | Solid Tumors Lymphoma | CDDO | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| A Study of a Human Anti-Intercellular Adhesion Molecule-1 Monoclonal Antibody, in Patients With Multiple Myeloma | NCT01025206 | Multiple Myelom... | BI-505 | 18 Years - | BioInvent International AB | |
| To Assess the Interaction Between Sunitinib and Ketoconazole to Reduce the Dose and Cost of Sunitinib | NCT01548170 | Cancer | Sunitinib Sunitinib and K... Sunitiinb and K... Sunitinib and K... Sunitinib and K... | 18 Years - 35 Years | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | |
| Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies | NCT02011022 | Methotrexate Ad... | 3g MTX 5g MTX | - 18 Years | The Children's Hospital of Zhejiang University School of Medicine | |
| Study to Investigate the Pharmacolkinetics of Aldoxorubicin (INNO-206;DOXO-EMCH) Administered as a 30 Minute Infusion Every 3 Weeks in Subjects With Advanced Solid Tumors | NCT01706835 | Advanced Solid ... | aldoxorubicin | 18 Years - | ImmunityBio, Inc. | |
| Pharmacokinetic Profile of T-ChOS™ in Subjects With Advanced Solid Tumors (CHITIN) | NCT03320525 | Advanced Solid ... | T-ChOS | 18 Years - 75 Years | Herlev Hospital | |
| A Pharmacokinetic and Randomized Trial of Neoadjuvant Treatment With Anastrozole Plus AZD0530 in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer | NCT01216176 | Breast Cancer | Anastrozole AZD0530 (saraca... Placebo | 18 Years - | University of Miami | |
| A Study of a Human Anti-Intercellular Adhesion Molecule-1 Monoclonal Antibody, in Patients With Multiple Myeloma | NCT01025206 | Multiple Myelom... | BI-505 | 18 Years - | BioInvent International AB | |
| Pharmacokinetics of Apixaban in Patients Undergoing Pancreaticoduodenectomy | NCT04191928 | Pancreas Cancer DVT Pulmonary Embol... | Apixaban | 18 Years - 65 Years | Thomas Jefferson University | |
| Study of the Concentration-effect Relationship of Nivolumab in Patients With Kidney or Lung Cancer | NCT03433534 | Kidney Cancer Lung Cancer | Pharmacokinetic... | 18 Years - | University Hospital, Tours | |
| A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid Tumors | NCT01938443 | Cancer Neoplasms | GSK2256098 Trametinib | 18 Years - | GlaxoSmithKline | |
| Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies | NCT02011022 | Methotrexate Ad... | 3g MTX 5g MTX | - 18 Years | The Children's Hospital of Zhejiang University School of Medicine | |
| A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours | NCT00566410 | Neoplasms | Dichloroacetate | 18 Years - | AHS Cancer Control Alberta | |
| Pharmacokinetic Study of Capecitabine After Total Gastrectomy for Stomach Adenocarcinoma | NCT00871273 | Adenocarcinoma ... | capecitabine | 18 Years - | Cambridge University Hospitals NHS Foundation Trust | |
| Pharmacokinetic Study of Adjuvant Capecitabine After Resection of Pancreatic Adenocarcinoma | NCT00854477 | Pancreatic Aden... | capecitabine | 18 Years - | Cambridge University Hospitals NHS Foundation Trust | |
| To Assess the Interaction Between Sunitinib and Ketoconazole to Reduce the Dose and Cost of Sunitinib | NCT01548170 | Cancer | Sunitinib Sunitinib and K... Sunitiinb and K... Sunitinib and K... Sunitinib and K... | 18 Years - 35 Years | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | |
| A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid Tumors | NCT01938443 | Cancer Neoplasms | GSK2256098 Trametinib | 18 Years - | GlaxoSmithKline | |
| An Open Label Study to Examine the Effects of a High-Fat Meal and Particle Size on the Pharmacokinetics of Orally Administered GSK2118436 in Subjects With BRAF Mutation Positive Tumor | NCT01231568 | Cancer | Regimen A Regimen B Regimen C Regimen D | 18 Years - | GlaxoSmithKline | |
| Study to Investigate the Pharmacolkinetics of Aldoxorubicin (INNO-206;DOXO-EMCH) Administered as a 30 Minute Infusion Every 3 Weeks in Subjects With Advanced Solid Tumors | NCT01706835 | Advanced Solid ... | aldoxorubicin | 18 Years - | ImmunityBio, Inc. | |
| A Pharmacokinetic Study of Zolbetuximab (IMAB362) in Chinese Subjects With Locally Advanced Unresectable or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma | NCT04086758 | Gastric or Gast... | zolbetuximab | 18 Years - | Astellas Pharma Inc | |
| Ketoconazole Administration: How it is Affected by the Body and Broken Down and How it Acts on the Body When Used With Velcade | NCT00129207 | Tumors | bortezomib | 18 Years - | Millennium Pharmaceuticals, Inc. | |
| Pharmacokinetic Study of Docetaxel-PNP and Taxotere to Treat Patient With Advanced Solid Cancer | NCT02274610 | Solid Tumor | Docetaxel-PNP Taxotere | 18 Years - | Samyang Biopharmaceuticals Corporation | |
| CDDO to Treat Solid Tumors and Lymphomas | NCT00322140 | Solid Tumors Lymphoma | CDDO | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Clinical Trial for Assessment of Anti-SARS-CoV-2 Serum for Early Treatment of COVID-19 Cases | NCT04834089 | Immunosuppressi... Cancer COVID-19 Other Complicat... Chemotherapy Renal Disease Diabetes Mellit... Cardiovascular ... Chronic Obstruc... | AntiSARS-CoV-2 ... Placebo | 18 Years - | Butantan Institute | |
| Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics | NCT05534620 | Acute Myeloid L... Myelodysplastic... Allogeneic Hema... | Treosulfan Fludarabine | 18 Years - 80 Years | medac GmbH | |
| Pharmacokinetic Study of Docetaxel-PNP and Taxotere to Treat Patient With Advanced Solid Cancer | NCT02274610 | Solid Tumor | Docetaxel-PNP Taxotere | 18 Years - | Samyang Biopharmaceuticals Corporation | |
| Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome | NCT01366391 | Polycystic Ovar... | Metformin | 18 Years - 40 Years | Biocinese | |
| POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus | NCT02093598 | Carcinoma, Endo... mTOR Protein | Temsirolimus | 18 Years - | MedSIR | |
| Pharmacokinetic and Radiation Dosimetry Study Evaluating 99m TC-EC-DG SPECT/CT in Patients With Non-small Cell Lung Cancer (NSCLC) | NCT00864110 | Non Small Cell ... | Radiolabeled (9... Technetium 99m ... 18 F fluorodeox... | 18 Years - | Cell>Point LLC | |
| Association Between Side Effects Occurrence and Concentrations of Ibrutinib and Idelalisib | NCT02824159 | Hematological M... | Blood samples f... Imagery Quality of life... Detection of ad... Saliva samples Blood sample Biological stat... Clinical examin... | 18 Years - | University Hospital, Toulouse | |
| Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma | NCT00109005 | Melanoma | Revlimid | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Pharmacokinetic Study of Doxorubicin in Children With Cancer | NCT01095926 | Wilms Tumor Neuroblastoma Soft Tissue Sar... Acute Lymphobla... | doxorubicin | - 17 Years | University Hospital Muenster | |
| A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT01484847 | Head and Neck S... | PF-00299804 | 18 Years - | University Health Network, Toronto | |
| Clinical Trial for Assessment of Anti-SARS-CoV-2 Serum for Early Treatment of COVID-19 Cases | NCT04834089 | Immunosuppressi... Cancer COVID-19 Other Complicat... Chemotherapy Renal Disease Diabetes Mellit... Cardiovascular ... Chronic Obstruc... | AntiSARS-CoV-2 ... Placebo | 18 Years - | Butantan Institute | |
| Hepatic Impairment Study for Lorlatinib in Cancer Patients | NCT03726333 | Advanced Cancer... | lorlatinib lorlatinib lorlatinib lorlatinib lorlatinib | 18 Years - | Pfizer | |
| Hepatic Impairment Study for Lorlatinib in Cancer Patients | NCT03726333 | Advanced Cancer... | lorlatinib lorlatinib lorlatinib lorlatinib lorlatinib | 18 Years - | Pfizer | |
| Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum | NCT00094978 | Carcinoma, Smal... Carcinoma, Non-... Esophageal Neop... Mesothelioma | Depsipeptide Flavopiridol (a... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies | NCT02011022 | Methotrexate Ad... | 3g MTX 5g MTX | - 18 Years | The Children's Hospital of Zhejiang University School of Medicine | |
| Repeat-Dose Pharmacokinetics and Pharmacodynamics of Bortezomib in Patients With Relapsed Multiple Myeloma | NCT00080405 | Multiple Myelom... | Bortezomib | 18 Years - | Millennium Pharmaceuticals, Inc. | |
| A Pharmacokinetic Study of Zolbetuximab (IMAB362) in Chinese Subjects With Locally Advanced Unresectable or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma | NCT04086758 | Gastric or Gast... | zolbetuximab | 18 Years - | Astellas Pharma Inc |
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